Genetic Susceptibility to Periodontitis
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
Correction: Salviaflaside in water-soluble fraction of heated water extracted from defatted <i>Perilla frutescens</i> Britton var. <i>japonica</i> Hara seed residue suppresses osteoclast differentiation. [PDF]
Asano H, Nishimoto S.
europepmc +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source
Transcription factor GTF2I regulates osteoclast differentiation through mediating miR-134-5p and MAT2A expressions. [PDF]
Tang L +5 more
europepmc +1 more source
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation. [PDF]
Xu W, Lv S, Wang X, Song C, Xi C, Yan J.
europepmc +1 more source
The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Cell cycle checkpoint factor p15<sup>Ink4b</sup> is a novel regulator of osteoclast differentiation. [PDF]
Tsuji S +11 more
europepmc +1 more source
Biomaterial Cues for Regulation of Osteoclast Differentiation and Function in Bone Regeneration. [PDF]
Shariati K +9 more
europepmc +1 more source

