Results 41 to 50 of about 138,476 (311)
Frontiers in Cell and Developmental Biology, 2021 Long noncoding RNA (lncRNA) is a noncoding RNA with a length of more than 200 bases. It plays an important role in the occurrence and development of diseases. Research on lncRNAs has received increasing attention.
Haitao Wang +4 more
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Mesenchymal Stem Cell Spheroids Retain Osteogenic Phenotype Through α2β1 Signaling. [PDF]
, 2016 Unlabelled: The induction of mesenchymal stem cells (MSCs) toward the osteoblastic lineage using osteogenic supplements prior to implantation is one approach under examination to enhance their bone-forming potential.
Harvestine, Jenna N +4 more
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Prospective isolation of human bone marrow stromal cell subsets: a comparative study between Stro-1-, CD146- and CD105-enriched populations [PDF]
, 2014 Stro-1 has proved an efficacious marker for enrichment of skeletal stem and progenitor cells although isolated populations remain heterogeneous, exhibiting variable colony-forming efficiency and osteogenic differentiation potential. The emerging findings
Gothard, David +3 more
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Stem Cell Research & Therapy, 2022 Background Circular RNAs (circRNAs) are a new type of stable noncoding RNA and have been proven to play a crucial role in osteoporosis. This study explored the role and mechanism of hsa_circ_0001485 in osteogenic differentiation.
Shan-Chuang Chen +5 more
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Induction of Osteogenic Differentiation by Hedgehog Proteins
Biochemical and Biophysical Research Communications, 1997 In this study we asked whether members of the hedgehog gene family are involved in osteogenesis. C3H10T1/2 cells and MC3T3-E1 cells expressed the putative hedgehog receptor patched (Ptc) gene. Medium conditioned by chicken embryo fibroblast cultures expressing either Indian hedgehog or Sonic hedgehog stimulated alkaline phosphatase (APase) activity in ...
T, Nakamura +11 more
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Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]
, 2019 The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole +5 more
core +1 more source
Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing [PDF]
, 2020 Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing.
Brinkman, Antonia Clara Katharina +10 more
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Dchs1-Fat4 regulation of osteogenic differentiation in mouse [PDF]
Development, 2019 ABSTRACT In human, mutations of the protocadherins FAT4 and DCHS1 result in Van Maldergem syndrome, which is characterised, in part, by craniofacial abnormalities. Here, we analyse the role of Dchs1-Fat4 signalling during osteoblast differentiation in mouse.
Ivan Crespo-Enriquez +13 more
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Cellular Physiology and Biochemistry, 2014 Background/Aims: The aim of this study was to analyze the effect of BMP2 on osteogenic differentiation of human adipose tissue-derived stromal cells (hADSCs).
Sun Young Lee +5 more
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Differentiated osteoblasts derived decellularized extracellular matrix to promote osteogenic differentiation [PDF]
Biomaterials Research, 2018 Abstract Background The extracellular matrix (ECM) can directly or indirectly influence on regulation of cell functions such as cell adhesion, migration, proliferation and differentiation. The cell derived ECM (CD-ECM) is a useful in vitro model for studying the comprehensive functions of CD-ECM because it maintains a
Jin Jeon, Min Suk Lee, Hee Seok Yang
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