Results 21 to 30 of about 109,289 (351)
Scientific Reports, 2021 Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma.
Quitterie C. Larrouture +5 more
doaj +1 more source
Effects of a mesoporous bioactive glass on osteoblasts, osteoclasts and macrophages [PDF]
J. Colloid Interface Sci. 528, 309-320 (2018), 2021 A mesoporous bioactive glass (MBG) of molar composition 75SiO2-20CaO-5P2O5 (MBG-75S) has been synthetized as a potential bioceramic for bone regeneration purposes. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), nitrogen adsorption studies and transmission electron microscopy (TEM) demonstrated that MBG-75Spossess a highly ...
arxiv +1 more source
Osteoclasts and Arthritis [PDF]
Journal of Bone and Mineral Research, 2009 INFLAMMATORY ARTHRITIS TYPICALLY presents as joint pain, swelling, and stiffness, which may be of short duration. For example, parvovirus B 19 infection, attended by painful polyarticular swelling, generally resolves spontaneously within 2 wk without joint destruction.
Georg Schett, Steven L. Teitelbaum
openaire +3 more sources
Mesoporous bioactive glass/e-polycaprolactone scaffolds promote bone regeneration in osteoporotic sheep [PDF]
Acta Biomaterialia 90 (2019) 3693-402, 2021 Macroporous scaffolds made of a SiO2-CaO-P2O5 mesoporous bioactive glass (MBG) and epolycaprolactone (PCL) have been prepared by robocasting. These scaffolds showed an excellent in vitro biocompatibility in contact with osteoblast like cells (Saos 2) and osteoclasts derived from RAW 264.7 macrophages.
arxiv +1 more source
Incorporation and effects of mesoporous SiO2-CaO nanospheres loaded with ipriflavone on osteoblast/osteoclast cocultures [PDF]
Eur. J. Pharm. Biopharm. 133, 258-268 (2018), 2021 Mesoporous nanospheres in the system SiO2-CaO (NanoMBGs) with a hollow core surrounded by a radial arrangement of mesopores were characterized, labeled with FITC (FITC-NanoMBGs) and loaded with ipriflavone (NanoMBG-IPs) in order to evaluate their incorporation and their effects on both osteoblasts and osteoclasts simultaneously and maintaining the ...
arxiv +1 more source
Osteoclast activated FoxP3+ CD8+ T-cells suppress bone resorption in vitro. [PDF]
PLoS ONE, 2012 Osteoclasts are the body's sole bone resorbing cells. Cytokines produced by pro-inflammatory effector T-cells (T(EFF)) increase bone resorption by osteoclasts.
Zachary S Buchwald +4 more
doaj +1 more source
Centrosome clustering control in osteoclasts through CCR5-mediated signaling
Scientific Reports, 2023 Osteoclasts uniquely resorb calcified bone matrices. To exert their function, mature osteoclasts maintain the cellular polarity and directional vesicle trafficking to and from the resorbing bone surface.
Ji-Won Lee +10 more
doaj +1 more source
Automated Quantification of Human Osteoclasts Using Object Detection
Frontiers in Cell and Developmental Biology, 2022 A balanced skeletal remodeling process is paramount to staying healthy. The remodeling process can be studied by analyzing osteoclasts differentiated in vitro from mononuclear cells isolated from peripheral blood or from buffy coats.
Sampsa Kohtala +9 more
doaj +1 more source
Origin of Osteoclasts: Osteoclast Precursor Cells
Journal of Bone Metabolism, 2023 Osteoclasts are multinucleated bone-resorbing cells and a key player in bone remodeling for health and disease. Since the discovery of osteoclasts in 1873, the structure and function of osteoclasts and the molecular and cellular mechanisms of osteoclastogenesis have been extensively studied.
Jefferson Tsai +4 more
openaire +2 more sources
The response of pre-osteoblasts and osteoclasts to gallium containing mesoporous bioactive glasses [PDF]
Acta Biomaterialia. 76, 333-343 (2018), 2021 Mesoporous bioactive glasses (MBGs) in the system SiO2-CaO-P2O5-Ga2O3 have been synthesized by the evaporation induced self-assembly method and subsequent impregnation with Ga cations. Two different compositions have been prepared and the local environment of Ga(III) has been characterized using 29Si, 71Ga and 31P NMR analysis, demonstrating that Ga ...
arxiv +1 more source