Results 61 to 70 of about 53,476 (305)

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Effect of anatomical location (mandible vs maxilla) of dental implants on the BMP-2, BMP-7, sRANKL and OPG levels in periimplant crevicular fluid during osseointegration. A pilot study

Selcuk Dental Journal, 2019
Background:The aim of this study was to investigate levels of bone morphogenetic protein-2 (BMP-2), BMP-7, soluble receptor activator of nuclear factor-kB ligand (sRANKL) and osteoprotegerin (OPG) in the peri-implant crevicular fluid (PICF) of  implants ...
Mehmet Sağlam, Doğan Dolanmaz, Emrah Koçak, Burcu Poyraz, Özgür İnan, Niyazi Dündar, Sema Hakkı   +6 more
doaj   +1 more source

Effects of RANKL-Targeted Therapy in Immunity and Cancer. [PDF]

, 2014
The role of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK system is well characterized within bone, where RANKL/RANK signaling mediates osteoclastogenesis and bone resorption.
Cheng, Michael L, Fong, Lawrence
core   +2 more sources

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

Nature Communications, 2019
Pulmonary arterial hypertension (PAH) is a rare but fatal disease. Current treatments increase life expectancy but have limited impact on the progressive pulmonary vascular remodelling that drives PAH.
N. Arnold, J. Pickworth, L. West, Sarah Dawson, J. Carvalho, H. Casbolt, A. Braithwaite, J. Iremonger, L. Renshall, V. Germaschewski, M. Mccourt, P. Bland-Ward, Hager Kowash, A. Hameed, A. Rothman, M. Frid, A. A. R. Thompson, H. Evans, M. Southwood, N. Morrell, D. Crossman, M. Whyte, K. Stenmark, C. Newman, D. Kiely, D. Kiely, S. Francis, A. Lawrie   +27 more
semanticscholar   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Value of serum osteoprotegerin in the assessment of endothelial dysfunction in obesity

The Egyptian Journal of Internal Medicine
Objective Osteoprotegerin is a member of the tumor necrosis factor receptor superfamily. The study aimed to assess serum osteoprotegerin and endothelial dysfunction relationship in obese non-diabetic subjects.
Ahmed Mohammed Shennawy, Hany William Z. Hanna, Salma Raed, Randa Salam, Sama Ayman   +4 more
doaj   +1 more source

Prognostic Value of Serum Osteoprotegerin Level in Patients With Hepatocellular Carcinoma Following Surgical Resection

Frontiers in Oncology, 2021
BackgroundMultiple studies have reported that tissue or serum osteoprotegerin (OPG) level is a prognostic factor for patients with cancer. However, little is known about the role of serum OPG in hepatocellular carcinoma (HCC).
Chihao Zhang, Jiayun Lin, Xiaochun Ni, Hongjie Li, Lei Zheng, Zhifeng Zhao, Xiaoliang Qi, Haizhong Huo, Xiaolou Lou, Qiang Fan, Meng Luo   +10 more
doaj   +1 more source

Effect of a reduction in glomerular filtration rate after nephrectomy on arterial stiffness and central hemodynamics: rationale and design of the EARNEST study [PDF]

, 2014
Background: There is strong evidence of an association between chronic kidney disease (CKD) and cardiovascular disease. To date, however, proof that a reduction in glomerular filtration rate (GFR) is a causative factor in cardiovascular disease is ...
Alam, Arena, Bahous, Benetos, Blacher, Blacher, Boudville, Briet, Charles J. Ferro, Charles R. Tomson, Chue, Chue, Daniel Zehnder, DeLoach, Doucende, Edwards, Eknoyan, Faul, Fehrman-Ekholm, Foley, Forbat, Frimodt-Moller, Garg, Go, Groenink, Grothues, Guerin, Hametner, Ian B. Wilkinson, Ibrahim, Jackson, John R. Cockcroft, Jonathan N. Townend, Kasiske, Krohn, Landray, Lang, Laurent, Laurie A. Tomlinson, Levey, Lewington, Luzardo, Maceira, Madero, Mafham, Mark, Martensson, Matsushita, Michels, Moody, Moody, Myerson, Nagueh, National Kidney Foundation, O'Brien, Patrick B. Mark, Richard P. Steeds, Rook, Rothwell, Savage, Schiffrin, Schiller, Segev, Tavakol, Townsend, Vickery, Wang, Wei, Weiss, Wiesmann, Wilkinson, William E. Moody, Yeon, Young   +73 more
core   +2 more sources

Ontogeny of murine bony semicircular canal form

The Anatomical Record, EarlyView.
Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna, Nathan Jeffery   +1 more
wiley   +1 more source

Identification of Predictable Biomarkers in Conjunction to Framingham Risk Score to Predict the Risk for Cardiovascular disease (CVD) in Non Cardiac Subjects [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Although the cardiovascular disease (CVD) burden is rising in different countries, the morbidity and mortality rate is not reduced to much extent because of lack of application of the biomarkers for diagnosing CVD.
Rama Krishna Reddy Y.V., Jaideep Mahendra, Prema Gurumurthy, Jayamathi, Sai Babu   +4 more
doaj   +1 more source