Results 101 to 110 of about 134,783 (292)
Advanced Intelligent Discovery, EarlyView.Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz +2 more
wiley +1 more source
Artificial Intelligence for Bone: Theory, Methods, and Applications
Advanced Intelligent Discovery, EarlyView.Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan +3 more
wiley +1 more source
FBXO2 modulates STAT3 signaling to regulate proliferation and tumorigenicity of osteosarcoma cells [PDF]
, 2020 Xunming Zhao +3 more
openalex +1 more source
Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis
Animal Models and Experimental Medicine, EarlyView.This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding +10 more
wiley +1 more source
Scientific ReportsOsteosarcoma is a common primary malignant bone tumor. S100A16 gene was reported to highly expressed in several tumor tissues while the relationship between S100A16 and osteosarcoma remains less well-understood.
Ying-Ying Xiang +5 more
doaj +1 more source
Acoustofluidic Patterning for Improved Microtissue Histology
Advanced NanoBiomed Research, EarlyView.Microtissue histology is widely used to characterize microtissue phenotype and morphology. However, conventional microtissue histology workflows are inefficient and time‐consuming. This work introduces a novel embedding technique that uses acoustofluidics to improve the efficiency of microtissue histology and reduce the time required for data analysis.
Dhananjay V. Deshmukh +13 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.This study presents a multifunctional Baghdadite ceramic implant integrating doxorubicin‐loaded liposomes via ion‐assisted plasma polymer coating for localized osteosarcoma therapy. The platform enables drug retention, sustained release, tumor cell inhibition, osteoconductivity, and antibacterial activity, offering a mechanically robust strategy for ...
Sally Kortam +8 more
wiley +1 more source
Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs
The Anatomical Record, EarlyView.Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille +6 more
wiley +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source