Results 1 to 10 of about 31,358 (262)

Effect of diabetic osteoblasts on osteogenic differentiation of human umbilical cord mesenchymal stem cells [PDF]

open access: goldBiomedical Papers, 2015
Background: This study was aimed to investigate whether osteoblasts from diabetic patients have a promoting effect on osteogenesis of human umbilical cord mesenchymal stem cells (HUMSCs).
Ha Cheng-Zhi   +9 more
doaj   +2 more sources

Substrate Stiffness of Bone Microenvironment Controls Functions of Pre-Osteoblasts and Fibroblasts In Vitro

open access: yesBiomimetics, 2023
The formation of bone in a bone defect is accomplished by osteoblasts, while the over activation of fibroblasts promotes fibrosis. However, it is not clear how the extracellular matrix stiffness of the bone-regeneration microenvironment affects the ...
Shenghan Gao   +6 more
doaj   +1 more source

Nrf2 signaling activation by a small molecule activator compound 16 inhibits hydrogen peroxide-induced oxidative injury and death in osteoblasts

open access: yesCell Death Discovery, 2022
We explored the potential activity of compound 16 (Cpd16), a novel small molecule Nrf2 activator, in hydrogen peroxide (H2O2)-stimulated osteoblasts. In the primary murine/human osteoblasts and MC3T3-E1 murine osteoblastic cells, Cpd16 treatment at micro-
Jing-wei Zhao   +6 more
doaj   +1 more source

Rifampicin restores extracellular organic matrix formation and mineralization of osteoblasts after intracellular Staphylococcus aureus infection

open access: yesBone & Joint Research, 2022
Aims: Bone regeneration during treatment of staphylococcal bone infection is challenging due to the ability of Staphylococcus aureus to invade and persist within osteoblasts.
Francisca I. Alagboso   +6 more
doaj   +1 more source

Osteoblast-Osteoclast Communication and Bone Homeostasis

open access: yesCells, 2020
Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate with each other to regulate cellular behavior, survival and differentiation through direct cell ...
Jung-Min Kim   +4 more
doaj   +1 more source

Biosafety of 3D printed titanium alloy porous materials to osteoblast cell line MC3T3-E1 [PDF]

open access: yesJichu yixue yu linchuang, 2020
Objective To prepare 3D-printed porous materials of titanium alloy by electron beaming melting (EBM) and to confirm its biosafety to osteoblasts (OB). Methods Three topological structures of titanium alloy porous materials (2.0 mm, 2.25 mm and 2.5 mm ...
JING Li, SHI Wen, CAO Yu, LIU Rui-sai, LIU Lu, LI Jian-yu, LIU Hui
doaj  

Expression of mRNA for 5-HT2 Receptors and Proteins Related to Inactivation of 5-HT in Mouse Osteoblasts

open access: yesJournal of Pharmacological Sciences, 2009
We analyzed the expression of 5-HT2 receptors and proteins related to inactivation of 5-HT in primary cultures of mouse osteoblasts. The mRNA for the 5-HT2A receptor was detectable in anaplastic osteoblasts as well as in differentiated and matured ...
Takao Hirai   +3 more
doaj   +1 more source

Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment

open access: yesBreast Cancer Research, 2020
Background Osteoclast activation is a hallmark of breast cancer-induced bone disease while little is known about the role of osteoblasts in this process.
Marie-Therese Haider   +9 more
doaj   +1 more source

Effects of Mechanical Stress Stimulation on Function and Expression Mechanism of Osteoblasts

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and osteogenic activities.
Pan Liu   +11 more
doaj   +1 more source

DKK1 Induced by 1,25D3 Is Required for the Mineralization of Osteoblasts

open access: yesCells, 2020
1α,25-dihydroxyvitamin D3 (1,25D3), the most popular drug for osteoporosis treatment, drives osteoblast differentiation and bone mineralization. Wnt/β-catenin signaling is involved in commitment and differentiation of osteoblasts, but the role ...
Sungsin Jo   +9 more
doaj   +1 more source

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