Results 171 to 180 of about 53,100 (272)

Expansion of bone marrow adipocytes in obese mice leads to PD-L1-driven bone marrow immunosuppression and osteoclastogenesis. [PDF]

Bone Res
Costa SN, Chlebek C, Gray L, Caradonna P, Ryzhov S, Rosen CJ.   +5 more
europepmc   +1 more source

Inflammatory osteolysis: A conspiracy against bone [PDF]

, 2017
Abu-Amer, Abu-Amer, Anton, Bardin, Beranger, Chen, Christo, Claro, Cobelli, Coll, Dapunt, Deborah V. Novack, Dewhirst, Gabriel Mbalaviele, Georg Schett, Gravallese, Harre, Josse, Jovanovic, Kollias, Lukens, Maitra, McCall, Mukai, Negishi-Koga, Osta, Ozen, Pasco, Robaszkiewicz, Rubbert-Roth, Sanchez, Scianaro, Sharma, Steven L. Teitelbaum, Van Hauwermeiren, Wang, Zaki   +36 more
core   +2 more sources

Lysosome biogenesis during osteoclastogenesis

, 2006
Lysosomes are acidic, hydrolase-rich vesicles capable of degrading most biological macromolecules. During the past several decades, much has been learned about different aspects of lysosome biogenesis. The selective phosphorylation of mannose residues on lysosomal enzymes, in conjunction with specific receptors for the mannose-6-phosphate recognition ...
openaire   +1 more source

Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G., Kamini Shivhare, Piyush Kumar Gupta, Amirhossein Sahebkar, Prashant Kesharwani, Rahul Shukla   +5 more
wiley   +1 more source

Correction: Periplogenin attenuates LPS-mediated inflammatory osteolysis through the suppression of osteoclastogenesis via reducing the NF-κB and MAPK signaling pathways. [PDF]

Cell Death Discov
Gan K, Lian H, Yang T, Huang J, Chen J, Su Y, Zhao J, Xu J, Liu Q.   +8 more
europepmc   +1 more source

Intra‐Tissue Bacteriome and Cellular Profiles in Periodontal Granulation Tissue From Osseous Defects and Extraction Sockets

Journal of Clinical Periodontology, Volume 53, Issue 5, Page 806-820, May 2026.
ABSTRACT Aim To investigate the intra‐tissue bacteriome and cell profiles within periodontal granulation tissue (PGT) for exploring the biological essence and translational potentials. Materials and Methods PGT samples were collected from 49 patients with severe periodontitis—including those from osseous defects (GT) during periodontal surgery ...
Tianfan Cheng, Tianle Li, Tsz Yung Wong, Beibei Chen, Chongshan Liao, Xun Ding, Hui Chen, Wei Qiao, George Pelekos, Lijian Jin   +9 more
wiley   +1 more source

Immune Checkpoint Inhibitors and Bone Health: Mechanisms, Clinical Implications, and Emerging Perspectives on Bone Fragility. [PDF]

Curr Osteoporos Rep
Bedir ME, Uguz AC, Beypinar I, Unal M.
europepmc   +1 more source

Serum CTRP3 and CysC correlate with glucose, lipid, and bone metabolism in elderly patients with type 2 diabetes mellitus complicated with osteoporosis

Journal of Diabetes Investigation, Volume 17, Issue 5, Page 880-891, May 2026.
Serum levels of CTRP3 and CysC in elderly patients with T2DM and OP are closely associated with glucose‐lipid metabolism, bone mineral density, and bone metabolism markers. Combined detection of these two markers can assist in distinguishing OP in elderly patients with T2DM.
Yi‐Peng Wang, Yong Wang, Tao Chen, Gang Chen, Ze‐Yu Yang   +4 more
wiley   +1 more source

TSP-1 interaction with RANK and OPG: implications for bone remodeling and osteolytic bone metastasis. [PDF]

Cell Death Dis
Carminati L, Sangalli F, Urbinati C, Longhi E, Tomasoni G, Borsotti P, Midwood KS, Carlessi E, Rusnati M, Taraboletti G.   +9 more
europepmc   +1 more source

3D morphological analysis of age and sex‐related changes in human cortical bone remodeling spaces using micro‐CT

Journal of Anatomy, Volume 248, Issue 5, Page 719-738, May 2026.
This study investigates human cortical bone remodeling space morphology and its relationship with age and sex using micro‐CT imaging. Remodeling space morphology exhibits great inter‐ and intraindividual variation. Its dimensions decrease with increasing age, but do not differ between sexes.
Xuan Wei, Lindsay L. Loundagin, David M. L. Cooper   +2 more
wiley   +1 more source