Results 41 to 50 of about 42,609 (234)

Simultaneous quantification of prodrug oseltamivir and its metabolite oseltamivir carboxylate in human plasma by LC–MS/MS to support a bioequivalence study

Journal of Pharmaceutical Analysis, 2013
A simple, precise and rapid liquid chromatography–tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the simultaneous determination of oseltamivir and oseltamivir carboxylate, a neuraminidase inhibitor, using their ...
Ajay Gupta, Swati Guttikar, Pranav S. Shrivastav, Mallika Sanyal   +3 more
doaj   +1 more source

Oseltamivir (Tamiflu®)-induced pneumonia [PDF]

, 2008
SummaryWe report the first case of oseltamivir-induced pneumonia. A 50-year-old man was diagnosed with influenza and prescribed oseltamivir. He had a persistent high fever, and developed a productive cough with peripheral blood eosinophilia and his chest
Iwata, Yasuhiro, Nagata, Nobuhiko, Wakamatsu, Kentaro, Matsunaga, Kazuko, Kumazoe, Hiroyuki, Komori, Masashi, Kajiki, Akira, Kitahara, Yoshinari   +7 more
core   +1 more source

Effect of early oseltamivir on outpatients without hypoxia with suspected COVID-19

Wiener Klinische Wochenschrift, 2020
Since December 2019 coronavirus disease 2019 (COVID-19) outbreaks have occurred in China and many countries around the world. The effectiveness of oseltamivir on COVID-19 suspected outpatients without hypoxia was evaluated.
S. Chiba
semanticscholar   +1 more source

Exacerbation of neuropsychiatric symptoms in an adult male with influenza A virus treated with oseltamivir [PDF]

Mental Health Clinician
Oseltamivir (Tamiflu) package labeling has a warning for neuropsychiatric adverse events (NPAE), most commonly in children and adolescents, especially males.
Masa Scott, PharmD, BCPS, BCPP, Emily Faltin, PharmD, MBA, Kathleen Londick, PharmD   +2 more
doaj   +1 more source

A Phase 2 Study of Pimodivir (JNJ-63623872) in Combination With Oseltamivir in Elderly and Nonelderly Adults Hospitalized With Influenza A Infection: OPAL Study

Journal of Infectious Diseases, 2020
Background Both the elderly and individuals with comorbidities are at increased risk of developing influenza-related complications. Novel influenza antivirals are required, given limitations of current drugs (eg, resistance emergence and poor efficacy ...
B. O’Neil, M. Ison, M. Hallouin-Bernard, A. Nilsson, A. Torres, J. Wilburn, Wilbert van Duijnhoven, Ilse van Dromme, David Anderson, S. Deleu, T. Kosoglou, J. Vingerhoets, S. Rossenu, L. Leopold   +13 more
semanticscholar   +1 more source

Combinatory Treatment with Oseltamivir and Itraconazole Targeting Both Virus and Host Factors in Influenza A Virus Infection

Viruses, 2020
Influenza virus infections and their associated morbidity and mortality are a major threat to global health. Vaccination is an effective influenza prevention measure; however, the effectiveness is challenged by the rapid changes in the influenza virus ...
S. Schloer, J. Goretzko, S. Pleschka, S. Ludwig, U. Rescher   +4 more
semanticscholar   +1 more source

Efficacy of baloxavir marboxil on household transmission of influenza infection

Journal of Pharmaceutical Health Care and Sciences, 2020
Background Baloxavir marboxil (baloxavir) is a new anti-influenza virus agent that is comparable to oseltamivir phosphate (oseltamivir). Since the efficacy of baloxavir in preventing household transmission of influenza is not well established, we ...
Takumi Umemura, Yoshikazu Mutoh, Takato Kawamura, Masayuki Saito, Takahito Mizuno, Aiko Ota, Koji Kozaki, Tetsuya Yamada, Yoshiaki Ikeda, Toshihiko Ichihara   +9 more
doaj   +1 more source

Deletions in the neuraminidase stalk region of H2N2 and H9N2 avian influenza virus subtypes do not affect postinfluenza secondary bacterial pneumonia [PDF]

, 2012
We investigated the synergism between influenza virus and Streptococcus pneumoniae, particularly the role of deletions in the stalk region of the neuraminidase (NA) of H2N2 and H9N2 avian influenza viruses.
Chen, Hongjun, Chockalingam, Ashok K., Echenique, Jose Ricardo, Ferrero, Andrea, Hickman, Danielle, Pena, Lindomar, Perez, Daniel R., Sutton, Troy, Ye, Jianqiang   +8 more
core   +1 more source

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]

, 2012
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Dyason, JC, Kerry, Philip Stephen, Naffakh, N, Rameix-Welti, MA, Rose, FJ, Rudrawar, S, Russell, Rupert James Martin, Thomson, RJ, van der Werf, S, von Itzstein, M   +9 more
core   +1 more source

Efficacy of clarithromycin-naproxen-oseltamivir combination therapy versus oseltamivir alone in hospitalized pediatric influenza patients.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2020
PURPOSE This study aimed to compare the safety and efficacy of clarithromycin-naproxen-oseltamivir combination therapy to that of oseltamivir therapy alone in hospitalized pediatric influenza patients.
Chien-Wei Lee, Yu-Lin Tai, Li-Min Huang, H. Chi, F. Huang, N. Chiu, Ching-Ying Huang, Yi-Hsuan Tu, Jin-Yuan Wang, Daniel Tsung-Ning Huang   +9 more
semanticscholar   +1 more source