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Osteoclast: Origin and Differentiation
2005hydroxyapatite surface has led to a fuller understanding of this important cell. In this introductory chapter we set out the basic aspects of osteoclast origin and differentiation. Beginning with a description of the multinuclear cell found in bone and a brief introduction to its typing through functional characteristics, we discuss developing research
Janet Rubin, Edward M. Greenfield
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Macrophage Polarization and Osteoclast Differentiation
Macrophages are a key player to regulate rheumatoid arthritis pathogenesis from onset to remission. They can alter innate functions under microenvironmental conditions. To understand heterogeneous functions of macrophages in rheumatoid arthritis, several activated statuses of macrophages should be mimicked in vitro.Noritaka, Saeki, Akihiro, Nakata
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Osteoblast and Osteoclast Differentiation in Modeled Microgravity
Annals of the New York Academy of Sciences, 2007Abstract: Prolonged microgravity experienced by astronauts is associated with a decrease in bone mineral density. To investigate the effect of microgravity on differentiation of osteoclasts and osteoblasts, we used a NASA‐recommended, ground‐based, microgravity‐simulating system, the Rotary Cell Culture System (RCCS).
Ritu, Saxena +2 more
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[Differentiation of osteoclasts].
Clinical calcium, 2005The differentiation and functions of osteoclasts (OCs) are regulated by osteoblast-derived factors such as receptor activator of NF kappa; B ligand (RANKL) that stimulates OC formation and a novel secreted member of the TNF receptor superfamily, osteoprotegerin (OPG), that negatively regulates osteoclastogenesis.
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[Osteoclast differentiation and activation].
Clinical calcium, 2007In autoimmune arthritis, activation of T cells induces bone destruction through receptor activator of NF-kappaB ligand (RANKL) . Recent study revealed interleukin-17 (IL-17) -producing helper T cell subset (Th17) , but not IFN-gamma-producing Th1, to be responsible for bone destruction.
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Osteoclast differentiation and activity
Biochemical Society Transactions, 1998openaire +2 more sources
The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function
Biomolecules, 2020Antonio Filippini +2 more
exaly

