Results 51 to 60 of about 4,260 (165)

Orthopoxvirus real-time PCR v1

, 2018
A real-time PCR targeting the DNA-dependent RNA polymerase of Orthopoxviruses.
Judy A Northill, Ian M Mackay, David Warrilow   +2 more
core   +1 more source

Assessment of Animal Sensitivity to Particularly Dangerous Orthopoxviruses, Using Primary Cultures of Lung Cells [PDF]

, 2016
Objective of the study is to investigate the sensitivity of different animals to highly pathogenic Orthopoxviruses applying techniques, based on utilization of primary cultures of lung cells, and to assess the possibility of further deployment of this ...
K. A. Titova, A. E. Nesterov, D. O. Galakhova, Ar. A. Sergeev, A. S. Kabanov, L. E. Bulychev, O. V. Nosareva, Al. A. Sergeev, A. N. Sergeev, A. P. Agafonov, L. N. Shishkina, A. S. Zamedyanskaya, D.O. Galakhova, A.E. Nesterov, A.P. Agafonov, O.V. Nosareva, L.N. Shishkina, Al.A. Sergeev, A.S. Zamedyanskaya, A.N. Sergeev, A.S. Kabanov, K.A. Titova, null null, L.E. Bulychev, Ar.A. Sergeev   +24 more
core   +1 more source

Replication Data for: Exaptation of inactivated host enzymes for structural roles in orthopoxviruses and novel protein folds revealed by protein structure modeling

, 2023
Viruses with large double-stranded DNA genomes appear to have captured the majority of their genes from the hosts at different stages of evolution. The origin of many virus genes is readily detected through highly significant sequence similarity with ...
Koonin, Eugene V., Mutz, Pascal (*), Senkevich, Tatiana G., Resch, Wolfgang (*), Faure, Guilhem, Moss, Bernard   +5 more
core   +1 more source

Epidemiology of Horsepox. The New Aspects

Вестник войск РХБ защиты
In the last 10 years, scientists' interest in the horsepox pathogen has increased sharply due to the obtaining of its chimeric copy and the discussion of whether it was used to create early smallpox vaccines and the dangers of technologies that allow the
L. F. Stovba, A. A. Petrov, S. A. Melnikov, O. V. Chukhralia, N. K. Cherniкova, S. V. Borisevich   +5 more
doaj   +1 more source

Readiness Level of Spanish Labs to Detect Mpox Clade Ib: A Nationwide EQA

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT To assess the preparedness and diagnostic capacity of Spanish clinical microbiology laboratories to detect the emerging monkeypox virus (MPXV) Clade Ib through a nationwide external quality assessment. A blinded 16‐sample panel (serum and DNA eluates) containing MPXV Clade Ib, Clade II, vaccinia, and negatives was distributed.
Adolfo De Salazar, Anabel Negredo, Juan Carlos Galán, Teresa Del Peso, Marta Illescas, Laura Martínez‐García, Concepción Gimeno, Federico García, María Paz Sánchez‐Seco, the QC Mpox Spain Collaborators, Sonia Algarate, Andrés Antón, Ana Milagro, Fernando Buñuel, Laura Calatayud, Pilar Catalán, Gregorio Marañón, Marta Domínguez‐Gil González, Manel Flores, Pablo Fraile, Ana Fuentes López, María del Carmen Garma, Mª Dolores Gómez‐Ruíz, Mónica Gozalo, Manuel Grau, Almudena Gutiérrez‐Arroyo, Silvia Hernáez, Águeda Hernández‐Rodríguez, Noelia Hernando, Flor Isabel Hidalgo, José Luis Juan, Eduardo Lagarejos, Miguel Julián Martínez‐Yoldi, Santiago Melón, Pablo Mendoza, Laura Merino, Milagrosa Montes, Jordi Niubó, María Dolores Ocete, Alejandra Pérez‐García, Jorge Alfredo Pérez‐García, Mercedes Pérez‐Ruiz, Sonia Pérez‐Castro, Jordi Reina, Romina Soledad Romero, Genoveva Santillana, Encarna Simarro, Mikel Urruticoechea, Laura Herrero, Francisca Molero   +49 more
wiley   +1 more source

Rapid and sensitive point-of-care detection of Orthopoxviruses by ABICAP immunofiltration [PDF]

, 2016
Background: The rapid and reliable detection of infectious agents is one of the most challenging tasks in scenarios lacking well-equipped laboratory infrastructure, like diagnostics in rural areas of developing countries.
Scott K. Smith, Marko Pietraszczyk, Olson, Victoria A., Nitsche, Andreas, Victoria A. Olson, Smith, Scott K., Andreas Nitsche, Stern, Daniel, Daniel Stern, Pietraszczyk, Marko, Peter Miethe, Lilija Miller, Miller, Lilija, Dorner, Brigitte, Brigitte G. Dorner, Miethe, Peter   +15 more
core   +1 more source

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Animal Models and Experimental Medicine, Volume 9, Issue 4, Page 829-837, April 2026.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiangning Liu   +9 more
wiley   +1 more source

Rabbitpox

Вестник войск РХБ защиты
There is a danger that a natural smallpox virus may be reintroduced from the unknown spring or that a similar virus with the same pathogenic properties may appear or that somebody may create a synthetic copy of such a virus.
Lyudmila F. Stovba, Aleksandr A. Petrov, Dеnis P. Belozerov, Oleg V. Chukhralia, Sergey A. Melnikov, Sergey V. Borisevich   +5 more
doaj   +1 more source

Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+ T cells post peptide loading.

PLoS Pathogens, 2020
Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the cause of mousepox.
Katherine S Forsyth, Nathan H Roy, Elise Peauroi, Brian C DeHaven, Erik D Wold, Adam R Hersperger, Janis K Burkhardt, Laurence C Eisenlohr   +7 more
doaj   +1 more source

Orthopoxvirus real-time PCR v2

, 2018
A real-time PCR targeting the DNA-dependent RNA polymerase of Orthopoxviruses.
Judy A Northill, Ian M Mackay, David Warrilow   +2 more
core   +1 more source