Results 31 to 40 of about 42,609 (234)
Dear Editor, COVID-19 pandemics have been described in the city of Wuhan in China and spread around the world. The new type of SARS-Cov2, a mutant novel coronavirus that humans encountered for the first time, binds to ACE receptors cause pneumonia ...
Ömer Kutlu, A. Metin
semanticscholar +1 more source
Efforts are ongoing by researchers globally to develop new drugs or repurpose existing ones for treating COVID-19. Thus, this led to the use of oseltamivir, an antiviral drug used for treating influenza A and B viruses, as a trial drug for COVID-19 ...
Basiru Aliyu +4 more
doaj +2 more sources
Introduction: Oseltamivir (Tamiflu®) is an important pharmaceutical intervention against the influenza virus. The importance of surveillance for resistance to oseltamivir has been highlighted by two global events: the emergence of an oseltamivir ...
Q Sue Huang +9 more
doaj +1 more source
Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance [PDF]
Influenza viruses cause annual seasonal epidemics and occasional pandemics. It is important to elucidate the stringency of bottlenecks during transmission to shed light on mechanisms that underlie the evolution and propagation of antigenic drift, host ...
Ashcroft, J +12 more
core +1 more source
Oseltamivir Enhances Hippocampal Network Synchronization
Oseltamivir, a widely used anti-influenza drug, inhibits virus neuraminidase. A mammalian homologue of this enzyme is expressed in the brain, yet the effect of oseltamivir on central neurons is largely unknown.
Atsushi Usami +10 more
doaj +1 more source
Acute Cheilitis Associated with Oseltamivir after Influenzae A Infection
Oseltamivir is a neuraminidase inhibitor used to treat acute influenza A or B in adult and pediatric patients. Adverse reactions are usually mild. Here, we report novel side effects associated with oseltamivir.
Koji Yokoyama, Mitsukazu Mamada
doaj +1 more source
Characteristics of Patients with Oseltamivir-Resistant Pandemic (H1N1) 2009, United States
During April 2009–June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant.
Samuel B. Graitcer +15 more
doaj +1 more source
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children [PDF]
BACKGROUND: Neuraminidase inhibitors (NIs) are stockpiled and recommended by public health agencies for treating and preventing seasonal and pandemic influenza. They are used clinically worldwide.
Del Mar, Chris B. +11 more
core +1 more source
BACKGROUND A synergistic effect of combination therapy with favipiravir and oseltamivir has been reported in pre-clinical models of influenza. However, no data are available on the clinical effectiveness of combination therapy in severe influenza ...
Ye-ming Wang +11 more
semanticscholar +1 more source
Oseltamivir has a hypothermic effect in mice when injected intraperitoneally (i.p.) and intracerebroventricularly (i.c.v.). Here we show that the hypothermia evoked by i.c.v.-oseltamivir is inhibited by non-selective dopamine receptor antagonists ...
Akihiro Fukushima +4 more
doaj +1 more source

