Results 131 to 140 of about 91,170 (312)

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

Development of an early estimation method for predicting later osteogenic differentiation activity of rat mesenchymal stromal cells from their attachment areas

Science and Technology of Advanced Materials, 2012
Cell morphology has received considerable attention in recent years owing to its possible relationship with cell functions, including proliferation, differentiation, and migration. Recent evidence suggests that extracellular environments can also mediate
Kan Cheng, Motohiro Hirose, Xiupeng Wang, Yu Sogo, Atsushi Yamazaki and Atsuo Ito
doaj   +1 more source

Osteogenic Differentiation of Renal Interstitial Fibroblasts Promoted by lncRNA MALAT1 May Partially Contribute to Randall’s Plaque Formation

, 2021
Zewu Zhu, Fang Huang, Weiping Xia, Huimin Zeng, Meng Gao, Yongchao Li, Feng Zeng, Cheng He, Jinbo Chen, Zhiyong Chen, Yang Li, Yu Cui, Hequn Chen   +12 more
openalex   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Identification of long non‑coding RNAs expressed during the�osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells obtained from patients with ONFH

, 2020
Tao Li, Ke Xiao, Yingxing Xu, Yuanzhong Ren, Yingzhen Wang, Haining Zhang, Xisheng Weng, Yaping Jiang   +7 more
openalex   +2 more sources

Intrinsically Cross‐Linked ECM‐Like Multilayers for BMP‐2 Delivery Promote Osteogenic Differentiation of Cells [PDF]

, 2023
Reema Anouz, Tamaradobra Selekere, Adrian Hautmann, Catharina Husteden, Matthias Menzel, Christian Woelk, Christian E.H. Schmelzer, Thomas Groth   +7 more
openalex   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Y‐Box‐Binding Protein 1 Facilitates the Proliferation and Osteogenic Differentiation of Periodontal Ligament Stem Cells Through the Transcriptional Activation of FGF2‐Mediated Akt/GSK3β/β‐Catenin Signaling

Kaohsiung Journal of Medical Sciences
Periodontal ligament stem cells (PDLSCs) are derived from periodontal tissue and can differentiate into osteoblasts, which are ideal materials for alveolar bone repair and periodontal tissue regeneration. In this study, we aimed to explore the effects of
Yun‐Hao Xi, Chang‐Shun Li, Pin‐Lin Wu, Xiao‐Yang Zhou, Qian‐Wen Li, Cheng‐Hui Shen   +5 more
doaj   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

MicroRNA-21 regulates Osteogenic Differentiation of Periodontal Ligament Stem Cells by targeting Smad5 [PDF]

, 2017
Fulan Wei, Shuangyan Yang, Qingyuan Guo, Xin Zhang, Dapeng Ren, Tao Lv, Xin Xu   +6 more
openalex   +1 more source