Results 111 to 120 of about 81,648 (311)

Giant cells around bone biomaterials: Osteoclasts or multi-nucleated giant cells?

, 2016
Recently accumulating evidence has put into question the role of large multinucleated giant cells (MNGCs) around bone biomaterials. While cells derived from the monocyte/macrophage lineage are one of the first cell types in contact with implanted ...
Hamoon Zohdi, Masako Fujioka-Kobayashi, Zohdi, Hamoon, Miron, Richard John, Richard J. Miron, Kobayashi, Masako, Bosshardt, Dieter, Dieter D. Bosshardt   +7 more
core   +1 more source

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

The Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore, Madeline Tourigny, Diana Quinonez, Kevin Barr, Matthew W. Grol, Katherine E. Willmore   +5 more
wiley   +1 more source

Giant osteoclasts in patients under bisphosphonates

, 2014
International audienceBackground: Bisphosphonates have been widely used for treatment of high bone resorption states. It lowers bone turnover by inhibiting osteoclasts bone resorption with various mechanisms of actions: inhibition of osteoclast formation
Mac-Way, Fabrice, Lafage-Proust, Marie-Hélène, Fabrice Mac-Way, Andrea Trombetti, Trombetti, Andrea, Christian Noel, Marie-Hélène Lafage-Proust, Noel, Christian   +7 more
core   +1 more source

Differences in predominant collagen fiber orientation between dorsal and plantar trabecular bone tracts of adult mule deer calcanei suggest strain‐mode‐specific adaptation

The Anatomical Record, EarlyView.
Polarized microscopic images of the outer bone cortex (a and b) and deeper trabecular bone (c and d) of the deer calcaneus in thin cross‐sections. The brighter gray levels reflect more oblique‐to‐transverse collagen fibers in the compression/dorsal bone (a, c) and the darker gray levels reflect more longitudinal collagen in the tension/plantar bone (b,
John G. Skedros, John T. Cronin, Chad S. Mears, Brett W. Richards   +3 more
wiley   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

The immunophenotype of osteoclasts and macrophage polykaryons

, 2011
AIM: Osteoclasts are multinucleated cells which are specialised to carry out lacunar bone resorption. Osteoclasts form part of the mononuclear phagocyte system, and immunophenotypic criteria for distinction from macrophage polykaryons include expression ...
Forsyth, R., F. Maggiani, Krenacs , T, Krenacs, T., Hogendoorn , PA, R. Forsyth, N. A. Athanasou, Athanasou, Nicholas, Forsyth , R, Hogendoorn, PCW, Krenacs, T, Hogendoorn, PC, T. Krenacs, Athanasou , Nick, Athanasou, NA, Athanasou, N.A., Maggiani, Francesca, Hogendoorn, P.C.W., Maggiani, F., P. C. W. Hogendoorn, Maggiani, F, Forsyth, R   +21 more
core   +1 more source

The role of osteoclasts in breast cancer bone metastasis [PDF]

, 2016
Breast cancer frequently metastasises to the skeleton, interfering with the normal bone remodelling process and inducing bone degradation. Bone degradation is caused by osteoclasts, the normal bone-resorbing cells.
Le Pape, F., Vargas, Geoffrey, Clézardin, Philippe, Geoffrey Vargas, Clézardin, P., François Le Pape, Vargas, G., Philippe Clézardin, Le Pape, François   +8 more
core   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Osteoclasts And Their Extracellular Vesicles In Craniofacial Bone Regeneration

International Dental Journal
Aim or purpose: Bone remodeling is a tightly coupled process between bone-forming osteoblasts (OBs) and bone-resorbing osteoclasts (OCs) to maintain Craniofacial bone. However, the mechanisms responsible for the coupling between OCs and OBs have not been
Yang Zhang, Abdullah Faqueer, Taozhao Yu
doaj   +1 more source

Vesicular Trafficking in Osteoclasts [PDF]

, 2014
Osteoclasts are multinucleated bone-degrading cells that undergo large changes in their polarisation and vesicular trafficking during the bone resorption cycle.
Hirvonen, Mirkka
core