Results 131 to 140 of about 241,082 (329)
, 2020 A small portion of a tissue defines a microstate in gene expression space. Mutations, epigenetic events or external factors cause microstate displacements which are modeled by combining small independent gene expression variations and large Levy jumps ...
Gonzalez, Augusto +2 more
core
Korelasi Ekspresi Ezrin dan CD44 dengan Respons Kemoterapi pada Pasien Osteosarkoma [PDF]
, 2017 Osteosarcoma is the most common Malignant bone tumor in children and young adults. The process of metastasis and recurrence involves several proteins, including ezrin, and CD44 that are shown to be involved in tumor growth,metastasis and recurrence.
KURNIASARI, N. (NILA) +2 more
core
ACSS2/AATF Drives Soluble FasL‐Mediated CD8+ T Cell Apoptosis in Pancreatic Neuroendocrine Tumors
Advanced Science, EarlyView.This study unveils that ACSS2‐driven acetate metabolism fuels histone pan‐acetylation in pancreatic neuroendocrine tumors (PNETs), remodeling the epigenetic landscape. The ACSS2/AATF axis transcriptionally activates soluble FasL (sFasL), which engages Fas receptors on infiltrating CD8+ T cells to trigger caspase‐8/3‐mediated apoptosis.
Qin Dang +14 more
wiley +1 more source
ENHANCED TRITIATED THYMIDINE (3HT) UPTAKE IN OSTEOSARCOMA CELLS IN VITRO BY PATIENT'S OWN SERUM; SUPPRESSION OF 3HT UPTAKE WITH 17B ESTRADIOL (E2) [PDF]
, 1974 Pierce E. Scranton +3 more
openalex +1 more source
Advanced Science, EarlyView.Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei +10 more
wiley +1 more source
Biodegradable Medical Implants: Reshaping Future Medical Practice
Advanced Science, EarlyView.Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia +4 more
wiley +1 more source
Biocompatible Mesoporous Materials for Bone Therapy
Advanced Science, EarlyView.Biocompatible mesoporous materials (BMMs), characterized by high specific surface area, tunable pore size, different shapes and structures, and multidimensional functionalized modifications, have revolutionary applications in treating bone‐related diseases.
Biao Yu +6 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrated that ATG4B translocates from the cytoplasm to the nucleus during energy deficiency. Nuclear ATG4B inhibits DNA repair by interacting with PRMT1. The nuclear ATG4B‐mediated DNA repair defect is significantly exacerbated within acute myeloid leukemia (AML) cells, promoting leukemia progression in an AML mouse model.
Zhenkun Wang +20 more
wiley +1 more source
SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer
Advanced Science, EarlyView.Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang +21 more
wiley +1 more source