Regulation of Cytoplasmic pH in Osteoclasts [PDF]
Tommy Nordström+7 more
openalex +1 more source
Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm+18 more
wiley +1 more source
Licochalcone D inhibits osteoclast differentiation and postmenopausal osteoporosis by inactivating the NF-κB signaling pathway. [PDF]
Shen X+7 more
europepmc +1 more source
Human osteoclast and giant cell differentiation: the apparent switch from nonspecific esterase to tartrate resistant acid phosphatase activity coincides with the in situ expression of osteopontin mRNA. [PDF]
J.R. Connor+3 more
openalex +1 more source
Expert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis
Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G. Saag
wiley +1 more source
Cathepsin B and L activities in isolated osteoclasts
Barry R. Rifkin+5 more
openalex +1 more source
Initiation of Osteoclast Bone Resorption by Interstitial Collagenase [PDF]
L. Shannon Holliday+5 more
openalex +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Female Mice Lacking LSD1 in Myeloid Cells Are Resistant to Inflammatory Bone Loss. [PDF]
Astleford-Hopper K+9 more
europepmc +1 more source