Results 61 to 70 of about 44,473 (251)
, 2018 Introduction: decreased blood flow to the head of femur is a degenerative process leading to cell death and eventually to osteonecrosis. It occurs mostly in people aged 20-40 and is a common presentation for orthopedic surgery consultation. The surgeons usually decide management plan on a case basis, and depending on the age of the patient, gender ...
openaire +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu +21 more
wiley +1 more source
Multifocal Osteonecrosis Secondary to Chronic Alcohol Ingestion
Case Reports in Orthopedics, 2015 Multifocal osteonecrosis is a relatively rare disorder with an estimated incidence of around 3% among patients diagnosed as having osteonecrosis. Multifocal osteonecrosis is caused by the several conditions including corticosteroid treatment, coagulation
Kazu Matsumoto +2 more
doaj +1 more source
Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits [PDF]
, 2008 Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits
Hausdorf, J. +6 more
core +1 more source
Health Care Science, EarlyView.This study found that the degree of femoral head sagittal displacement is linked to the risk of internal fixation failure in femoral neck fracture. Measurements of the sagittal tilt angle of the femoral head (STAFH) using CT‐3D imaging showed high reliability (ICC = 0.97, 95% CI: 0.96–0.98). Patients with excessive sagittal displacement (anterior tilt ≥
Lei Shi +7 more
wiley +1 more source
Toxicities in long‐term survivors of head and neck cancer—A multi‐national cross‐sectional analysis
International Journal of Cancer, EarlyView.What's New? Cancer treatments frequently have toxic effects on the body, and these toxicities may cause long‐term health issues. Here, the authors report the results of a large, international study to evaluate long‐term toxicities of treatment for head and neck cancer (HNC).
Katherine J. Taylor +37 more
wiley +1 more source
Haematologica, 2015 Osteonecrosis and decline of bone density are serious side effects during and after treatment of childhood acute lymphoblastic leukemia. It is unknown whether osteonecrosis and low bone density occur together in the same patients, or whether these two ...
Marissa A.H. den Hoed +14 more
doaj +1 more source
Biological evaluations of novel 2,3,3-Trisphosphonate in osteoclastic and osteoblastic activities [PDF]
, 2017 Bisphosphonates (BPs) are the first line treatment for many bone diseases including hypercalcimia associated with bone malignancies. In this paper, we introduce a new analogue of bisphosphonate called the 2,3,3-Trisphosphonate (2,3,3-TriPP) that was ...
Boccaccini, Aldo R. +4 more
core +3 more sources
Pathophysiology of Osteonecrosis of the Jaws [PDF]
Oral and Maxillofacial Surgery Clinics of North America, 2015 Osteonecrosis of the jaw (ONJ) is a multifactorial disease in patients with primary or metastatic bone malignancy or osteoporosis undergoing systemic antiresorptive therapy, where pathophysiology has not yet been fully determined. The staging of ONJ is based on severity of symptoms and extent of clinical and radiographic findings.
Aghaloo, Tara +2 more
openaire +5 more sources