Results 21 to 30 of about 24,935 (185)

Meeting Report: Risk Assessment of Tamiflu® use under Pandemic Conditions [PDF]

, 2008
On 3 October 2007, 40 participants with diverse expertise attended the workshop Tamiflu and the Environment: Implications of Use under Pandemic Conditions to assess the potential human health impact and environmental hazards associated with use of ...
Howard B. M., Saccà M. L., Boucard, Tatiana, Vouivoulis, N, Costigan S., Alistair Boxall, Costigan, S, John Churchley, Marsden P., Bird, S, Watts, Chris, Fick J., Johnson, Andrew C., Michael J. Dempsey, Bird S., Dempsey M. J., Knowles, CJ, Boucard, T, Townsend, Rodney, Jerker Fick, Straub, Jurg Oliver, Holmes J., Noone, Gerald, Voulvoulis N., Hutchinson T., Fick, J, Crane M., Maria Ludovica Saccà, Chubb C., Howard, BM, John Oxford, Voulvoulis, Nikolaos, Vouivoulis, Nikolaos, Cesare Accinelli, Noel Roberts, Peter Marsden, Barra Caracciolo A., Straub, JO, Kellher, Samuel L., Ellor, B, Boucard T., Cartmell, E, Sandra Costigan, Watts C., Sacca, Maria Ludovica, Roberts N., Noone, G, Hutchinson, Tom, Sanders M., Nunn, Miles A., John Holmes, Knowles, Chris J., Rodney Townsend, Simon Jackman, Chris Watts, Brian, Jayne V., Fick, Jerker, Marsden, Peter, Costigan, Sandra, Toovey, Stephen, Boxall, Alistair, Sanders, Matthew, Accinelli, C, Caracciolo, AB, Jackman, Simon, Marsden, P, Bob Dorrington, Accinelli, Cesare, Roberts, Noel, Stephen Bird, Bernard I, Sacca, ML, Chris J. Knowles, Jackman S., Dean Thomas, Jackman, S, Ellor, Brian, Karcher F., Bird, Stephen, Chris Chubb, Voulvoulis, N, Boxall A., Townsend, R, Howard, Bruce M., Sanders, M, Johnson A. C., Churchley, John, Dempsey, MJ, Andrew C. Johnson, Rachwal, T, Tatiana Boucard, Crane, Mark, Andrew C. Singer, Wells, Ursula, Terry A., Tony Rachwal, Jayne V. Brian, Stephen Toovey, Churchley, J, Miles A. Nunn, Dorrington, B, Toovey, S, Singer A. C., Dorrington B., Brian, JV, Thomas D., Toovey S., Dempsey, Michael J., Watts, C, Roberts M., Boxall, A, Tom Hutchinson, Matthew Sanders, Nikolaos Voulvoulis, Kelleher S. L., Roberts, Mike, Churchley J., Bernard, Ian, Townsend R., Cartmell, Elise, Franz Karcher, Karcher, Franz, Singer, Andrew C., Bruce M. Howard, Gerald Noone, Thomas, Dean, Nunn, MA, Anna Barra Caracciolo, Oxford J., Oxford, John, Holmes, J, Holmes, John, Churchley, J., Singer, AC, Jürg Oliver Straub, Hutchinson, T, Samuel L. Kelleher, Chubb, C, Boxall, Alastair, Knowles C. J., Nunn M. A., Mike Roberts, Oxford, J, Chubb, Chris, Rachwal, Tony, Bernard, I, Elise Cartmell, Dorrington, Bob, Thomas, D, Kelleher, SL, Brian J. V., Cartmell E., Rachwal T., Voulvoulis, Nick, Johnson, AC, Crane, M, Ian Bernard, Adrian Terry, Mark Crane, Caracciolo, Anna Barra, Roberts, M, Roberts, N, Straub J. O., Kelleher, Samuel L., Terry, Adrian, Noone G., Karcher, F, Wells U., Terry, A, Brian Ellor, Barra Caracciolo, Anna   +170 more
core   +1 more source

Comparative effectiveness of oseltamivir versus peramivir for hospitalized children (aged 0-5 years) with influenza infection

International Journal of Infectious Diseases, 2023
Objectives: The effectiveness of oseltamivir versus peramivir in children infected with influenza remains unclear. This study aimed to evaluate their effectiveness in young children (aged 0-5 years) infected with severe influenza A virus (IAV) or ...
Ming Xu, Ting Cai, Tingting Yue, Pan Zhang, Jie Huang, Qi Liu, Yue Wang, Ruping Luo, Zhengqiu Li, Linli Luo, Chunyi Ji, Xinrui Tan, Yanling Zheng, Richard Whitley, Erik De Clercq, Qiang Yin, Guangdi Li   +16 more
doaj   +1 more source

Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir. [PDF]

