, 2017 Click on the DOI link to access the article (may not be free).BACKGROUND CONTEXT: Stem cell-involved tissue engineering has gained dramatic attention as a therapeutic strategy for tissue regeneration including bone repair.
Gong, Xuan +3 more
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Materials Research, 2013 Nanocomposites based on superhydrophilic vertically aligned multi-walled carbon nanotubes (VAMWCNT-O2) and nanohydroxyapatite (nHAp) are of great interest in bone regenerative medicine.
Marcele Florencio Neves +5 more
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In vitro and in vivo characterization of murine bone marrow stromal stem cells: self renewal, differentiation, tumorigenic potential [PDF]
, 2009 The use of adult stem cells for applications such as tissue engineering and gene therapy is one of the major challenge approaches of regenerative medicine. In the field of adult stem cells, bone marrow stromal cells (BMSCs) are very promising candidates.
Esposito, Maria Teresa
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Platelet lysate as a serum substitute for 2D static and 3D perfusion culture of stromal vascular fraction cells from human adipose tissue [PDF]
, 2009 Fetal bovine serum (FBS) and fibroblast growth factor (FGF)-2 are key supplements for the culture of stromal vascular fraction (SVF) cells from adipose tissue, both for typical monolayer (2D) expansion and for streamlined generation of osteogenic ...
Alini, Mauro +8 more
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Biological Research, 2015 BACKGROUND: Mechanical strain plays a great role in growth and differentiation of osteoblast. A previous study indicated that integrin-β (β1, β5) mediated osteoblast proliferation promoted by mechanical tensile strain.
Qiangcheng Zeng +8 more
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Transcriptional program of osteoblast differentiation : coordinated activation of Notch, Wnt, and TGF-[beta] signaling pathways in MC3T3 cell line [PDF]
, 2005 In order to examine the early events in osteoblast differentiation, three different model systems for osteoblast differentiation were compared: mouse pre-osteoblastic cell line MC3T3; mouse myoblastic cell line C2C12 and primary mouse calvarial ...
Zamurovic, Natasa
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CCN1 induces oncostatin M production in osteoblasts via integrin-dependent signal pathways.
PLoS ONE, 2014 Inflammatory response and articular destruction are common symptoms of osteoarthritis. Cysteine-rich 61 (CCN1 or Cyr61), a secreted protein from the CCN family, is associated with the extracellular matrix involved in many cellular activities like growth ...
Cheng-Yu Chen +5 more
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Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells [PDF]
, 2010 Human skeletal stem cells (STRO-1 positive/STRO-1+) respond to different topographical features in various ways. On a flat surface these cells spread and tend to develop a fibroblast-like morphology.
Burgess, K.E.V. +15 more
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Protein Phosphatase 2A Mediates Oxidative Stress Induced Apoptosis in Osteoblasts
Mediators of Inflammation, 2015 Osteoporosis is one of the most common bone diseases, which is characterized by a systemic impairment of bone mass and fragility fractures. Age-related oxidative stress is highly associated with impaired osteoblastic dysfunctions and subsequent ...
Chong-xin Huang, Bo Lv, Yue Wang
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Genistein modulates the effects of parathyroid hormone in human osteoblastic SaOS-2 cells
, 2006 Genistein and parathyroid hormone (PTH) are anabolic agents that stimulate bone formation through their direct actions in osteoblastic cells. In the present study, we aimed to determine whether genistein modulates the actions of PTH in human osteoblastic
Man-Sau Wong +3 more
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