Results 61 to 70 of about 49,244 (292)
Journal of Circadian Rhythms, 2023 The circadian clock regulates the “push-pull” of the molecular signaling mechanisms that arrange the rhythmic organization of the physiology to maintain cellular homeostasis. In mammals, molecular clock genes tightly arrange cellular rhythmicity.
Yalcin Erzurumlu +2 more
doaj +1 more source
Miro1-dependent mitochondrial dynamics in parvalbumin interneurons
eLife, 2021 The spatiotemporal distribution of mitochondria is crucial for precise ATP provision and calcium buffering required to support neuronal signaling.
Georgina Kontou +9 more
doaj +1 more source
Lattice gas cellular automata model for rippling and aggregation in myxobacteria
, 2004 A lattice-gas cellular automaton (LGCA) model is used to simulate rippling and aggregation in myxobacteria. An efficient way of representing cells of different cell size, shape and orientation is presented that may be easily extended to model later ...
Buchard +32 more
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Frontiers in Cell and Developmental Biology, 2019 The mammalian target of rapamycin (mTOR) is an evolutionarily conserved kinase which assembles a signaling network that integrates diverse biochemical and mechanical cues to coordinate cell growth and proliferation.
Shan-Shan Lin, Ya-Wen Liu, Ya-Wen Liu
doaj +1 more source
Human iNKT Cells Promote Protective Inflammation by Inducing Oscillating Purinergic Signaling in Monocyte-Derived DCs [PDF]
Cell Reports, 2016 Invariant natural killer T (iNKT) cells are innate T lymphocytes that promote host defense against a variety of microbial pathogens. Whether microbial ligands are required for their protective effects remains unclear. Here, we show that iNKT cells stimulate human-monocyte-derived dendritic cells (DCs) to produce inflammatory mediators in a manner that ...
Nathan M. Sherer +11 more
openaire +4 more sources
G protein-coupled receptor signalling in astrocytes in health and disease: A focus on metabotropic glutamate receptors [PDF]
, 2012 Work published over the past 10–15 years has caused the neuroscience community to engage in a process of constant re-evaluation of the roles of glial cells in the mammalian central nervous system.
Bradley, Sophie J., Challiss, R.A. John
core +1 more source
The role of calcium oscillations in the phenotype selection in endothelial cells
Scientific Reports, 2021 Angiogenesis is an important process in the formation and maintenance of tissues which is driven by a complex system of intracellular and intercellular signaling mechanisms.
Birses Debir +3 more
doaj +1 more source
Noise-induced Input Dependence in a Convective Unstable Dynamical System
, 1998 Unidirectionally coupled dynamical system is studied by focusing on the input (or boundary) dependence. Due to convective instability, noise at an up-flow is spatially amplified to form an oscillation. The response, given by the down-flow dynamics, shows
Fujimoto, Koichi, Kaneko, Kunihiko
core +1 more source
Genetic disruption of the core circadian clock impairs hippocampus-dependent memory [PDF]
, 2014 Perturbing the circadian system by electrolytically lesioning the suprachiasmatic nucleus (SCN) or varying the environmental light:dark schedule impairs memory, suggesting that memory depends on the circadian system.
Chen, Xuanmao +4 more
core +2 more sources
Dynamic expression of Notch signaling genes in neural stem/progenitor cells
Frontiers in Neuroscience, 2011 In neural stem/progenitor cells, expression of the Notch effector Hes1, a transcriptional repressor, oscillates with a period of 2-3 hours by negative feedback, and Hes1 oscillations induce the oscillatory expression of the proneural gene Neurogenin2 ...
Hiromi eShimojo +2 more
doaj +1 more source