Results 211 to 220 of about 87,738 (302)

MSDC-0160, a novel clinical-stage mitochondrial pyruvate carrier inhibitor, suppresses osteoclast differentiation and alleviates type 2 diabetes-related bone loss. [PDF]

J Transl Med
Wang C, Hai N, Chen L, Huang Q, Gui Y, Su Y, Lian H, Liang J, Zhao J, Xu J, Liu Q.   +10 more
europepmc   +1 more source

Withdrawn: Impact of the RNF123 mutation on osteoclast differentiation in familial ankylosing spondylitis

Rheumatology &Autoimmunity, EarlyView.
Jin S, Ji X, Zhang L, Shi Y, Zhao D, Wan W. Impact of the RNF123 mutation on osteoclast differentiation in familial ankylosing spondylitis. Rheumatol & Autoimmun. 2023;1‐8. doi:10.1002/rai2.12102 Withdrawal: The above article, first published online 11th September 2024, on Wiley Online Library (wileyonlinelibrary.com), has been withdrawn by agreement ...
wiley   +1 more source

Effect of aging on healing of mandibular tooth extraction socket in a rat model

European Journal of Oral Sciences, EarlyView.
Abstract This study evaluated the effect of aging on bone regeneration in mandibular extraction sockets. Male Sprague–Dawley rats were divided into three age groups: 2‐month‐old (2 M, n = 6), 10‐month‐old (10 M, n = 6), and 18‐month‐old (18 M, n = 5). Two weeks post‐extraction, comprehensive analyses were performed using micro‐computed tomography (µ‐CT)
Kyung Su Shin, Han Wool Kwak, Jong‐Seong Chae, Si‐On Choi, Suah Han, Hwa Young Yu, Dae Ho Leem, Hyun Seok   +7 more
wiley   +1 more source

Slit2 inhibits SRC-PI3K signaling pathway, regulates osteoclast differentiation of macrophages and reduces bone resorption. [PDF]

Front Cell Dev Biol
Ge Q, Zou Y, Deng H, Yang Z, Ge L, Huang J, Cai J, Wang L.   +7 more
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

KIAA1429-mediated M⁶A methylation inhibits osteoclast differentiation via stabilizing Lrp4 mRNA and protects against osteoporosis. [PDF]

Cell Mol Biol Lett
Liu J, Fu Q, Li M, Chen J, Xu M, Zhai X, Li S, Li L, Wu X, Xu W, Wang K, Si H.   +11 more
europepmc   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment

The FEBS Journal, EarlyView.
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley   +1 more source

The role of purinergic signalling in the musculoskeletal system [PDF]

Abbracchio, Agrawal, Alvarenga, Armstrong, Banachewicz, Berenbaum, Biswas, Biver, Bonewald, Bowler, Bowler, Bowler, Brandao-Burch, Brown, Buckley, Buckley, Buckley, Bulman, Burnstock, Burnstock, Burnstock, Burnstock, Buscher, Buvinic, Campo, Carroll, Caswell, Caswell, Chenu, Cheung, Choi, Chowdhury, Costa, Costessi, Croucher, Deli, Dixon, Evans, Ferrari, Fleisch, Fleisch, Fodor, Gartland, Gartland, Gartland, Gartland, Gartland, Genetos, Genetos, Gharibi, Gharibi, Graff, Graff, Grol, Hajjawi, Hayton, Hazama, He, Hecht, Hessle, Hiken, Hoebertz, Hoebertz, Hoebertz, Hollopeter, Hsu, Hung, Huo, Husted, Ihara, Isabel R. Orriss, Jande, Janssens, Janssens, Johnson, Jones, Jorgensen, Jorgensen, Jorgensen, Kanabe, Kaplan, Kaplan, Kara, Kara, Katz, Katz, Ke, Keresztes, Knight, Kono, Koolpe, Koolpe, Korcok, Korcok, Kringelbach, Kudirka, Kumagai, Kumagai, Lee, Leong, Leong, Lerner, Lerner, Li, Li, Liu, Mackenzie, Martinello, Masin, Mediero, Mediero, Meyer, Millward-Sadler, Morrison, Mortensen, Naemsch, Naemsch, Nakamura, Nicke, Nishii, Noronha-Matos, Noronha-Matos, Ohlendorff, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Panupinthu, Panupinthu, Pellegatti, Penolazzi, Pines, Ralevic, Reimer, Riddle, Romanello, Romanello, Rosenthal, Rumney, Ryan, Ryten, Schoenberg, Sciancalepore, Shimegi, Sistare, Su, Suzuki, Syberg, Syberg, Takedachi, Tesch, Thompson, Tu, Varani, Varani, Vincenzi, Voss, Wang, Wang, Wang, Weidema, Weidema, Wesselius, Wesselius, Wesselius, Wiebe, Wildman, You, Yu, Yu, Zimmermann, Zippel   +176 more
core   +1 more source