Results 1 to 10 of about 255,852 (377)

PiRNA hsa_pir_018849 promotes the proliferation and invasion of osteosarcoma cells by regulating the stability of CCN5 mRNA [PDF]

Journal of Orthopaedic Surgery and Research
Background Osteosarcoma is a primary malignant bone tumor and that is predominantly found in adolescents and young adults, and it often occurs during periods of rapid bone growth.
Jiale Huang, Saishuai Yang, Peng Liu, He Jiang, Zhiming Cui, Jiajia Chen   +5 more
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Screening drugs of Anemoside B4 for MFAP4 expression in osteosarcoma in PDTX to increase personalized medicine [PDF]

Discover Oncology
Osteosarcoma is a group of malignant tumors with a variety of histological subtypes and biological characteristics. This type of tumor mainly affects bones and soft tissues and is commonly found in children and young people.
Lei Zhang, Lijuan Zeng, Jing Zhang, Zhiwei He, Xiaozhou Liu   +4 more
doaj   +2 more sources

Osteosarcoma of Jaw Masquerading as Calcifying Epithelial Odontogenic Tumour- A Diagnostic Dilemma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Osteogenic osteosarcoma is the most widely recognised primary malignant bone tumour involving particularly the appendicular skeleton. Osteosarcoma of jaw including maxillary and mandibular osteosarcoma accounts for about 7% of cases.
Neha Sethi, Nimisha Devpura, Nitin Khutenta, ML Yadav, Maneesh Vijaywargia   +4 more
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The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

Acta Pharmaceutica Sinica B, 2022
Osteosarcoma is a kind of bone tumor with highly proliferative and invasive properties, a high incidence of pulmonary metastasis and a poor prognosis. Chemotherapy is the mainstay of treatment for osteosarcoma.
Geni Ye, Maohua Huang, Yong Li, Jie Ouyang, Minfeng Chen, Qing Wen, Xiaobo Li, Huhu Zeng, Pei Long, Zepei Fan, Junqiang Yin, Wencai Ye, Dongmei Zhang   +12 more
doaj   +1 more source

Long Intergenic Noncoding RNA00265 Enhances Cell Viability and Metastasis via Targeting miR-485-5p/USP22 Axis in Osteosarcoma

Frontiers in Oncology, 2022
Osteosarcoma is one of the bone malignancies in children and adolescents. Long noncoding RNAs (lncRNAs) have been demonstrated to participate in osteosarcoma development and progression.
Ting Chen, Jinxin Liu, He Zhang, Jiatong Li, Guanning Shang   +4 more
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The bioinformatic approach identifies PARM1 as a new potential prognostic factor in osteosarcoma

Frontiers in Oncology, 2023
ObjectiveTo explore the key factors affecting the prognosis of osteosarcoma patients.MethodsBased on the GEO dataset and differential expression analysis of normal and osteosarcoma tissues, the gene modules related to the prognosis of osteosarcoma ...
Haijun Feng, Liping Wang, Jie Liu, Shengbao Wang   +3 more
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Aberrant Expression of PAFAH1B3 Affects Proliferation and Apoptosis in Osteosarcoma

Frontiers in Oncology, 2021
Osteosarcoma is a major malignant tumor of bone and soft tissue, which is presenting with early metastasis and a high mortality rate. Platelet activating factor acetylhydrolase 1B3 (PAFAH1B3), a cancer-relevant molecular, was found to play a vital role ...
Jian Fan, Yi Yang, Ji-kui Qian, Xin Zhang, Jia-qing Ji, Li Zhang, Shan-zhu Li, Feng Yuan   +7 more
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PKIB involved in the metastasis and survival of osteosarcoma

Frontiers in Oncology, 2022
Osteosarcoma is frequently metastasized at the time of diagnosis in patients. However, the underlying mechanism of osteosarcoma metastasis remains poorly understood.
Rongxue Wan, Rongxue Wan, Gu Yang, Qianzhen Liu, Xiaokang Fu, Zengping Liu, Huilai Miao, Huilai Miao, Huan Liu, Huan Liu, Wenhua Huang, Wenhua Huang, Wenhua Huang   +12 more
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Integrated multiomic analysis and high‐throughput screening reveal potential gene targets and synergetic drug combinations for osteosarcoma therapy

MedComm, 2023
Although great advances have been made over the past decades, therapeutics for osteosarcoma are quite limited. We performed long‐read RNA sequencing and tandem mass tag (TMT)‐based quantitative proteome on osteosarcoma and the adjacent normal tissues ...
Wenchao Zhang, Lin Qi, Zhongyue Liu, Shasha He, Cheng‐zhi Wang, Ying Wu, Lianbin Han, Zhenxin Liu, Zheng Fu, Chao Tu, Zhihong Li   +10 more
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SOX12 Promotes Stem Cell-Like Phenotypes and Osteosarcoma Tumor Growth by Upregulating JAGGED1

Stem Cells International, 2021
SOX12 plays a role in promoting the growth of some tumors; however, its role in osteosarcoma remains unclear. From gene expression omnibus (GEO) and tumor alterations relevant for genomics-driven therapy (TARGET) databases, Kaplan–Meier analyses were ...
Weifei Zhang, Fei Yu, Jian Weng, Yien Zheng, Jianjing Lin, Tiantian Qi, Yihao Wei, Deli Wang, Hui Zeng   +8 more
doaj   +1 more source