Results 1 to 10 of about 210,566 (294)

Osteosarcoma of Jaw Masquerading as Calcifying Epithelial Odontogenic Tumour- A Diagnostic Dilemma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Osteogenic osteosarcoma is the most widely recognised primary malignant bone tumour involving particularly the appendicular skeleton. Osteosarcoma of jaw including maxillary and mandibular osteosarcoma accounts for about 7% of cases.
Neha Sethi, Nimisha Devpura, Nitin Khutenta, ML Yadav, Maneesh Vijaywargia   +4 more
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The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

Acta Pharmaceutica Sinica B, 2022
Osteosarcoma is a kind of bone tumor with highly proliferative and invasive properties, a high incidence of pulmonary metastasis and a poor prognosis. Chemotherapy is the mainstay of treatment for osteosarcoma.
Geni Ye, Maohua Huang, Yong Li, Jie Ouyang, Minfeng Chen, Qing Wen, Xiaobo Li, Huhu Zeng, Pei Long, Zepei Fan, Junqiang Yin, Wencai Ye, Dongmei Zhang   +12 more
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The bioinformatic approach identifies PARM1 as a new potential prognostic factor in osteosarcoma

Frontiers in Oncology, 2023
ObjectiveTo explore the key factors affecting the prognosis of osteosarcoma patients.MethodsBased on the GEO dataset and differential expression analysis of normal and osteosarcoma tissues, the gene modules related to the prognosis of osteosarcoma ...
Haijun Feng, Liping Wang, Jie Liu, Shengbao Wang   +3 more
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Long Intergenic Noncoding RNA00265 Enhances Cell Viability and Metastasis via Targeting miR-485-5p/USP22 Axis in Osteosarcoma

Frontiers in Oncology, 2022
Osteosarcoma is one of the bone malignancies in children and adolescents. Long noncoding RNAs (lncRNAs) have been demonstrated to participate in osteosarcoma development and progression.
Ting Chen, Jinxin Liu, He Zhang, Jiatong Li, Guanning Shang   +4 more
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Aberrant Expression of PAFAH1B3 Affects Proliferation and Apoptosis in Osteosarcoma

Frontiers in Oncology, 2021
Osteosarcoma is a major malignant tumor of bone and soft tissue, which is presenting with early metastasis and a high mortality rate. Platelet activating factor acetylhydrolase 1B3 (PAFAH1B3), a cancer-relevant molecular, was found to play a vital role ...
Jian Fan, Yi Yang, Ji-kui Qian, Xin Zhang, Jia-qing Ji, Li Zhang, Shan-zhu Li, Feng Yuan   +7 more
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PKIB involved in the metastasis and survival of osteosarcoma

Frontiers in Oncology, 2022
Osteosarcoma is frequently metastasized at the time of diagnosis in patients. However, the underlying mechanism of osteosarcoma metastasis remains poorly understood.
Rongxue Wan, Rongxue Wan, Gu Yang, Qianzhen Liu, Xiaokang Fu, Zengping Liu, Huilai Miao, Huilai Miao, Huan Liu, Huan Liu, Wenhua Huang, Wenhua Huang, Wenhua Huang   +12 more
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Integrated multiomic analysis and high‐throughput screening reveal potential gene targets and synergetic drug combinations for osteosarcoma therapy

MedComm, 2023
Although great advances have been made over the past decades, therapeutics for osteosarcoma are quite limited. We performed long‐read RNA sequencing and tandem mass tag (TMT)‐based quantitative proteome on osteosarcoma and the adjacent normal tissues ...
Wenchao Zhang, Lin Qi, Zhongyue Liu, Shasha He, Cheng‐zhi Wang, Ying Wu, Lianbin Han, Zhenxin Liu, Zheng Fu, Chao Tu, Zhihong Li   +10 more
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SOX12 Promotes Stem Cell-Like Phenotypes and Osteosarcoma Tumor Growth by Upregulating JAGGED1

Stem Cells International, 2021
SOX12 plays a role in promoting the growth of some tumors; however, its role in osteosarcoma remains unclear. From gene expression omnibus (GEO) and tumor alterations relevant for genomics-driven therapy (TARGET) databases, Kaplan–Meier analyses were ...
Weifei Zhang, Fei Yu, Jian Weng, Yien Zheng, Jianjing Lin, Tiantian Qi, Yihao Wei, Deli Wang, Hui Zeng   +8 more
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AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma

Signal Transduction and Targeted Therapy, 2021
Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Although activator of HSP90 ATPase activity 1 (AHA1) is reported to be a potential oncogene, its role in osteosarcoma progression remains largely unclear ...
Diwei Zheng, Weihai Liu, Wenlin Xie, Guanyu Huang, Qiwei Jiang, Yang Yang, Jiarong Huang, Zihao Xing, Mengling Yuan, Mengning Wei, Yao Li, Junqiang Yin, Jingnan Shen, Zhi Shi   +13 more
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The Role of NR4A1 in the Pathophysiology of Osteosarcoma: A Comprehensive Bioinformatics Analysis of the Single-Cell RNA Sequencing Dataset

Frontiers in Oncology, 2022
Osteosarcoma is a kind of aggressive human malignancy, and the prognosis of the patients with osteosarcoma remains low. Studies have demonstrated that the tumor microenvironment plays a key role in regulating osteosarcoma progression. Recent studies have
Weidong Liu, Yuedong Hao, Xiao Tian, Jing Jiang, Quanhe Qiu   +4 more
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