Results 121 to 130 of about 29,684 (190)
ABSTRACT This study presents a novel approach to enhance the early‐stage osseointegration of orthopedic implants through surface engineering. Lithium (Li), strontium (Sr), and silver (Ag)‐doped hydroxyapatite (HA) were coated on Ti6Al4V substrates using RF induction based plasma spray coating and loaded with polydopamine (PD) and Cissus quadrangularis ...
Susmita Bose +5 more
wiley +1 more source
LincRNA-EPS alleviates osteoclastogenesis under inflammatory microenvironment through preventing excessive iron metabolism. [PDF]
Wang J, Wang Y, Zhang Z, Wang X, Su J.
europepmc +1 more source
ABSTRACT Background Skeletal muscle atrophy is a frequent comorbidity of metabolic disorders and chronic diseases, and despite its high prevalence, no pharmacological therapy is available, representing a major unmet clinical need. Adiponectin and its receptors are key regulators of skeletal muscle metabolism, mitochondrial function and myogenesis, yet ...
Md. Rameez Moin +12 more
wiley +1 more source
The dinitrothiophenol SN-2 reduces osteoclastogenesis and estrogen deficiency-induced bone loss by inhibiting TRAF6 auto-ubiquitination. [PDF]
Lu J +10 more
europepmc +1 more source
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley +1 more source
Role of Caffeine and Ethanol in Modulating Expression of Receptor Activator of Nuclear Factor κβ (RANK) and Osteoprotegerin (OPG) during Orthodontic Tooth Movement: An In Vivo Study. [PDF]
Pawinru AS +8 more
europepmc +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric ...
Bing Tan +6 more
wiley +1 more source
TTC26 scaffolds MINDY3-mediated RACK1 deubiquitination to drive osteoclastogenesis and pathological bone resorption. [PDF]
Gao Y +9 more
europepmc +1 more source
ABSTRACT Transepithelial calcium absorption occurs via a transcellular or paracellular pathway. The intestinal transcellular pathway relies, at least partially, on the apical calcium channel transient receptor potential vanilloid 6 (TRPV6), whereas paracellular calcium (re)absorption occurs through tight junction proteins, including claudin‐2 (CLDN2 ...
Harneet Kaur Bhullar +6 more
wiley +1 more source

