Results 201 to 210 of about 148,060 (339)

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Lipus Enhances Osteogenic Differentiation Of Pdlscs Via Wnt7b/Β-Catenin Pathway

Yang Li
openalex   +1 more source

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

Advanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen, Qing Zhao, Wentao Fu, Weixian Chen, Xiaoqian Zhang, Gaiying Ye, Qinglei Meng, Liyuan Shao, Qian Ma, Lin Zhao, Ying Zhao, Weihua Guo   +11 more
wiley   +1 more source

The effects of nanopillar and nanopit arrays on the morphology and osteogenic differentiation of adipose-derived stem cells. [PDF]

Appl Microsc
Kang J, Yun YS, Kang EH, Lee J, Jeon DJ, Ji S, Kim YO, Yun IS, Yeo JS.   +8 more
europepmc   +1 more source

Additional file 3 of LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4

, 2022
Hongwei Gao, Hui Dong, Jiachun Zheng, Xufeng Jiang, Mingzhi Gong, Le Hu, Jinshan He, Yongxiang Wang   +7 more
openalex   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Hydroxyapatite-Mediated Mechanical Modulation of GelMA Hydrogels Influences Osteogenic Differentiation of 3D Spheroids. [PDF]

Gels
Amarbayasgalan N, Kim JH, Koh WG, Muthuramalingam K, Lee HJ.   +4 more
europepmc   +1 more source

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

FTO-mediated m6A modification regulates the osteogenic differentiation of ADSCs by targeting FOXO1. [PDF]

Stem Cell Res Ther
Wang Z, Wen S, Li H, Wang X, Guo S, Yang S.   +5 more
europepmc   +1 more source

Additional file 1 of Comprehensive analysis of lncRNA-miRNA-mRNA networks during osteogenic differentiation of bone marrow mesenchymal stem cells

, 2022
Jialin Liu, Yuan Yao, Jinyong Huang, Hao Sun, Yixuan Pu, Mengting Tian, Meijie Zheng, Huiyu He, Zheng Li   +8 more
openalex   +1 more source