Results 71 to 80 of about 2,318 (174)

Osteoimmunology of Fracture Healing

Current Osteoporosis Reports
Abstract Purpose of Review The purpose of this review is to summarize what is known in the literature about the role inflammation plays during bone fracture healing. Bone fracture healing progresses through four distinct yet overlapping phases: formation of the hematoma, development of the cartilaginous callus ...
Molitoris, Kristin Happ, Huang, Mingjian, Baht, Gurpreet Singh   +2 more
openaire   +2 more sources

Immunotherapy in the Battle Against Bone Metastases: Mechanisms and Emerging Treatments

Pharmaceuticals
Bone metastases are a prevalent complication in advanced cancers, particularly in breast, prostate, and lung cancers, and are associated with severe skeletal-related events (SREs), including fractures, spinal cord compression, and debilitating pain ...
Fatheia N. Hamza, Khalid Said Mohammad
doaj   +1 more source

Temporal dynamics of immune-stromal cell interactions in fracture healing

Frontiers in Immunology
Bone fracture repair is a complex, multi-step process that involves communication between immune and stromal cells to coordinate the repair and regeneration of damaged tissue. In the US, 10% of all bone fractures do not heal properly without intervention,
Christina A. Capobianco, Christina A. Capobianco, Kurt D. Hankenson, Kurt D. Hankenson, Alexander J. Knights   +4 more
doaj   +1 more source

Osteoimmunology in Bone Regeneration [PDF]

BioMed Research International, 2020
Ziqing Li, Puyi Sheng, Chaohong Li, Gongsheng Yuan, Yilun Deng   +4 more
openaire   +2 more sources

Lithium chloride with immunomodulatory function for regulating titanium nanoparticle-stimulated inflammatory response and accelerating osteogenesis through suppression of MAPK signaling pathway

International Journal of Nanomedicine, 2019
Chao Yang,* Wei Wang,* Kechao Zhu, Wei Liu, Yao Luo, Xiangwei Yuan, Jiaxing Wang, Tao Cheng, Xianlong Zhang Department of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, People’s Republic of ...
Yang C, Wang W, Zhu K, Liu W, Luo Y, Yuan X, Wang J, Cheng T, Zhang X   +8 more
doaj  

Three Different Involvements in a Case of Ulcerative Colitis: Bilateral Femoral Head Avascular Necrosis, Spondylodiscitis and Spondyloarthropathy

Türk Osteoporoz Dergisi
Avascular necrosis (AVN) is a serious condition that develops as a result of inadequate blood supply to bone tissue. This condition is usually associated with trauma, long-term steroid use, or systemic diseases.
Tuba Erdem Sultanoğlu, Sümeyye Uçar Meydan   +1 more
doaj   +1 more source

HIF-1α at the intersection of hypoxia, ferroptosis-associated stress, and cell death crosstalk in osteomyelitis

Frontiers in Cell and Developmental Biology
Osteomyelitis is a severe inflammatory disease of bone tissue primarily caused by bacterial infections, most commonly Staphylococcus aureus. Its complex pathophysiology creates a unique hypoxic and inflamed microenvironment, which leads to the ...
Jinglin Li, Jinglin Li, Fuyin Yang, Fuyin Yang, Xuan Deng, Xuan Deng, Yang Yu, Yang Yu, Xianpeng Huang, Xianpeng Huang, Xuxu Yang, Xuxu Yang, Lidan Yang, Lidan Yang, Tao Zhang, Huazhang Xiong, Huazhang Xiong   +16 more
doaj   +1 more source

Editorial: New perspectives on osteoclasts in health and disease

Frontiers in Cell and Developmental Biology, 2022
Maria-Bernadette Madel, Enrico Iaccino, Claudine Blin-Wakkach, Stefania Mariggiò   +3 more
doaj   +1 more source

Unveiling the efficacy predictors and potential mechanisms of Semen Cuscutae against osteoporosis via machine learning and meta-analysis: a preclinical study

Frontiers in Immunology
PurposeTo systematically evaluate the anti-osteoporotic efficacy and underlying mechanisms of Semen Cuscutae and to explore potential experimental factors associated with treatment efficacy using an integration of meta-analysis and machine learning (ML ...
Bo Dong, Rui Tang, Rui Tang, Dongping Wan, Haoxiang Yuan, Chuan Leng, Rui Wang, Feilong Li, Junbo He, Yong Peng, Shihang Cao, Baohui Wang   +11 more
doaj   +1 more source

MiR-1a-3p/Fcgr4-dependent osteoclast activation regulates pathological bone loss

Frontiers in Immunology
IntroductionOsteoporosis is a systemic metabolic disease characterized by disrupted homeostasis between osteoclast-mediated bone resorption and osteoblast-mediated bone formation.
Jiayao Zhang, Yun Zhai, Liang He, Yunping Song, Mingxuan Lu, Xuerui Xiang, Jiehong Huang, Jinyin Huang, Weiqing Tian, Yue Zhao, Shuxian Lin, Weicai Liu   +11 more
doaj   +1 more source