Results 41 to 50 of about 25,524 (191)

Does C-reactive protein predict time to recovery and benefit from oseltamivir treatment in primary care patients with influenza-like illness? A randomized controlled trial secondary analysis

open access: yesScandinavian Journal of Primary Health Care, 2021
Objective Recovery time and treatment effect of oseltamivir in influenza-like illness (ILI) differs between patient groups. A point-of-care test to better predict ILI duration and identify patients who are most likely to benefit from oseltamivir ...
Nicolay Jonassen Harbin   +9 more
doaj   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed   +7 more
wiley   +1 more source

Oseltamivir-resistant pandemic (H1N1)2009 in Yemen - case report

open access: yesVirology Journal, 2010
Background During the influenza season of 2007-08, oseltamivir-resistant influenza A (H1N1) viruses emerged in several countries in Europe, North America, and Asia.
Al-Kohlani Abdulhakeem   +3 more
doaj   +1 more source

Comprehensive Performance Verification of the Mindray MN2880 System in Detecting Respiratory Virus Nucleic Acids

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study verified the analytical performance of the fully automated Mindray MN2880 system for the simultaneous detection of SARS‐CoV‐2, influenza A/B viruses, and RSV in 2852 oropharyngeal swab specimens, following CNAS‐GL039:2019, CNAS‐GL037:2019, and ISO 15189:2022 guidelines.
Jinliang Chen   +3 more
wiley   +1 more source

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza   +14 more
wiley   +1 more source

Time Economical Total Synthesis of (−)-Oseltamivir

open access: yes, 2016
A time economical 60 min total synthesis of (−)-oseltamivir was accomplished in a single reaction vessel over five steps. One of the key issues is reduction in the number of steps by eliminating lengthy reaction steps with substitution of a rapid ...
Shin Ogasawara (1831567)   +1 more
core   +1 more source

Efficacy of oseltamivir treatment in influenza virus-infected obese mice

open access: yesmBio, 2023
Obesity has been epidemiologically and empirically linked with more severe diseases upon influenza infection. To ameliorate severe disease, treatment with antivirals, such as the neuraminidase inhibitor oseltamivir, is suggested to begin within days of ...
Rebekah Honce   +10 more
doaj   +1 more source

Physiological and anatomical determinants of placental drug transfer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis   +3 more
wiley   +1 more source

Oseltamivir Treatment for Influenza During the Flu Season of 2018–2019: A Longitudinal Study

open access: yesFrontiers in Microbiology, 2022
BackgroundOseltamivir resistance in influenza virus (IFV) has been of widespread concern. An increase in the frequency of viruses with reduced inhibition was observed. Whether oseltamivir is effective is uncertain.
Xiao-Guang Li   +14 more
doaj   +1 more source

Severe Thrombocytopenia Induced by Re‐Exposure to Piperacillin/Tazobactam: A Case Report in Critically Ill Patient With COVID‐19

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Drug‐induced thrombocytopenia is a condition where certain medications can significantly reduce the platelets in the blood. This can increase the risk of bleeding and bruising. We reported a case of a 73‐year‐old woman with multiple comorbidities who was admitted to the hospital with COVID‐19.
Abdullah F. Alharthi   +6 more
wiley   +1 more source

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