Results 81 to 90 of about 31,027 (248)
Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence
JCI Insight, 2020 In aging mice, osteoclast number increases in cortical bone but declines in trabecular bone, suggesting that different mechanisms underlie age-associated bone loss in these 2 compartments.
Ha-Neui Kim +13 more
semanticscholar +1 more source
Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype
Cancers, 2021 Simple Summary Metastatic lesions in bone tissue are a common complication in breast and prostate cancer patients, accounting for the larger part of pain and suffering in late-stage cancer.
S. W. Verbruggen +7 more
semanticscholar +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2022 Background and Objectives: The ability of ovarian stem cells (OSCs) to differentiate into oocyte-like and theca cells may lead to major advances in infertility treatment.
Samane Adib
doaj
Biochemistry and Biophysics Reports, 2017 Osteocytes play important roles in controlling bone quality as well as preferential alignment of biological apatite c-axis/collagen fibers. However, the relationship between osteocytes and mechanical stress remains unclear due to the difficulty of three ...
Nao Inaba +4 more
doaj +1 more source
Journal of Orthopaedic Translation, 2020 Background: Although emerging studies have provided evidence that osteocytes are actively involved in fracture healing, there is a general lack of a detailed understanding of the mechanistic pathway, cellular events and expression of markers at different
Man Huen Victoria Choy +8 more
doaj +1 more source
β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor.
Cell Reports, 2018 Exercise has beneficial effects on metabolism and on tissues. The exercise-induced muscle factor β-aminoisobutyric acid (BAIBA) plays a critical role in the browning of white fat and in insulin resistance. Here we show another function for BAIBA, that of
Y. Kitase +8 more
semanticscholar +1 more source
The Effect of Osteocyte Signalling on Osteocyte Apoptosis [PDF]
Proceedings of Surabaya International Physiology Seminar, 2017 Abstract: Background: Physical exercise has been known that is one of the ways to evoke mechanical stimulation that can cause the change of the “strain”. The “strain” itself allows the converted mechanical signal to be a biochemistry that can produce a biological response to bone cells.
Dwi Setiani Sumardiko +2 more
openaire +1 more source
Bioprinting of an osteocyte network for biomimetic mineralization
Biofabrication, 2020 Osteocytes, essential regulators of bone homeostasis, are embedded in the mineralized bone matrix. Given the spatial arrangement of osteocytes, bioprinting represents an ideal method to biofabricate a 3D osteocyte network with a suitable surrounding ...
Yiqi Yang +6 more
semanticscholar +1 more source
Glucocorticoids and osteocyte autophagy [PDF]
Bone, 2013 Glucocorticoids are used for the treatment of inflammatory and autoimmune diseases. While they are effective therapy, bone loss and incident fracture risk are high. While previous studies have found GC effects on both osteoclasts and osteoblasts, our work has focused on the effects of GCs on osteocytes.
Wei, Yao +3 more
openaire +2 more sources
Scientific Reports, 2021 Osteocytes differentiated from osteoblasts play significant roles as mechanosensors in modulating the bone remodeling process. While the well-aligned osteocyte network along the trabeculae with slender cell processes perpendicular to the trabeculae ...
Jeonghyun Kim +3 more
doaj +1 more source