Results 51 to 60 of about 255,852 (377)

LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway

Journal of Orthopaedic Surgery and Research, 2022
Background Osteosarcoma is highly malignant. The migration, invasion, and chemoresistance contribute to poor prognosis of osteosarcoma. Research reported that endogenous bornavirus-like nucleoprotein 3 pseudogene (EBLN3P) promotes the progression of ...
Ming-Xia Sun, Hai-Yan An, Yan-Bin Sun, Yan-bao Sun, Bing Bai   +4 more
doaj   +1 more source

Cellular functions and molecular mechanisms of ubiquitination in osteosarcoma

Frontiers in Oncology, 2022
Although some advances have been made in the treatment of osteosarcoma in recent years, surgical resection remains the mainstream treatment. Initial and early diagnosis of osteosarcoma could be very difficult to achieve due to the insufficient ...
Jiaxun Song, Xiaofeng Yuan, Lianhua Piao, Jiawen Wang, Pu Wang, Ming Zhuang, Jie Liu, Zhiwei Liu, Zhiwei Liu   +8 more
doaj   +1 more source

Clinical Features and Outcomes Differ between Skeletal and Extraskeletal Osteosarcoma. [PDF]

, 2014
Background. Extraskeletal osteosarcoma (ESOS) is a rare subtype of osteosarcoma. We investigated patient characteristics, overall survival, and prognostic factors in ESOS. Methods.
Boscardin, W John, DuBois, Steven G, Goldsby, Robert, Matthay, Katherine K, Thampi, Sheila   +4 more
core   +2 more sources

The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model [PDF]

, 2020
2-Methoxyestradiol is one of the natural 17β-estradiol derivatives and a potential novel anticancer agent currently being under evaluation in advanced phases of clinical trials.
Cappello F., Daca A., Gorska-Ponikowska M., Kuban-Jankowska A., Luu H. H., Marino Gammazza A., Wierzbicka J. M., Wozniak M., Zmijewski M. A.   +8 more
core   +1 more source

Bone Microenvironment and Osteosarcoma Metastasis

International Journal of Molecular Sciences, 2020
The bone microenvironment is an ideal fertile soil for both primary and secondary tumors to seed. The occurrence and development of osteosarcoma, as a primary bone tumor, is closely related to the bone microenvironment.
Chaofei Yang, Ye Tian, Fan Zhao, Zhihao Chen, Peihong Su, Yu Li, A. Qian   +6 more
semanticscholar   +1 more source

Axial Multicentric Osteosarcoma in an English Cocker Spaniel [PDF]

, 2016
No abstract ...
Carvalho, S, De Decker, S, Lara-Garcia, A, Leach, J, Parzefall, B, Smith, K C, Terry, R L   +6 more
core   +2 more sources

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma

Frontiers in Oncology, 2020
Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao, Liyan Liu, Aoyu Li, C. Xiang, Ping-Xiao Wang, Hui Li, Tao Xiao   +6 more
semanticscholar   +1 more source

A chondroblastic osteosarcoma of the coronoid process mimicking a fragmented coronoid process in a dog [PDF]

, 2016
A 6-year-old Rhodesian Ridgeback was presented with a 1.5 year history of right forelimb lameness. Clinical, radiological and computed tomographic findings suggested the presence of fragmented medial coronoid process.
Cirkel, Koen, De Rycke, Lieve, Gielen, Ingrid, Rasenberg, Wilhelmus Sebastianus Johannes, van Bree, Henri   +4 more
core   +1 more source

ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma

Cell Death and Disease, 2021
ALKBH5 is the main enzyme for m 6 A-based demethylation of RNAs and it has been implicated in many biological and pathophysiological processes. Here, we aimed to explore the potential involvement of ALKBH5 in osteosarcoma and decipher the underlying ...
Ye Yuan, Gege Yan, Mingyu He, Hong Lei, Linqiang Li, Yang Wang, Xiaoqi He, Guanghui Li, Quan Wang, Yuelin Gao, Zhezhe Qu, Zhongting Mei, Zhihua Shen, Jiaying Pu, Ao Wang, Wei Zhao, Huiwei Jiang, Weijie Du, Lei Yang   +18 more
semanticscholar   +1 more source

CT45A1 promotes the metastasis of osteosarcoma cells in vitro and in vivo through β-catenin

Cell Death and Disease, 2021
Increased expression of cancer/testis antigens (CTAs) is reported in various tumors. However, the unique role of CTAs in tumor genesis has not yet been verified.
Mingxin Wen, Hui Ren, Shouqiang Zhang, Tao Li, Jiefeng Zhang, Peng Ren   +5 more
doaj   +1 more source