Results 161 to 170 of about 87,738 (302)

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar   +11 more
wiley   +1 more source

Mineral‐targeted alkaline phosphatase improves bone graft‐mediated alveolar bone defect healing in mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Alveolar bone loss challenges tooth retention and implant placement. Freeze‐dried bone allograft (FDBA) is widely used for alveolar ridge preservation but has limitations in resorption rate and healing time. In this proof‐of‐concept study, we tested whether pro‐mineralization enzyme, tissue‐nonspecific alkaline phosphatase (TNAP ...
Kedith Sawangsri   +4 more
wiley   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis   +11 more
wiley   +1 more source

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro   +7 more
wiley   +1 more source

ASXL1 impairs osteoclast formation by epigenetic regulation of NFATc1 [PDF]

open access: yes, 2018
Abu-Amer, Yousef   +6 more
core   +1 more source

Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis [PDF]

open access: yes, 2018
Bukowska-Straková, Karolina   +8 more
core   +1 more source

Estradiol replacement attenuates alendronate‐associated adverse effects on alveolar bone repair in ovariectomized rats

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Sodium alendronate (ALN) is widely used to treat postmenopausal osteoporosis, but both estrogen deficiency and antiresorptive therapy may impair alveolar bone repair after tooth extraction. A clinically relevant but insufficiently explored scenario involves estrogen‐deficient individuals receiving hormone replacement therapy (HRT ...
Pedro H. C. Isaias   +9 more
wiley   +1 more source

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