Results 21 to 30 of about 34,354 (193)

A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir

Virology Journal, 2010
Background Oseltamivir is the preferred antiviral drug for influenza, but oseltamivir-resistant A(H1N1) viruses have circulated worldwide since the 2007-2008 influenza season.
Itagaki Tsutomu, Takashita Emi, Sugawara Kanetsu, Sanjoh Kanako, Abiko Chieko, Suto Asuka, Aoki Yoko, Mizuta Katsumi, Matsuzaki Yoko, Katsushima Yuriko, Ujike Makoto, Obuchi Masatsugu, Odagiri Takato, Tashiro Masato   +13 more
doaj   +1 more source

A Cross-Sectional Study of Psychiatric Manifestations Following Oseltamivir Administration for Suspected Patients with H1N1 Swine Influenza Infection [PDF]

Journal of Cardio-Thoracic Medicine, 2022
Introduction: Oseltamivir is an antiviral drug used to treat H1N1 influenza. FDA added a warning to the label of oseltamivir drawing attention to the risk of developing neuropsychiatric adverse events.
Basavaraju Jayadeva, Shankar Kumar, Sushmitha Kota, Aashik Shekar   +3 more
doaj   +1 more source

Anti-influenza neuraminidase inhibitor oseltamivir phosphate induces canine mammary cancer cell aggressiveness. [PDF]

PLoS ONE, 2015
Oseltamivir phosphate is a widely used anti-influenza sialidase inhibitor. Sialylation, governed by sialyltransferases and sialidases, is strongly implicated in the oncogenesis and progression of breast cancer.
Joana T de Oliveira, Ana L Santos, Catarina Gomes, Rita Barros, Cláudia Ribeiro, Nuno Mendes, Augusto J de Matos, M Helena Vasconcelos, Maria José Oliveira, Celso A Reis, Fátima Gärtner   +10 more
doaj   +1 more source

Comparative effectiveness of oseltamivir versus peramivir for hospitalized children (aged 0-5 years) with influenza infection

International Journal of Infectious Diseases, 2023
Objectives: The effectiveness of oseltamivir versus peramivir in children infected with influenza remains unclear. This study aimed to evaluate their effectiveness in young children (aged 0-5 years) infected with severe influenza A virus (IAV) or ...
Ming Xu, Ting Cai, Tingting Yue, Pan Zhang, Jie Huang, Qi Liu, Yue Wang, Ruping Luo, Zhengqiu Li, Linli Luo, Chunyi Ji, Xinrui Tan, Yanling Zheng, Richard Whitley, Erik De Clercq, Qiang Yin, Guangdi Li   +16 more
doaj   +1 more source

Tracking oseltamivir-resistance in New Zealand influenza viruses during a medicine reclassification in 2007, a resistant-virus importation in 2008 and the 2009 pandemic

Western Pacific Surveillance and Response, 2012
Introduction: Oseltamivir (Tamiflu®) is an important pharmaceutical intervention against the influenza virus. The importance of surveillance for resistance to oseltamivir has been highlighted by two global events: the emergence of an oseltamivir ...
Q Sue Huang, Jing Wang, Wendy Gunn, Molly Ziki, Mackenzie Nicol, Judy Bocacao, Jacqui C Ralston, Danielle J de Joux, Matthew Peacey, Richard J Hall   +9 more
doaj   +1 more source

Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir. [PDF]

PLoS ONE, 2015
Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses.
Eun-Hye Hong, Jae-Hyoung Song, Aeri Shim, Bo-Ra Lee, Bo-Eun Kwon, Hyuk-Hwan Song, Yeon-Jeong Kim, Sun-Young Chang, Hyeon Gun Jeong, Jong Geal Kim, Sang-Uk Seo, HyunPyo Kim, YongSoo Kwon, Hyun-Jeong Ko   +13 more
doaj   +1 more source

Systematic review and meta-analysis of the efficacy and safety of oseltamivir (Tamiflu) in the treatment of Coronavirus Disease 2019 (COVID-19).

PLoS ONE, 2022
Efforts are ongoing by researchers globally to develop new drugs or repurpose existing ones for treating COVID-19. Thus, this led to the use of oseltamivir, an antiviral drug used for treating influenza A and B viruses, as a trial drug for COVID-19 ...
Basiru Aliyu, Yakubu Egigogo Raji, Hui-Yee Chee, Mui-Yun Wong, Zamberi Bin Sekawi   +4 more
doaj   +2 more sources

Oseltamivir Enhances Hippocampal Network Synchronization

Journal of Pharmacological Sciences, 2008
Oseltamivir, a widely used anti-influenza drug, inhibits virus neuraminidase. A mammalian homologue of this enzyme is expressed in the brain, yet the effect of oseltamivir on central neurons is largely unknown.
Atsushi Usami, Takuya Sasaki, Nobuhiro Satoh, Takahiro Akiba, Satoshi Yokoshima, Tohru Fukuyama, Kenzo Yamatsugu, Motomu Kanai, Masakatsu Shibasaki, Norio Matsuki, Yuji Ikegaya   +10 more
doaj   +1 more source

Characteristics of Patients with Oseltamivir-Resistant Pandemic (H1N1) 2009, United States

Emerging Infectious Diseases, 2011
During April 2009–June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant.
Samuel B. Graitcer, Larisa Gubareva, Laurie Kamimoto, Saumil Doshi, Meredith Vandermeer, Janice Louie, Christine Waters, Zack Moore, Katrina Sleeman, Margaret Okomo-Adhiambo, Steven A. Marshall, Kirsten St. George, Chao-Yang Pan, Jennifer M. LaPlante, Alexander Klimov, Alicia M. Fry   +15 more
doaj   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources