Results 261 to 270 of about 129,093 (305)
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Glucocorticoids and the Osteoclast
Annals of the New York Academy of Sciences, 2007Abstract: Glucocorticoid (GC)‐induced bone loss is the most common cause of secondary osteoporosis but its pathogenesis is controversial. GCs clearly suppress bone formation in vivo but the means by which they impact osteoblasts is unclear. Because bone remodeling is characterized by tethering of the activities of the two cells, the osteoclast is a ...
Hyun-Ju, Kim +7 more
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Annals of the New York Academy of Sciences, 2010
Thirty‐five years ago it had become clear that the osteoclast was not a bone cell but an immigrant into bone, derived from the hemopoietic system. Among hemopoietic cells, mononuclear phagocytes seemed the most likely precursors. However, for the progeny of wandering cells such as those to achieve nonrandom localization implies control by the local ...
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Thirty‐five years ago it had become clear that the osteoclast was not a bone cell but an immigrant into bone, derived from the hemopoietic system. Among hemopoietic cells, mononuclear phagocytes seemed the most likely precursors. However, for the progeny of wandering cells such as those to achieve nonrandom localization implies control by the local ...
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Journal of Dental Research, 1966
SYNOPSIS IN INTERLINGUA HISTOGENESE DE OSTEOCLASTAS.— Rattos blanc esseva subjicite a duo injectiones de 200 unitates de Parathormon con un intervallo de 12 horas. Tres horas post le prime injection, thymidina a tritium esseva administrate.
P D, Toto, J J, Magon
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SYNOPSIS IN INTERLINGUA HISTOGENESE DE OSTEOCLASTAS.— Rattos blanc esseva subjicite a duo injectiones de 200 unitates de Parathormon con un intervallo de 12 horas. Tres horas post le prime injection, thymidina a tritium esseva administrate.
P D, Toto, J J, Magon
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Long bone osteoclasts display an augmented osteoclast phenotype compared to calvarial osteoclasts
Biochemical and Biophysical Research Communications, 2010Osteoclasts are multinucleated cells specialized in degrading bone and characterized by high expression of the enzymes tartrate-resistant acid phosphatase (TRAP) and cathepsin K (CtsK). Recent studies show that osteoclasts exhibit phenotypic differences depending on their anatomical site of action.
Serhan, Zenger +2 more
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Multinuclearity of Osteoclasts
Nature, 1963THE origin and function of the multinuclear osteoclast cell are of continuing interest among contemporary investigators, and have a long history among investigations on amphibian regeneration1,2.
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The osteoclast and periodontitis
Journal of Clinical Periodontology, 1986Abstract. The osteoclast may play an important rô le in the variable rate of osseous destruction seen in periodontitis. Current understanding of various aspects of the osteoclast may help explain this fact. This review paper will first look at two theories of cell origin of the osteoclast: the multipotential osteoprogenitor cell theory and the ...
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Microscopy Research and Technique, 2003
AbstractOsteoclasts are the only cells capable of resorbing mineralised bone, dentine and cartilage. Osteoclasts act in close concert with bone forming osteoblasts to model the skeleton during embryogenesis and to remodel it during later life. A number of inherited human conditions are known that are primarily caused by a defect in osteoclasts. Most of
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AbstractOsteoclasts are the only cells capable of resorbing mineralised bone, dentine and cartilage. Osteoclasts act in close concert with bone forming osteoblasts to model the skeleton during embryogenesis and to remodel it during later life. A number of inherited human conditions are known that are primarily caused by a defect in osteoclasts. Most of
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Journal of Cellular Biochemistry, 1994
AbstractIn biological research, new ideas arise and quickly spread to encompass the entire field. Thus, the evolution of molecular biology has significantly changed our methods of approaching our research. A similar far‐reaching finding has been the advent of radical reactions into biology.
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AbstractIn biological research, new ideas arise and quickly spread to encompass the entire field. Thus, the evolution of molecular biology has significantly changed our methods of approaching our research. A similar far‐reaching finding has been the advent of radical reactions into biology.
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Generation of Osteoclasts In Vitro, and Assay of Osteoclast Activity
2007Osteoclasts are bone-resorbing multinucleated cells derived from the monocyte-macrophage lineage. The authors have developed a mouse marrow culture system and a coculture system of mouse osteoblasts and hemopoietic cells, in which osteoclasts are formed in response to various osteotropic factors such as 1alpha,25-dihydroxyvitamin D3, parathyroid ...
Naoyuki, Takahashi +3 more
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Annals of the New York Academy of Sciences, 2006
Abstract: The osteoclast is the unique bone resorptive cell that accomplishes its mission by forming an isolated acidified microenvironment between itself and the bone surface. Creation of this compartment is the first step in bone degradation and establishes that an intimate physical relationship must exist between the osteoclast and bone.
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Abstract: The osteoclast is the unique bone resorptive cell that accomplishes its mission by forming an isolated acidified microenvironment between itself and the bone surface. Creation of this compartment is the first step in bone degradation and establishes that an intimate physical relationship must exist between the osteoclast and bone.
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