Results 41 to 50 of about 148,060 (339)
Alkaline Phosphatase-Mimicking Peptide Nanofibers for Osteogenic Differentiation [PDF]
Biomacromolecules, 2015 Recognition of molecules and regulation of extracellular matrix synthesis are some of the functions of enzymes in addition to their catalytic activity. While a diverse array of enzyme-like materials have been developed, these efforts have largely been confined to the imitation of the chemical structure and catalytic activity of the enzymes, and it is ...
Gulseren G. +5 more
openaire +5 more sources
Stem Cell Research & Therapy, 2022 Background Circular RNAs (circRNAs) are a new type of stable noncoding RNA and have been proven to play a crucial role in osteoporosis. This study explored the role and mechanism of hsa_circ_0001485 in osteogenic differentiation.
Shan-Chuang Chen +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Long noncoding RNA (lncRNA) is a noncoding RNA with a length of more than 200 bases. It plays an important role in the occurrence and development of diseases. Research on lncRNAs has received increasing attention.
Haitao Wang +4 more
doaj +1 more source
Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]
, 2017 Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna +6 more
core +2 more sources
Induction of Osteogenic Differentiation by Hedgehog Proteins
Biochemical and Biophysical Research Communications, 1997 In this study we asked whether members of the hedgehog gene family are involved in osteogenesis. C3H10T1/2 cells and MC3T3-E1 cells expressed the putative hedgehog receptor patched (Ptc) gene. Medium conditioned by chicken embryo fibroblast cultures expressing either Indian hedgehog or Sonic hedgehog stimulated alkaline phosphatase (APase) activity in ...
T, Nakamura +11 more
openaire +2 more sources
Investigation of the limits of nanoscale filopodial interactions [PDF]
, 2014 Mesenchymal stem cells are sensitive to changes in feature height, order and spacing. We had previously noted that there was an inverse relationship between osteoinductive potential and feature height on 15-, 55- and 90 nm-high titania nanopillars, with ...
Dalby, Matthew J. +5 more
core +3 more sources
Cellular Physiology and Biochemistry, 2014 Background/Aims: The aim of this study was to analyze the effect of BMP2 on osteogenic differentiation of human adipose tissue-derived stromal cells (hADSCs).
Sun Young Lee +5 more
doaj +1 more source
Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling [PDF]
, 2012 Tissue inhibitor of metalloproteinases 1 (TIMP-1) is a matrix metalloproteinase (MMP)-independent regulator of growth and apoptosis in various cell types.
Avalos +42 more
core +1 more source
Dchs1-Fat4 regulation of osteogenic differentiation in mouse [PDF]
Development, 2019 ABSTRACT In human, mutations of the protocadherins FAT4 and DCHS1 result in Van Maldergem syndrome, which is characterised, in part, by craniofacial abnormalities. Here, we analyse the role of Dchs1-Fat4 signalling during osteoblast differentiation in mouse.
Ivan Crespo-Enriquez +13 more
openaire +5 more sources
Frontiers in Endocrinology, 2021 The osteogenic differentiation capacity of senescent bone marrow mesenchymal stem cells (MSCs) is reduced. p53 not only regulates cellular senescence but also functions as a negative regulator in bone formation.
Chao Xia +5 more
doaj +1 more source