PLoS ONE, 2015
Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses.
Eun-Hye Hong, Jae-Hyoung Song, Aeri Shim, Bo-Ra Lee, Bo-Eun Kwon, Hyuk-Hwan Song, Yeon-Jeong Kim, Sun-Young Chang, Hyeon Gun Jeong, Jong Geal Kim, Sang-Uk Seo, HyunPyo Kim, YongSoo Kwon, Hyun-Jeong Ko   +13 more
doaj   +1 more source

Tracking oseltamivir-resistance in New Zealand influenza viruses during a medicine reclassification in 2007, a resistant-virus importation in 2008 and the 2009 pandemic

Western Pacific Surveillance and Response, 2012
Introduction: Oseltamivir (Tamiflu®) is an important pharmaceutical intervention against the influenza virus. The importance of surveillance for resistance to oseltamivir has been highlighted by two global events: the emergence of an oseltamivir ...
Richard J Hall, Matthew Peacey, Jacqui C Ralston, Danielle J de Joux, Judy Bocacao, Mackenzie Nicol, Molly Ziki, Wendy Gunn, Jing Wang, Q Sue Huang   +9 more
doaj   +1 more source

Systematic review and meta-analysis of the efficacy and safety of oseltamivir (Tamiflu) in the treatment of Coronavirus Disease 2019 (COVID-19).

PLoS ONE, 2022
Efforts are ongoing by researchers globally to develop new drugs or repurpose existing ones for treating COVID-19. Thus, this led to the use of oseltamivir, an antiviral drug used for treating influenza A and B viruses, as a trial drug for COVID-19 ...
Basiru Aliyu, Yakubu Egigogo Raji, Hui-Yee Chee, Mui-Yun Wong, Zamberi Bin Sekawi   +4 more
doaj   +2 more sources

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K., Geoff Pearson, Kathryn A Ryan, Newman, Edmund, Wendy S Barclay, Bean, Thomas J., Carroll, Miles W., Miles W Carroll, Brian K Dove, Bassam Hallis, Edmund Newman, Easton, A. J. (Andrew J.), Marriott, Anthony C., Hallis, Bassam, Whittaker, Catherine J., Dimmock, N. J., Stuart Dowall, Silman, Nigel J., Barclay, Wendy S., Rayner, Emma, Bruce, Christine, Taylor, Irene, Jenna Plank, Andrew J Easton, Pearson, Geoff, Catherine J Whittaker, Nigel J Silman, Christine Bruce, Ryan, Kathryn A., Nigel J Dimmock, Irene Taylor, Emma Rayner, Plank, Jenna, Anthony C Marriott, Dowall, Stuart, Thomas J Bean   +35 more
core   +1 more source

Acute Cheilitis Associated with Oseltamivir after Influenzae A Infection

Case Reports in Pediatrics, 2023
Oseltamivir is a neuraminidase inhibitor used to treat acute influenza A or B in adult and pediatric patients. Adverse reactions are usually mild. Here, we report novel side effects associated with oseltamivir.
Koji Yokoyama, Mitsukazu Mamada
doaj   +1 more source

The anti-influenza drug oseltamivir evokes hypothermia in mice through dopamine D2 receptor activation via central actions

Journal of Pharmacological Sciences, 2018
Oseltamivir has a hypothermic effect in mice when injected intraperitoneally (i.p.) and intracerebroventricularly (i.c.v.). Here we show that the hypothermia evoked by i.c.v.-oseltamivir is inhibited by non-selective dopamine receptor antagonists ...
Akihiro Fukushima, Arisa Fukui, Yuki Takemura, Yasuhiro Maeda, Hideki Ono   +4 more
doaj   +1 more source

Characteristics of Patients with Oseltamivir-Resistant Pandemic (H1N1) 2009, United States

Emerging Infectious Diseases, 2011
During April 2009–June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant.
Samuel B. Graitcer, Larisa Gubareva, Laurie Kamimoto, Saumil Doshi, Meredith Vandermeer, Janice Louie, Christine Waters, Zack Moore, Katrina Sleeman, Margaret Okomo-Adhiambo, Steven A. Marshall, Kirsten St. George, Chao-Yang Pan, Jennifer M. LaPlante, Alexander Klimov, Alicia M. Fry   +15 more
doaj   +1 more source

Simultaneous quantification of prodrug oseltamivir and its metabolite oseltamivir carboxylate in human plasma by LC–MS/MS to support a bioequivalence study

Journal of Pharmaceutical Analysis, 2013
A simple, precise and rapid liquid chromatography–tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the simultaneous determination of oseltamivir and oseltamivir carboxylate, a neuraminidase inhibitor, using their ...
Ajay Gupta, Swati Guttikar, Pranav S. Shrivastav, Mallika Sanyal   +3 more
doaj   +1 more source