Vascular calcification significantly elevates cardiovascular risk in CKD patients, yet no effective therapies exist to halt its progression. We developed a dual targeting nanoplatform Ti3C2/RANKL/OCN/Cyanidin (TROC) for the targeted delivery of cyanidin against vascular calcification.
Li Yin +10 more
wiley +1 more source
Repopulation of a 3D simulated periapical lesion cavity with dental pulp stem cell spheroids with triggered osteoblastic differentiation. [PDF]
Ribeiro VL +8 more
europepmc +1 more source
CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma. [PDF]
Yan X, Kang D, Lin Y, Qi S, Jiang C.
europepmc +1 more source
Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats
ABSTRACT Aim This study aimed to investigate the effects of copaiba oil–resin on induced apical periodontitis in rats. Methodology A total of 24 male Wistar rats were divided equally into three groups (eight animals each): control (C), apical periodontitis (AP) and apical periodontitis with copaiba administration (AP + COP).
Rayssa Maitê Farias Nazário +11 more
wiley +1 more source
Thrombospondin-1 Silencing Ameliorates Osteoblastic Differentiation of Aortic Valve Interstitial Cells via Inhibiting Nuclear Factor-<i>κ</i>B Pathway. [PDF]
Li Q +9 more
europepmc +1 more source
Spherical bioactive glass nanoparticles containing strontium inhibit osteoclast differentiation and activity, but promote osteoblast activity in osteoblast‐osteoclast in vitro co‐culture. The nanoparticles could be used for the treatment of osteoporosis.
Parichart Naruphontjirakul +2 more
wiley +1 more source
Reducing PDK4 level constitutes a pivotal mechanism for glucocorticoids to impede osteoblastic differentiation through the enhancement of ferroptosis in mesenchymal stem cells. [PDF]
Jiang Y +11 more
europepmc +1 more source
E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR. [PDF]
Pham T, Najy AJ, Kim HC.
europepmc +1 more source
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang +27 more
wiley +1 more source

