Results 161 to 170 of about 87,991 (243)

Transcriptional plasticity of stromal cells amplifies their differentiation efficiency in vitro. [PDF]

J Biol Chem
Jamil AJM, Nørgård MØ, Grupe E, Rauch A.   +3 more
europepmc   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

DEC1 regulates osteoblast proliferation and differentiation via the RUNX2 signaling pathway: Insights into the molecular mechanism of DEC1-mediated transcriptional regulation in bone metabolism. [PDF]

Open Life Sci
Qian W, Mei K, Zhu L, Lv J, Yun C.
europepmc   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

Selective deletion of the membrane-bound isoform of CSF1 in vivo augments the anabolic response to PTH without impairing bone resorption. [PDF]

Bone Rep
Yao GQ, Zhu M, Insogna K.
europepmc   +1 more source

Osteoblast Lineage

, 1998
Triffitt, J, Oreffo, R
openaire   +2 more sources

Biofilm removal capacity and titanium surface integrity in non‐abrasive versus abrasive peri‐implantitis cleaning interventions

Journal of Periodontology, EarlyView.
Abstract Background Current peri‐implantitis treatment methods are modeled after dental cleaning modalities like abrasive surface cleaning. However, mechanical abrasive cleaning not only inadequately removes implant biofilms but also compromises implant surface integrity with adverse biological effects.
Marzieh S. Jazaeri, Danyal A. Siddiqui, Yi‐Wen C. Tsai, Kathryn Gabel, Zachary Lorenzana, Georgios A. Kotsakis   +5 more
wiley   +1 more source

mTOR signalling mediates the spinal osteoblast pathotype at the curve apex in adolescent idiopathic scoliosis

Northall EH, Nicholson TA, Hazeldine J, Grover LM, McGettrick HM, Ede MN, Naylor AJ, Jones SW.   +7 more
europepmc   +1 more source