Results 211 to 220 of about 919,707 (247)

Correction to "Systematical Mutational Analysis of FRATtide against Osteoclast Differentiation by Alanine Scanning". [PDF]

ACS Med Chem Lett
Yang Y, Geng C, Shen H, Chao J, Wang Z, Cong W, Li X, Ye G, Jiang Y.   +8 more
europepmc   +1 more source

High‐Fat Diet Reprograms the Periapical Immune Landscape in a Mouse Model of Apical Periodontitis: A Spatial Transcriptomics Study

International Endodontic Journal, EarlyView.
ABSTRACT Introduction Apical periodontitis (AP) is an inflammatory disease of the periapical tissues driven by host responses to endodontic infection, and systemic metabolic disturbances, such as high‐fat diet (HFD)–induced dysmetabolism, may exacerbate tissue destruction. This study aimed to determine how chronic HFD exposure alters periapical myeloid
Maryam Ghaffari, Aiman Ali, Clement Hartadi, Annie Shrestha   +3 more
wiley   +1 more source

CD68 and F4/80 Markers Demonstrate Inflammatory Synergism Between Apical Periodontitis and Liver Fibrosis in Wistar Rats

International Endodontic Journal, EarlyView.
ABSTRACT Aim To evaluate CD68 and F4/80 glycoproteins in the worsening of apical periodontitis (AP) and liver fibrosis (LF) in Wistar rats. Methodology Thirty‐two Wistar rats were distributed in the following groups (n = 8): C—control; AP—apical periodontitis; LF—liver fibrosis; APLF—AP and LF.
L. V. Barroti, C. Cantiga‐Silva, M. P. Justo, P. H. C. Oliveira, F. D. Faria, J. Goto, E. Ervolino, G. Sivieri‐Araújo, T. N. Pinheiro, L. T. A. Cintra   +9 more
wiley   +1 more source

Impact of substrate choice on human osteoclast differentiation and secretome: Implications for targeted therapeutic development. [PDF]

PLoS One
D'Amélio F, Vigerelli H, Araldi RP, da Costa Neves A, Prieto-da-Silva ÁRB, Pimenta D, Kerkis I.   +6 more
europepmc   +1 more source

Chronic Excessive Exercise Aggravates Apical Periodontitis in Mice

International Endodontic Journal, EarlyView.
ABSTRACT Aim To investigate the effects of overtraining on the development of apical periodontitis (AP) in mice. Methodology Sixty 6‐week‐old male C57BL/6 mice were allocated to six groups: sedentary without AP (SED); sedentary with AP (SED AP); aerobic training without AP (AERO); aerobic training with AP (AERO AP); overtraining without AP (OVER); and ...
Andréia Bosco Boaventura, Rosmeli Daysi Coasaca‐Rivera, Bárbara Roma Mendes, Sandra Lia do Amaral, Adelino Sanchez Ramos da Silva, Paulo Sergio Cerri, Gisele Faria   +6 more
wiley   +1 more source

ANXA2 Regulates RANKL-Induced Osteoclast Differentiation Through STAT3 Signaling in Breast Cancer. [PDF]

Breast Cancer (Dove Med Press)
Yuan J, Xin F, Wang R.
europepmc   +1 more source

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

Immunology, EarlyView.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang, Fengyu Liu, Yongle Wei, Guoqiang Li, Liujie Zheng, Lin Jin, Feng Luan, Yingze Zhang, Ling Wang, Zhiyong Hou   +9 more
wiley   +1 more source

<i>Brucella melitensis</i> clinical isolate modulates osteoclast differentiation to drive pathological bone destruction in brucellar arthritis. [PDF]

Front Cell Infect Microbiol
Chen J, Zhi F, Zhao G, Su M, Tuo J, Song W, Chu Y, Zhang H.   +7 more
europepmc   +1 more source