Metabolic reprogramming of the immune response in periodontitis
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon +3 more
wiley +1 more source
Isoschaftoside Inhibits Osteoclastogenesis by Suppressing the NF-κB and MAPK Pathways. [PDF]
Yun J, Lee KY, Park B.
europepmc +1 more source
Decoding host–microbial dynamics in peri‐implantitis: Ecosystem‐specific experimental models
Abstract Background Peri‐implantitis is an inflammatory disease arising within a unique host–microbial–biomaterial ecosystem. Unlike periodontitis, peri‐implant tissues lack a periodontal ligament and epithelial junction integrity and interface with metal oxides on titanium surfaces.
Georgios A. Kotsakis +5 more
wiley +1 more source
Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells. [PDF]
Lin CY +4 more
europepmc +1 more source
Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach +5 more
wiley +1 more source
Reprogramming bone homeostasis: The recoupling-oriented framework of bidirectional regulation strategies for osteoporosis. [PDF]
Niu J +8 more
europepmc +1 more source
Abstract Background/Aim Antiresorptive therapy represents a cornerstone in the management of osteoporosis and cancer‐related bone disease through suppression of osteoclast‐mediated bone resorption. As implant therapy becomes more common in aging populations, clinicians increasingly encounter patients receiving these medications, thus making their ...
Emilio A. Cafferata +2 more
wiley +1 more source
Corrigendum to "Human umbilical cord mesenchymal stem cells secretome and nanoemulsion propolis combination ameliorate osteoclastogenesis in lipopolysaccharide-induced osteolysis in hyperglycemia rats" [J Dent Sci] 20 (2025) 2181-2188. [PDF]
Nugraha AP +14 more
europepmc +1 more source
The osteoimmune cell atlas of peri‐implantitis: A narrative scoping review
Abstract Background/Aim Peri‐implantitis represents a complex osteoimmune disorder characterized by dysregulated cellular ecosystems that drive chronic inflammation and accelerated peri‐implant bone loss. Materials and Methods This article was designed as a narrative scoping review to map and integrate the available evidence from transcriptomics ...
Emilio A. Cafferata +2 more
wiley +1 more source
Correction: Site-1 protease controls osteoclastogenesis by mediating LC3 transcription. [PDF]
Zheng Z +11 more
europepmc +1 more source

