Results 61 to 70 of about 32,260 (226)

Osteoprotegerin as a biomarker of geriatric frailty syndrome

open access: yesAging, 2019
The lack of a univocal definition of frailty, a condition frequently found in the elderly population which is correlated with an increased risk of mortality, has prompted the search for clinical and laboratory parameters associated with this condition ...
A. Valentini   +4 more
semanticscholar   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

The Role of Osteoprotegerin as a Cardioprotective Versus Reactive Inflammatory Marker: the Chicken or the Egg Paradox

open access: yesBalkan Medical Journal, 2018
Cardiovascular disease is one of the most frequent causes of mortality and morbidity worldwide. Several variables have been identified as risk factors for cardiovascular disease.
Flora Özkalaycı   +4 more
semanticscholar   +1 more source

Adverse Outcome Pathways Applied to Space Radiation Research

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Long‐duration spaceflight exposes astronauts to various stressors that can alter human physiology, potentially causing immediate and long‐term health effects. These stressors can damage biomolecules, cells, tissues, and organs, leading to adverse outcomes.
Vinita Chauhan   +18 more
wiley   +1 more source

Probiotic consumption reduces alveolar bone loss and kidney damage in pregnant rats with experimental periodontitis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre   +10 more
wiley   +1 more source

Osteoporosis and polymorphisms of osteoprotegerin gene in postmenopausal women – a pilot study

open access: yesRheumatology, 2016
Objectives: Osteoprotegerin (OPG) has an important role in bone remodeling, and it has been proposed that the OPG gene might be a candidate gene for osteoporosis predisposition.
Selma Cvijetic   +5 more
doaj   +1 more source

Metformin reverses periodontal destruction caused by experimental periodontitis by inhibiting interleukin‐1β activity

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis is a destructive disease that affects periodontal tissue. While current research focuses on disease management, research on tissue repair remains limited. Metformin, a first‐line medication for diabetes treatment, has positive effects on bone health in nondiabetic patients.
Zhao Wang   +10 more
wiley   +1 more source

The effect of non‐surgical periodontal treatment on Dickkopf‐1 and secreted Frizzled‐Related Protein 5 levels

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Recent advancements in bone tissue biomarker research have identified 2 promising molecules: Dickkopf‐1 and secreted Frizzled‐Related Protein 5. This study aims to evaluate the levels of these biomarkers in gingival crevicular fluid in periodontal health, gingivitis, and periodontitis and to assess the effects of non‐surgical ...
Sukran Acipinar, Kubilay Baris
wiley   +1 more source

Fabrication of Lithium/Strontium‐Releasing Smart Bioactive Glasses with Anti‐Inflammatory and Osteogenic Effects Tailored to Pathological Stages

open access: yesMacromolecular Bioscience, EarlyView.
Bioactive glasses with controllable dual ion release capability are developed to aid bone regeneration. The bioactive glasses rapidly release lithium ions that exert an anti‐inflammatory effect, suppressing inflammation after bone injury. Simultaneously, the bioactive glasses slowly release strontium ions, which support bone formation by suppressing ...
Hirohiko Sakai   +6 more
wiley   +1 more source

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