Results 21 to 30 of about 111,801 (276)
Genetic ablation of CD68 results in mice with increased bone and dysfunctional osteoclasts.
PLoS ONE, 2011 CD68 is a member of the lysosome associated membrane protein (LAMP) family that is restricted in its expression to cells of the monocyte/macrophage lineage. This lineage restriction includes osteoclasts, and, while previous studies of CD68 in macrophages
Jason W Ashley +5 more
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Arthritis-associated osteoclastogenic macrophage, AtoM, as a key player in pathological bone erosion
Inflammation and Regeneration, 2022 Osteoclasts are myeloid lineage cells with a unique bone-destroying ability that maintains bone homeostasis together with bone formation by osteoblasts.
Tomoya Agemura +4 more
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Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro [PDF]
, 2013 Peer reviewedPublisher ...
Pappalardo, A., Thompson, K.
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Osteoclasts control osteoblast chemotaxis via PDGF-BB/PDGF receptor beta signaling. [PDF]
PLoS ONE, 2008 Bone remodeling relies on the tightly regulated interplay between bone forming osteoblasts and bone digesting osteoclasts. Several studies have now described the molecular mechanisms by which osteoblasts control osteoclastogenesis and bone degradation ...
Maria Arantzazu Sanchez-Fernandez +4 more
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The effect of brown algae (Sargassum sp.) gel on the number of osteoclasts in periodontitis rats
Padjadjaran Journal of Dentistry, 2022 Introduction: Alveolar bone resorption in periodontitis is caused by increased activation of osteoclasts, causing an imbalance of bone remodeling.
Muhamat Muhtar S. Abdurrohman +2 more
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Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]
, 2012 Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
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Frontiers in Cell and Developmental Biology, 2020 Tumor necrosis factor-alpha (TNF-α) promotes osteoclasts differentiation to enhance bone resorption and inhibits osteoblasts differentiation to impair bone formation, which plays a central role in the development of postmenopausal osteoporosis (PMOP ...
Zhuochao Liu +9 more
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INTRAVASCULAR OSTEOCLASTS [PDF]
The Journal of Bone and Joint Surgery. British volume, 1957 1. In five out of eleven cases of osteoclastoma it was found that osteoclasts were present inside clearly defined blood vessels either within the tumours or in the tissues immediately surrounding the tumours. In two further cases it was found that osteoclasts protruded into the vessels although they were not lying free within the vessels. 2.
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Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts [PDF]
, 2019 Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission.
Atkinson, Emily G. +7 more
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BMC Musculoskeletal Disorders, 2010 Background Bone resorption is initiated by osteoclastic acidification of the resorption lacunae. This process is mediated by secretion of protons through the V-ATPase and chloride through the chloride antiporter ClC-7.
Boutin Jean A +5 more
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