Results 191 to 200 of about 197,424 (329)

ABS0148 PAR2 DELETION IN THE OSTEOBLAST LINEAGE AFFORDS LONG-TERM CARTILAGE PROTECTION IN EXPERIMENTAL OSTEOARTHRITIS

Carmen Huesa, Sarah McGrath, L. Dunning, M Vieri, Kendal McCulloch, Kenneth McIntosh, Jack W. Cole, Robin Plevin, Daniel J. Rowan, Rebecca Hof, W.R. Ferrell, JC Lockhart, Carl S. Goodyear   +12 more
openalex   +1 more source

Alendronate promotes osteoblast differentiation and bone formation in ovariectomy‑induced osteoporosis through interferon‑β/signal transducer and activator of transcription 1 pathway

, 2017
Xiaoqing Ma, Zhongyang Xu, Shaofeng Ding, Guangkun Yi, Qian Wang   +4 more
openalex   +2 more sources

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Targeting integrin αVβ3-Ptgs2-mTOR signaling rescues bone formation in osteoporosis: from molecular mechanism toward therapy. [PDF]

Cell Mol Biol Lett
Chen C, Gu J, Yang C, Yang F, Liu Z, Wen L, Chen R, Geng B, Xia Y.   +8 more
europepmc   +1 more source

Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner [PDF]

, 2017
Soohyun P. Kim, Zhu Li, Meredith L. Zoch, Julie L. Frey, Caitlyn E. Bowman, Priyanka Kushwaha, Kathleen A. Ryan, Brian C. Goh, Susanna Scafidi, Julie E. Pickett, Marie–Claude Faugere, Erin E. Kershaw, Daniel L.J. Thorek, Thomas L. Clemens, Michael J. Wolfgang, Ryan C. Riddle   +15 more
openalex   +1 more source

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation

Advanced Science, EarlyView.
A hyaluronic acid methacrylate (HAMA) hydrogel incorporating DNA tetrahedrons loaded with Asiatic acid (TDN@AA) was developed. HM‐TDN@AA promotes angiogenesis of endothelial cells (ECs), inhibits osteoclastogenesis from bone marrow–derived macrophages (BMDMs), and enhances osteogenesis of mesenchymal stem cells (MSCs) via STAT3‐mediated mitochondrial ...
Yiwen Huang, Yiming Zhang, Yisheng Feng, Qixiang Yang, Beiyuan Gao, Haiyang Xu, Cheng Huang, Kaili Lin, Yuanzhi Xu, Peiqi Zhu   +9 more
wiley   +1 more source

Expression of Concern: Enhancement of Differentiation and Mineralisation of Osteoblast-like Cells by Degenerate Electrical Waveform in an In Vitro Electrical Stimulation Model Compared to Capacitive Coupling. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development [PDF]

, 2015
Xuchen Duan, Yurie Murata, Yanqiu Liu, Claudia M. Nicolae, Bjørn R. Olsen, Agnes D. Berendsen   +5 more
openalex   +1 more source

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review). [PDF]

Int J Mol Med
Cui RM, Zheng M, Hong JB, Wang ZX, Cun YF, Gao SJ, Zhu YL, Yang ZB, Liu MW.   +8 more
europepmc   +1 more source