Results 11 to 20 of about 1,299,623 (327)

Computer identification of Notch3 in the neurogenic progenitor cells of mammalian early optic vesicles [PDF]

open access: yesBMC Research Notes
Objective The developing mammalian retina initially contains undifferentiated cells, providing a model for investigating the mechanisms of differentiation.
Yoshitoku Watabe   +3 more
doaj   +2 more sources

Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:To control and manipulate cellular signaling, we need to understand cellular strategies for information transfer, integration, and decision-making.
Fernando Siso-Nadal   +4 more
doaj   +2 more sources

Ca 2+ oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca 2+ signal integrators

open access: greenProceedings of the National Academy of Sciences of the United States of America, 2008
Matilde Colella   +5 more
openalex   +2 more sources

Origins of Ultrasensitivity and Complex Signaling Dynamics of Cellular Hydrogen Peroxide and Peroxiredoxin [PDF]

open access: yesAntioxidants
Hydrogen peroxide (H2O2) plays a crucial role in cell signaling in response to physiological and environmental perturbations. H2O2 can oxidize typical 2-Cys peroxiredoxin (PRX) first into a sulfenic acid, which resolves into a disulfide that can be ...
Shengnan Liu, Jingbo Pi, Qiang Zhang
doaj   +2 more sources

The Roles of Fission Yeast Ase1 in Mitotic Cell Division, Meiotic Nuclear Oscillation, and Cytokinesis Checkpoint Signaling

open access: greenMolecular Biology of the Cell, 2005
Akira Yamashita   +4 more
openalex   +2 more sources

Cholesterol-induced robust Ca oscillation in astrocytes required for survival and lipid droplet formation in high-cholesterol condition

open access: yesiScience, 2022
Summary: Cholesterol, one of the major cell membrane components, stabilizes membrane fluidity and regulates signal transduction. Beside its canonical roles, cholesterol has been reported to directly activate signaling pathways such as hedgehog (Hh).
Chihiro Adachi   +2 more
doaj   +1 more source

Substrate stiffness-dependent regulatory volume decrease and calcium signaling in chondrocytes

open access: yesActa Biochimica et Biophysica Sinica, 2021
The pericellular matrix stiffness is strongly associated with its biochemical and structural changes during the aging and osteoarthritis progress of articular cartilage.
Zhang Min   +4 more
doaj   +1 more source

Oscillations Governed by the Incoherent Dynamics in Necroptotic Signaling

open access: yesFrontiers in Physics, 2021
Emerging evidences have suggested that oscillation is important for the induction of cell death. However, whether and how oscillation behavior is involved and required for necroptosis remain elusive.
Fei Xu   +12 more
doaj   +1 more source

Dynamic intracellular mechanical cues facilitate collective signaling responses

open access: yesiScience, 2021
Summary: Collective behavior emerges in diverse life machineries, e.g., the immune responses to dynamic stimulations. The essential questions that arise here are that whether and how cells in vivo collectively respond to stimulation frequencies higher ...
Bingchen Che   +7 more
doaj   +1 more source

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