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Osteoclast: Origin and Differentiation

2005
hydroxyapatite surface has led to a fuller understanding of this important cell. In this introductory chapter we set out the basic aspects of osteoclast origin and differentiation. Beginning with a description of the multinuclear cell found in bone and a brief introduction to its typing through functional characteristics, we discuss developing research
Janet Rubin, Edward M. Greenfield
openaire   +1 more source

Macrophage Polarization and Osteoclast Differentiation

Macrophages are a key player to regulate rheumatoid arthritis pathogenesis from onset to remission. They can alter innate functions under microenvironmental conditions. To understand heterogeneous functions of macrophages in rheumatoid arthritis, several activated statuses of macrophages should be mimicked in vitro.
Noritaka, Saeki, Akihiro, Nakata
openaire   +2 more sources

Osteoblast and Osteoclast Differentiation in Modeled Microgravity

Annals of the New York Academy of Sciences, 2007
Abstract:  Prolonged microgravity experienced by astronauts is associated with a decrease in bone mineral density. To investigate the effect of microgravity on differentiation of osteoclasts and osteoblasts, we used a NASA‐recommended, ground‐based, microgravity‐simulating system, the Rotary Cell Culture System (RCCS).
Ritu, Saxena   +2 more
openaire   +2 more sources

[Differentiation of osteoclasts].

Clinical calcium, 2005
The differentiation and functions of osteoclasts (OCs) are regulated by osteoblast-derived factors such as receptor activator of NF kappa; B ligand (RANKL) that stimulates OC formation and a novel secreted member of the TNF receptor superfamily, osteoprotegerin (OPG), that negatively regulates osteoclastogenesis.
openaire   +1 more source

[Osteoclast differentiation and activation].

Clinical calcium, 2007
In autoimmune arthritis, activation of T cells induces bone destruction through receptor activator of NF-kappaB ligand (RANKL) . Recent study revealed interleukin-17 (IL-17) -producing helper T cell subset (Th17) , but not IFN-gamma-producing Th1, to be responsible for bone destruction.
openaire   +1 more source

Protocadherin-7 Regulates Osteoclast Differentiation through Intracellular SET-Binding Domain-Mediated RhoA and Rac1 Activation

International Journal of Molecular Sciences, 2021
Yongwon Choi   +2 more
exaly  

Osteoclast Differentiation

2004
Sakamuri V. Reddy, G. David Roodman
openaire   +1 more source

The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function

Biomolecules, 2020
Antonio Filippini   +2 more
exaly  

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