Results 1 to 10 of about 81,269 (285)

Effect of rosmarinic acid on differentiation and mineralization of MC3T3-E1 osteoblastic cells on titanium surface [PDF]

Animal Cells and Systems, 2021
Titanium (Ti) is a widely used biomaterial for dental implants because of its outstanding biocompatibility for hard tissues. Osseointegration, the interaction between implanted biomaterials and living cells in bone, is essential for successful ...
Moon-Jin Jeong, Do-Seon Lim, Sung Ok Kim, Cheol Park, Yung Hyun Choi, Soon-Jeong Jeong   +5 more
doaj   +2 more sources

Interplay between Cultured Human Osteoblastic and Skeletal Muscle Cells: Effects of Conditioned Media on Glucose and Fatty Acid Metabolism

Biomedicines, 2023
The interplay between skeletal muscle and bone is primarily mechanical; however, biochemical crosstalk by secreted mediators has recently gained increased attention.
Ngoc Nguyen Lunde, Nimo Mukhtar Mohamud Osoble, Andrea Dalmao Fernandez, Alfreda S. Antobreh, Abbas Jafari, Sachin Singh, Tuula A. Nyman, Arild C. Rustan, Rigmor Solberg, G. Hege Thoresen   +9 more
doaj   +1 more source

Cold atmospheric plasma enhances osteoblast differentiation. [PDF]

PLoS ONE, 2017
This study was designed to assess the effects of cold atmospheric plasma on osteoblastic differentiation in pre-osteoblastic MC3T3-E1 cells. Plasma was irradiated directly to a culture medium containing plated cells for 5 s or 10 s. Alkaline phosphatase (
Kanako Tominami, Hiroyasu Kanetaka, Shota Sasaki, Takayuki Mokudai, Toshiro Kaneko, Yoshimi Niwano   +5 more
doaj   +1 more source

Biocompatibility and Cellular Behavior of TiNbTa Alloy with Adapted Rigidity for the Replacement of Bone Tissue

Metals, 2021
In this work, the mechanical and bio-functional behavior of a TiNbTa alloy is evaluated as a potential prosthetic biomaterial used for cortical bone replacement. The results are compared with the reference Ti c.p.
Mercè Giner, Ernesto Chicardi, Alzenira de Fátima Costa, Laura Santana, María Ángeles Vázquez-Gámez, Cristina García-Garrido, Miguel Angel Colmenero, Francisco Jesús Olmo-Montes, Yadir Torres, María José Montoya-García   +9 more
doaj   +1 more source

The role of cells and signal pathways in subchondral bone in osteoarthritis

Bone & Joint Research, 2023
Osteoarthritis (OA) is mainly caused by ageing, strain, trauma, and congenital joint abnormalities, resulting in articular cartilage degeneration. During the pathogenesis of OA, the changes in subchondral bone (SB) are not only secondary manifestations ...
Pan Luo, Qi-ling Yuan, Mingyi Yang, Xianjie Wan, Peng Xu   +4 more
doaj   +1 more source

Osteoblasts as leukemia-initiating cells [PDF]

BoneKEy Reports, 2014
Commentary on: Kode A, Manavalan JS, Mosialou I, Bhagat G, Rathinam CV, Luo N, Khiabanian H, Lee A, Murty VV, Friedman R, Brum A, Park D, Galili N, Mukherjee S, Teruya-Feldstein J, Raza A, Rabadan R, Berman E, Kousteni S. Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts. Nature 2014;506(7487):240–244. Hematopoietic stem and
Benjamin J, Frisch, Laura M, Calvi
openaire   +2 more sources

Neural Cell Adhesion Molecule Regulates Osteoblastic Differentiation Through Wnt/β-Catenin and PI3K-Akt Signaling Pathways in MC3T3-E1 Cells

Frontiers in Endocrinology, 2021
Neural cell adhesion molecule (NCAM) is involved in cell multi-directional differentiation, but its role in osteoblast differentiation is still poorly understood.
Bin-Feng Cheng, Xiao Feng, Yao-Xin Gao, Shao-Qin Jian, Shi-Rao Liu, Mian Wang, Yun-Fei Xie, Lei Wang, Zhi-Wei Feng, Hai-Jie Yang, Hai-Jie Yang   +10 more
doaj   +1 more source

Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro

Journal of Dental Sciences, 2023
Background/purpose: The mineralized tissue-inductive ability and anti-inflammatory properties of hydraulic calcium silicate-based (HCSB) sealers have not been fully elucidated.
Aseel Alchawoosh, Kentaro Hashimoto, Nobuyuki Kawashima, Sonoko Noda, Kosuke Nozaki, Takashi Okiji   +5 more
doaj   +1 more source

Antagonizing exosomal miR-18a-5p derived from prostate cancer cells ameliorates metastasis-induced osteoblastic lesions by targeting Hist1h2bc and activating Wnt/β-catenin pathway

Genes and Diseases, 2023
More than 50% of prostate cancer (PCa) patients have bone metastasis with osteoblastic lesions. MiR-18a-5p is associated with the development and metastasis of PCa, but it remains unclear whether it is involved in osteoblastic lesions.
Fanchun Zeng, Chunrong Zhao, Rujie Wang, Lingyan Ren, Hao Qiu, Zhi Zou, Haibin Ding, Zhongyi Sun, Jianmei Li, Shiwu Dong   +9 more
doaj   +1 more source

Downregulation of miR-184 facilitates osseous differentiation in periodontal ligament stem cells by modulating nuclear factor I-C

Journal of Dental Sciences, 2021
Background/purpose: PDLSCs (periodontal ligament stem cells), derived from dental tissues, are candidate cells for regeneration of dental tissues. MiRNAs could regulate osteogenic differentiation and the transformation into osteoblasts.
Chunying Li, Guanglin Duan, Yaopu Feng
doaj   +1 more source