Results 161 to 170 of about 31,404 (249)

Musculoskeletal decay and bone–muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures

Experimental Physiology, EarlyView.
Abstract Older adults experience a markedly increased risk of falls and fractures following hospital discharge, largely due to the rapid musculoskeletal deterioration associated with bed rest. Although age‐related muscle and bone loss typically develops gradually, acute physical inactivity accelerates key biological processes underlying sarcopenia and ...
Julia Margarita Reyes, Guy Hajj‐Boutros, Dounia Rouabhia, José Morais, Felipe Salech, Gustavo Duque   +5 more
wiley   +1 more source

RANKL-convergent osteoimmune network framework in osteoporosis: integrating macrophage activation, T-cell imbalance, and cytokine crosstalk. [PDF]

Front Immunol
Zheng K, Ouyang Y, Jiang W, Wang S, Lan B, Nik Ramli NN, Yin C.   +6 more
europepmc   +1 more source

Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025)

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang, Jinqin Wei, Zhao Jiang, Yingming Luo, Yan Zhou, Jiafan Yang, Hui Cui   +6 more
wiley   +1 more source

Melatonin Suppresses Osteoclastogenesis via Inhibiting Iron/ROS-CREB/PGC-1β-Mediated Mitochondrial Biogenesis. [PDF]

J Pineal Res
Yang J, Che J, Yang M, Feng Y, Li Q, Zeng Y.   +5 more
europepmc   +1 more source

Anti‐Inflammatory Yerba Mate‐Loaded Electrospun Polycaprolactone/Gelatin Membranes for the Management of Endodontic‐Periodontal Lesions

Journal of Biomedical Materials Research Part A, Volume 114, Issue 11, November 2026.
ABSTRACT Combined endodontic‐periodontal diseases require integrated endodontic and periodontal treatment. However, extensive bone loss can limit the use of conventional approaches, necessitating regenerative methods such as guided tissue regeneration to manage intrabony defects.
Caroline Anselmi, Sahar Aminmansour, Igor P. Mendes Soares, Sepideh Aminmansour, Lais M. Cardoso, Carolina Sayuri Wajima, Sarah Chang, Luciano T. A. Cintra, Renan Dal‐Fabbro, Marco C. Bottino   +9 more
wiley   +1 more source

Osteoclastogenesis inhibitor identified [PDF]

Nature Reviews Rheumatology, 2009
openaire   +1 more source

Hydrocalumite‐Like Material Induces Early Osteogenic Priming and ECM Remodeling Without Effective Mineralization in Preosteoblasts

Journal of Biomedical Materials Research Part A, Volume 114, Issue 11, November 2026.
ABSTRACT Hydrocalumite‐like phases, belonging to the layered double hydroxide family, are potential biomaterials for bone repair; however, their cellular effects remain incompletely understood. Here, we evaluated a hydrocalumite‐like material of composition [Ca2Al(OH)₆]Cl·nH2O (abbreviated Ca2Al–Cl) in preosteoblastic MC3T3‐E1 cells, assessing ...
C. J. da Costa Fernandes, G. S. de Almeida, M. Pires Figueiredo, V. R. L. Constantino, W. F. Zambuzzi   +4 more
wiley   +1 more source

Epigenetic regulatory networks in the pathogenesis and treatment of osteoporosis subtypes. [PDF]

Mol Biomed
Ren Z, Dai B, Chen D, Li Z, Meng K, Lan S, Liu C, Zhang Z, Mo X.   +8 more
europepmc   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

RUNX2 promotes osteoclast differentiation and bone resorption via the newly identified LncRNA-ROD: implications for alveolar remodeling. [PDF]

Int J Oral Sci
Li J, Liu Y, Qiao Y, Yan C, Zhao W, Ji L, Liu D, Xin Y, Zhang C, Wang X, Wang Y, Zheng S.   +11 more
europepmc   +1 more source