Runt-related transcription factor 2 transcriptionally represses sirtuin 1 to regulate osteoclastogenesis and tooth eruption. [PDF]
Li J +6 more
europepmc +1 more source
The role of acquired host immunity in periodontal diseases
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane +2 more
wiley +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
C-type lectin receptors: bone remodeling and therapeutic potential. [PDF]
Kleim M, Bozec A, Weber M, Groetsch B.
europepmc +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Gut microbiota-immune-bone axis in osteoporosis: mechanisms and intervention strategies. [PDF]
Huang M, Xie B, Liu H.
europepmc +1 more source
Relationship between vitamin D deficiency and early implant failure and osseointegration
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron +8 more
wiley +1 more source
Microbial-Derived Daidzin (Eco-3) Suppresses RANKL-Induced Osteoclastogenesis by Targeting the TBK1-NFATc1 Signaling Axis. [PDF]
Perumal NL, Koo KB, Park GY, Jang BC.
europepmc +1 more source
Emerging risk factors influencing the occurrence of peri‐implantitis
Abstract Background The objective of the present review is to explore the evidence and biological plausibility of factors that may expose dental implants to a greater likelihood of developing peri‐implantitis. Material and Methods An electronic screening on the PubMed library the was carried out to identify potential emerging factors that influence the
Alberto Monje +3 more
wiley +1 more source
WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M<sup>6</sup>A-Mediated Regulation of CSF1R Signaling in Estrogen-Deficient Osteoporosis. [PDF]
Shen C +14 more
europepmc +1 more source

