Results 131 to 140 of about 132,120 (348)

Supplementary Figures 1-5 from Osteoclast-Derived Matrix Metalloproteinase-7, but Not Matrix Metalloproteinase-9, Contributes to Tumor-Induced Osteolysis

, 2023
Sophie Thiolloy, Jennifer L. Halpern, Ginger E. Holt, Herbert S. Schwartz, Gregory R. Mundy, Lynn M. Matrisian, Conor C. Lynch   +6 more
openalex   +2 more sources

The Role of Extracellular Vesicles MicroRNAs in Sarcopenia: From Aging to Multi‐Morbidity

AGING MEDICINE, EarlyView.
Exosomes transporting miRNAs play a crucial bidirectional regulatory role in the process of sarcopenia, both in natural aging and under various pathological conditions. ABSTRACT Sarcopenia, defined as progressive loss of skeletal muscle mass and function, occurs during aging and has also been recognized for its detrimental effects in various disease ...
Bingyu Huang, Zhao Peng, Lin Kang
wiley   +1 more source

Supplementary Figure Legend from Myeloid-Derived Suppressor Cells Function as Novel Osteoclast Progenitors Enhancing Bone Loss in Breast Cancer

, 2023
Anandi Sawant, Jessy S. Deshane, Joel Jules, Carnella M. Lee, Brittney A. Harris, Feng Xu, Selvarangan Ponnazhagan   +6 more
openalex   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Supplemental Table 1 from Bortezomib Inhibits Giant Cell Tumor of Bone through Induction of Cell Apoptosis and Inhibition of Osteoclast Recruitment, Giant Cell Formation, and Bone Resorption

, 2023
Leqin Xu, Jianbin Luo, Rongrong Jin, Zhiying Yue, Peng Sun, Zhengfeng Yang, Xinghai Yang, Wei Wan, Jishen Zhang, Shichang Li, Mingyao Liu, Jianru Xiao   +11 more
openalex   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Histological evaluation of the effects of corticotomy on induced orthodontic movement in rats

Revista de Odontologia da UNESP
: Introduction: Alveolar corticotomy is a surgical procedure used to increase the velocity of tooth movement. Objective Identify histological evidence of the effect of corticotomy on orthodontic movement in rats.
Patrícia Pigato SCHNEIDER, Lais Pavan SILVA, Fernando José Lopes de Campos CARVALHO, Luís Filipe Siu LON, Luiz Gonzaga GANDINI JÚNIOR   +4 more
doaj   +1 more source

CCL25 and CCR9 is a unique pathway that potentiates pannus formation by remodeling RA macrophages into mature osteoclasts [PDF]

, 2020
Sadiq Umar, Karol Palasiewicz, Katrien Van Raemdonck, Michael V. Volin, Bianca Romay, Imran Ahmad, Chandana Tetali, Nadera Sweiss, M. Asif Amin, Ryan K. Zomorrodi, Shiva Shahrara   +10 more
openalex   +1 more source

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

Animal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng, Zhe Zhao, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Zhengyang Lin, Zhenhan Deng, Wencui Li   +8 more
wiley   +1 more source

Inflammation and osteoclasts

Japanese Journal of Clinical Immunology, 2017
  Osteoclasts are differentiated from precursors of the monocyte/macrophage lineage originated from bone marrow hematopoietic stem cells and are the sole bone-resorbing cells in the body. Osteoclast differentiation is thought to require M-CSF (macrophage colony-stimulating factor) and RANKL (receptor activator of nuclear factor kappa-B ligand ...
openaire   +3 more sources