Results 91 to 100 of about 894,587 (193)

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation

Scientific Reports, 2019
Targeting regulatory signaling pathways that control human bone marrow stromal (skeletal or mesenchymal) stem cell (hBMSC) differentiation and lineage fate determination is gaining momentum in the regenerative medicine field.
Mona Elsafadi, Tasneem Shinwari, Sami Al-Malki, Muthurangan Manikandan, Amer Mahmood, Abdullah Aldahmash, Musaad Alfayez, Moustapha Kassem, Nehad M. Alajez   +8 more
doaj   +1 more source

Platelet-released supernatant induces osteoblastic differentiation of human mesenchymal stem cells: potential role of BMP-2 [PDF]

European Cells & Materials, 2010
Platelet-rich preparations have recently gained popularity in maxillofacial and dental surgery, but their beneficial effect is still under debate. Furthermore, very little is known about the effect of platelet preparations at the cellular level, and the ...
M Alini, P Heini, T Stol, TR Meury, L Kupcsik, S Verrier   +5 more
doaj  

Osteoblastic Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth by Probiotic Hydroxyapatite. [PDF]

Cell J, 2023
Nouri S, Roghanian R, Emtiazi G, Gunduz O, Shafiei R.   +4 more
europepmc   +1 more source

Understanding the functional role of genistein in the bone differentiation in mouse osteoblastic cell line MC3T3-E1 by RNA-seq analysis

, 2018
Genistein, a phyto-estrogen, can potentially replace endogenous estrogens in postmenopausal women, but the underlying molecular mechanisms remain incompletely understood.
Yoon Shin Cho, Suji Kim, Myungsuk Kim, Jisun Lim, Chu Won Nho, Kye Won Park, Jung-Hee Lee, Kyung-Mi Lee   +7 more
core   +1 more source

Alpha-adrenergic blocker mediated osteoblastic stem cell differentiation

, 2017
Recent researches have indicated a role for antihypertensive drugs including alpha- or beta-blockers in the prevention of bone loss. Some epidemiological studies reported the protective effects of those agents on fracture risk.
이승진
core   +1 more source

Enhanced osteoblastic differentiation of parietal bone in a novel murine model of mucopolysaccharidosis type II. [PDF]

Mol Genet Metab Rep, 2023
Yamazaki N, Ohira M, Takada S, Ohtake A, Onodera M, Nakanishi M, Okuyama T, Mashima R.   +7 more
europepmc   +1 more source

Melatonin Promotes BMSCs Osteoblastic Differentiation and Relieves Inflammation by Suppressing the NF-κB Pathways. [PDF]

Stem Cells Int, 2023
Hu Y, Xiong Y, Zha K, Tao R, Chen L, Xue H, Yan C, Lin Z, Endo Y, Cao F, Zhou W, Liu G.   +11 more
europepmc   +1 more source

MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivo

Journal of Translational Medicine
Background MicroRNAs (miRNAs) play a crucial role in cell differentiation through epigenetic regulation of gene expression. In human dental pulp cells, we have identified miRNA-27a being upregulated under inflammatory conditions.
Ziniu Yu, Nobuyuki Kawashima, Keisuke Sunada-Nara, Shihan Wang, Peifeng Han, Thoai Quoc Kieu, Chunmei Ren, Sonoko Noda, Kento Tazawa, Takashi Okiji   +9 more
doaj   +1 more source

Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling. [PDF]

Cell Death Dis, 2023
Quarato ER, Salama NA, Li AJ, Smith CO, Zhang J, Kawano Y, McArthur M, Liesveld JL, Becker MW, Elliott MR, Eliseev RA, Calvi LM.   +11 more
europepmc   +1 more source

The role of chemistry and strut porosity and the influence of serum proteins in modulating cellular response to bone graft substitutes [PDF]

, 2015
The objective of this thesis was to investigate the role of hydroxyapatite and silicate-substituted hydroxyapatite synthetic bone graft substitute (SBG) material properties in modulating the processes of protein adsorption and desorption, and their ...
Castagna, Viviana
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