Synergid cell calcium oscillations refine understanding of FERONIA/LORELEI signaling during interspecific hybridization [PDF]
Plant Reproduction, 2023 Abstract Key message Pollen tubes from closely related species and mutants lacking pollen tube MYB transcription factors are able to initiate FER/LRE-dependent synergid cell calcium oscillations. Abstract Reproductive isolation leads to the evolution of new species; however,
Nathaniel Ponvert, Mark A. Johnson
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Purinergic signalling is required for calcium oscillations in migratory chondrogenic progenitor cells [PDF]
Pflügers Archiv - European Journal of Physiology, 2014 Osteoarthritis (OA) is the most common form of chronic musculoskeletal disorders. A migratory stem cell population termed chondrogenic progenitor cells (CPC) with in vitro chondrogenic potential was previously isolated from OA cartilage. Since intracellular Ca(2+) signalling is an important regulator of chondrogenesis, we aimed to provide a detailed ...
Csaba Matta +8 more
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PLOS ONE, 2016 Circadian clocks impact vital cardiac parameters such as blood pressure and heart rate, and adverse cardiac events such as myocardial infarction and sudden cardiac death. In mammals, the central circadian pacemaker, located in the suprachiasmatic nucleus of the hypothalamus, synchronizes cellular circadian clocks in the heart and many other tissues ...
Stephen Beesley +2 more
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ATP-Independent Luminal Oscillations and Release of Ca2+ and H+ from Mast Cell Secretory Granules: Implications for Signal Transduction [PDF]
Biophysical Journal, 2003 InsP(3) is an important link in the intracellular information network. Previous observations show that activation of InsP(3)-receptor channels on the granular membrane can turn secretory granules into Ca(2+) oscillators that deliver periodic trains of Ca(2+) release to the cytosol (T. Nguyen, W. C. Chin, and P.
Iván Quesada +2 more
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Cell Signaling Microdomain with Na,K-ATPase and Inositol 1,4,5-Trisphosphate Receptor Generates Calcium Oscillations [PDF]
Journal of Biological Chemistry, 2003 Recent studies indicate novel roles for the ubiquitous ion pump, Na,K-ATPase, in addition to its function as a key regulator of intracellular sodium and potassium concentration. We have previously demonstrated that ouabain, the endogenous ligand of Na,K-ATPase, can trigger intracellular Ca2+ oscillations, a versatile intracellular signal controlling a ...
Ayako Miyakawa-Naito +7 more
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Regulation of molecular clock oscillations and phagocytic activity via muscarinic Ca2+ signaling in human retinal pigment epithelial cells [PDF]
Scientific Reports, 2017 AbstractVertebrate eyes are known to contain circadian clocks, however, the intracellular mechanisms regulating the retinal clockwork remain largely unknown. To address this, we generated a cell line (hRPE-YC) from human retinal pigmental epithelium, which stably co-expressed reporters for molecular clock oscillations (Bmal1-luciferase) and ...
Rina Ikarashi +9 more
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Origins of Ultrasensitivity and Complex Signaling Dynamics of Cellular Hydrogen Peroxide and Peroxiredoxin [PDF]
AntioxidantsHydrogen peroxide (H2O2) plays a crucial role in cell signaling in response to physiological and environmental perturbations. H2O2 can oxidize typical 2-Cys peroxiredoxin (PRX) first into a sulfenic acid, which resolves into a disulfide that can be ...
Shengnan Liu, Jingbo Pi, Qiang Zhang
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BiologyThe oscillation synchronization analysis in biological systems will expand our knowledge about the response of living systems to changes in environmental conditions. This knowledge can be used in medicine (diagnosis, therapy, monitoring) and agriculture (increasing productivity, resistance to adverse effects).
Maxim E. Astashev +6 more
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Ca 2+ oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca 2+ signal integrators [PDF]
Proceedings of the National Academy of Sciences, 2008 The role of Ca 2+ signaling in triggering hypertrophy was investigated in neonatal rat cardiomyocytes in vitro . We show that an increase in cell size and sarcomere reorganization were elicited by receptor agonists such as Angiotensin II, aldosterone, and norepinephrine and by a small rise in
Matilde Colella +5 more
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Repetitive mitochondrial Ca 2+ signals synchronize with cytosolic Ca 2+ oscillations in the pancreatic beta-cell line, MIN6 [PDF]
Diabetologia, 1998 We examined the relationship between cytosolic Ca2+ concentration ([Ca2+]c) and mitochondrial matrix Ca2+ concentration ([Ca2+]m) in the pancreatic beta-cell line, MIN6. [Ca2+]c was monitored in a single or a group (30 cells) of fura-2-loaded MIN6 cells, and [Ca2+]m was measured in a group (1 x 10[6] cells) of MIN6 cells stably transfected with ...
Mitsuhiro Nakazaki +9 more
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