Results 111 to 120 of about 31,404 (249)

An Exploratory Longitudinal Analysis of Salivary Host, Bacterial and Fungal Extracellular Vesicles Following 6‐Month Non‐Surgical Periodontal Therapy in Periodontitis

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the longitudinal changes in salivary host and non‐host extracellular vesicles (EVs) following non‐surgical periodontal therapy (NSPT). Materials and Methods Unstimulated saliva and plaque (from a deep pocket) were collected from 25 Stage III/IV periodontitis patients at baseline and at 3 and 6 months post NSPT.
Chun Liu, Jenny Wang, Andrew Lai, Carlos Salomon, Chaminda Jayampath Seneviratne, Sašo Ivanovski, Pingping Han   +6 more
wiley   +1 more source

Eccentric Occlusal Loads Remodel the Dentoalveolar and Temporomandibular Biomechanical Unit in Rats

Journal of Oral Rehabilitation, EarlyView.
Eccentric occlusal loads remodel the dentoalveolar and temporomandibular joints in the masticatory biomechanical unit in rats. (A) Bite block as an occlusal rise (OR) on the rat maxillary first molar (green region) is shown. (B) 18F‐NaF Positron emission tomography localised regions of higher metabolic activity (higher uptake in the left condyle ...
Haochen Ci, Umama Ali, Zhiyuan Yang, Ayush Bakhandi, Nhu Huynh, Christine Nguyen, Brandon Lee, Youngho Seo, Robert Flavell, Alireza Hatamifar, Rishi J. Gupta, Rebeka Silva, Yongmei Wang, Bo Wang, Sunita P. Ho   +14 more
wiley   +1 more source

Implant stability quotient and osteogenic process in dental implant sites prepared using piezoelectric technique: A study in minipigs

Journal of Prosthodontics, EarlyView.
Abstract Purpose Few studies have explored the bone response in dental implant sites prepared using a piezoelectric device, indicating moderate effectiveness in enhancing secondary stability and osteogenesis. This study seeks to expand our understanding of the changes in biological, clinical, and radiographic parameters, during the initial phases of ...
Gianmario Schierano, Domenico Baldi, Bruno Peirone, Mitzy Mauthe von Degerfeld, Fabio Modica, Vincenzo Notaro, Cecilia Boretto, Giuliana Muzio, Riccardo Autelli   +8 more
wiley   +1 more source

The effect of the IL-6 monoclonal blocker on the course of aseptic femoral head necrosis in the experiment (pilot study)

Гений oртопедии
Background There is currently no pathogenetically based treatment for aseptic necrosis of the femoral head. One of the most promising areas of possible targeted therapy is the use of genetically engineered drugs, including monoclonal blockers of ...
Nikita A. Shabaldin, Anna V. Sinitskaya, Lyudmila N. Igisheva, Lev A. Bogdanov, Andrey V. Shabaldin   +4 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Bone Grafts: Everything You Need to Know

Journal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen, Javier Sanz, Giuseppe Perale, Augustine Mark Saiz, Mario Romandini, Maryam Rahmati   +5 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source