Results 1 to 10 of about 82,399 (140)

Effect of rosmarinic acid on differentiation and mineralization of MC3T3-E1 osteoblastic cells on titanium surface [PDF]

open access: yesAnimal Cells and Systems, 2021
Titanium (Ti) is a widely used biomaterial for dental implants because of its outstanding biocompatibility for hard tissues. Osseointegration, the interaction between implanted biomaterials and living cells in bone, is essential for successful ...
Moon-Jin Jeong   +5 more
doaj   +2 more sources

Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli [PDF]

open access: yes, 2017
Stem cell fate has been linked to the mechanical properties of their underlying substrate, affecting mechanoreceptors and ultimately leading to downstream biological response.
Boyan, Barbara D.   +8 more
core   +21 more sources

Enhanced osteogenic differentiation in zoledronate-treated osteoporotic patients [PDF]

open access: yes, 2017
Bisphosphonates are well known inhibitors of osteoclast activity and thus may be employed to influence osteoblast activity. The present study was designed to evaluate the in vivo effects of zoledronic acid (ZA) on the proliferation and osteoblastic ...
Carbonare, Luca Dalle   +7 more
core   +9 more sources

OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling. [PDF]

open access: yesPLoS ONE, 2016
Excessive dexamethasone (Dex) application causes osteoblast cell death, which could lead to osteoporosis or osteonecrosis. AMP-activated protein kinase (AMPK) activation is shown to protect osteoblasts/osteoblastic cells from Dex.
Dawei Xu   +8 more
doaj   +1 more source

Interplay between Cultured Human Osteoblastic and Skeletal Muscle Cells: Effects of Conditioned Media on Glucose and Fatty Acid Metabolism

open access: yesBiomedicines, 2023
The interplay between skeletal muscle and bone is primarily mechanical; however, biochemical crosstalk by secreted mediators has recently gained increased attention.
Ngoc Nguyen Lunde   +9 more
doaj   +1 more source

Cold atmospheric plasma enhances osteoblast differentiation. [PDF]

open access: yesPLoS ONE, 2017
This study was designed to assess the effects of cold atmospheric plasma on osteoblastic differentiation in pre-osteoblastic MC3T3-E1 cells. Plasma was irradiated directly to a culture medium containing plated cells for 5 s or 10 s. Alkaline phosphatase (
Kanako Tominami   +5 more
doaj   +1 more source

Biocompatibility and Cellular Behavior of TiNbTa Alloy with Adapted Rigidity for the Replacement of Bone Tissue

open access: yesMetals, 2021
In this work, the mechanical and bio-functional behavior of a TiNbTa alloy is evaluated as a potential prosthetic biomaterial used for cortical bone replacement. The results are compared with the reference Ti c.p.
Mercè Giner   +9 more
doaj   +1 more source

The role of cells and signal pathways in subchondral bone in osteoarthritis

open access: yesBone & Joint Research, 2023
Osteoarthritis (OA) is mainly caused by ageing, strain, trauma, and congenital joint abnormalities, resulting in articular cartilage degeneration. During the pathogenesis of OA, the changes in subchondral bone (SB) are not only secondary manifestations ...
Pan Luo   +4 more
doaj   +1 more source

Neural Cell Adhesion Molecule Regulates Osteoblastic Differentiation Through Wnt/β-Catenin and PI3K-Akt Signaling Pathways in MC3T3-E1 Cells

open access: yesFrontiers in Endocrinology, 2021
Neural cell adhesion molecule (NCAM) is involved in cell multi-directional differentiation, but its role in osteoblast differentiation is still poorly understood.
Bin-Feng Cheng   +10 more
doaj   +1 more source

Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro

open access: yesJournal of Dental Sciences, 2023
Background/purpose: The mineralized tissue-inductive ability and anti-inflammatory properties of hydraulic calcium silicate-based (HCSB) sealers have not been fully elucidated.
Aseel Alchawoosh   +5 more
doaj   +1 more source

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