Results 71 to 80 of about 4,260 (165)

Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil

Viruses
Domestic animals can share viral pathogens with humans, acting mainly as a bridge host. The Orthopoxvirus genus hosts important zoonotic species that have emerged in urban areas worldwide.
Débora de Meneses, Ana G. Stoffella-Dutra, Vicenzo S. Blaso, Iara M. de Almeida, Karolina L. Dias, Iago José da S. Domingos, Gabriela P. Ribeiro, Wendel Coura-Vital, Alexandre B. Reis, Thallyta M. Vieira, Giliane de S. Trindade   +10 more
doaj   +1 more source

We should be prepared to smallpox re-emergence

Вопросы вирусологии, 2019
The review contains a brief analysis of the results of investigations conducted during 40 years after smallpox eradication and directed to study genomic organization and evolution of variola virus (VARV) and development of modern diagnostics, vaccines ...
S. N. Shchelkunov, G. A. Shchelkunova
doaj   +1 more source

An increasing danger of zoonotic orthopoxvirus infections. [PDF]

, 2013
On May 8, 1980, the World Health Assembly at its 33(rd) session solemnly declared that the world and all its peoples had won freedom from smallpox and recommended ceasing the vaccination of the population against smallpox. Currently, a larger part of the
Shchelkunov Sergei N., Sergei N Shchelkunov   +1 more
core   +1 more source

The Effects of the Combined Co-Expression of GroEL/ES and Trigger Factor Chaperones on Orthopoxvirus Phospholipase F13 Production in E. coli

BioTech
Heterologous protein expression often faces significant challenges, particularly when the target protein has posttranslational modifications, is toxic, or is prone to misfolding. These issues can result in low expression levels, aggregation, or even cell
Iuliia A. Merkuleva, Vladimir N. Nikitin, Tatyana D. Belaya, Egor. A. Mustaev, Dmitriy N. Shcherbakov   +4 more
doaj   +1 more source

Assessing Monkeypox Virus Prevalence in Small Mammals at the Human–Animal Interface in the Democratic Republic of the Congo

Viruses, 2017
During 2012, 2013 and 2015, we collected small mammals within 25 km of the town of Boende in Tshuapa Province, the Democratic Republic of the Congo. The prevalence of monkeypox virus (MPXV) in this area is unknown; however, cases of human infection were ...
Jeffrey B. Doty, Jean M. Malekani, Lem’s N. Kalemba, William T. Stanley, Benjamin P. Monroe, Yoshinori U. Nakazawa, Matthew R. Mauldin, Trésor L. Bakambana, Tobit Liyandja Dja Liyandja, Zachary H. Braden, Ryan M. Wallace, Divin V. Malekani, Andrea M. McCollum, Nadia Gallardo-Romero, Ashley Kondas, A. Townsend Peterson, Jorge E. Osorio, Tonie E. Rocke, Kevin L. Karem, Ginny L. Emerson, Darin S. Carroll   +20 more
doaj   +1 more source

Orthopoxvirus real-time PCR v3

, 2018
A real-time PCR targeting the DNA-dependent RNA polymerase of Orthopoxviruses. This protocol was designed and developed at this laboratory.
Judy A Northill, Ian M Mackay, David Warrilow   +2 more
core   +1 more source

Natural killer cells expanded in vivo or ex vivo with IL-15 overcomes the inherent susceptibility of CAST mice to lethal infection with orthopoxviruses

, 2020
The wild-derived inbred CAST/EiJ mouse, one of eight founder strains in the Collaborative Cross panel, is an exceptional model for studying monkeypox virus (MPXV), an emerging human pathogen, and other orthopoxviruses including vaccinia virus (VACV ...
Bernard Moss (132301), Patricia L Earl, Jeffrey L Americo, Patricia L. Earl (8748759), Bernard Moss, Jeffrey L. Americo (8748762), Jeffrey L. Americo, Patricia L. Earl   +7 more
core   +1 more source

Comparative analysis of the taxonomic classification criteria for a number of groups of pathogenic DNA and RNA viruses based on genomic data

Вопросы вирусологии
The basis for criteria of the taxonomic classification of DNA and RNA viruses based on data of the genomic sequencing are viewed in this review. The genomic sequences of viruses, which have genome represented by double-stranded DNA (orthopoxviruses as ...
Tatiana E. Sizikova, Vitaliy N. Lebedev, Sergey V. Borisevich   +2 more
doaj   +1 more source

Complex Approach to Species-Specific Detection of Cowpox Virus

Проблемы особо опасных инфекций, 2016
Objective of the study is to develop and validate the method for species-specific detection of cowpox virus (CPV). Materials and methods. Utilized were oligonucleotide primers and fluorescence-labeled probes for genus-specific detection of ...
R. A. Maksyutov
doaj   +1 more source

Identifying potential monkeypox virus inhibitors: an in silico study targeting the A42R protein

Frontiers in Cellular and Infection Microbiology
Monkeypox (now Mpox), a zoonotic disease caused by the monkeypox virus (MPXV) is an emerging threat to global health. In the time span of only six months, from May to October 2022, the number of MPXV cases breached 80,000 and many of the outbreaks ...
Carolyn N. Ashley, Emmanuel Broni, Chanyah M. Wood, Chanyah M. Wood, Tunmise Okuneye, Tunmise Okuneye, Mary-Pearl T. Ojukwu, Mary-Pearl T. Ojukwu, Mary-Pearl T. Ojukwu, Qunfeng Dong, Qunfeng Dong, Carla Gallagher, Whelton A. Miller, Whelton A. Miller   +13 more
doaj   +1 more source