Results 131 to 140 of about 13,484 (179)
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Role of Ouabain-Like Factors in Hypertension
Journal of Cardiovascular Pharmacology, 1993Several reports suggest the presence of sodium-potassium pump inhibitor in plasma and various tissues, particularly during volume-expanded state and low-renin hypertension. It has been hypothesized that by inhibiting the cardiovascular muscle-cell Na(+)-K+ pump, this inhibitor can constrict blood vessels, enhance vasoconstriction, and increase cardiac ...
YUAN C +5 more
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Virology, 1978
Abstract The effects of ouabain on Sindbis virus replication in cloned sublines of ouabain-sensitive (B 1 C 4 ) and -resistant (Oua 5 ) Aedes albopictus cells have been studied. The addition of ouabain (0.1 m M ) to B 1 C 4 cells 1 hr after infection reduced the yield of infectious virus 500-fold.
S J, Mento, V, Stollar
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Abstract The effects of ouabain on Sindbis virus replication in cloned sublines of ouabain-sensitive (B 1 C 4 ) and -resistant (Oua 5 ) Aedes albopictus cells have been studied. The addition of ouabain (0.1 m M ) to B 1 C 4 cells 1 hr after infection reduced the yield of infectious virus 500-fold.
S J, Mento, V, Stollar
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Ouabain—The Key to Cardioprotection?
American Journal of Therapeutics, 2014Based on a wealth of mechanistic evidence supported by the fact that ouabain mimics the spleen-liver effect in this article, the hypothesis is established that the endogenous hormone ouabain not only mimics the effects of ischemic preconditioning but also may be an ideal drug for the prevention of ischemic diseases.
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Endogenous Ouabain in Ménière's Disease
Otology & Neurotology, 2010Endogenous Ouabain (EO) has been demonstrated to modulate the activity of Na+, K+ -ATPase. Our purpose was to measure plasma levels of EO in Ménière's Disease (MD) subjects as a possible predisposing factor to developing and maintaining hydrops.Case-control study.University hospital.Thirty-nine MD subjects and 29 controls with a lifetime negative ...
Teggi Roberto +7 more
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Erythrocyte sodium pump stimulation by ouabain and an endogenous ouabain‐like factor
Cell Biochemistry and Function, 2006AbstractCardiac glycosides inhibit the sodium pump. However, some studies suggest that nanomolar ouabain concentrations can stimulate the activity of the sodium pump.In this study, using the Na+/K+‐ATPase of human erythrocytes, we compared the effect of digoxin, ouabain and an ouabain like‐factor (OLF), on 86Rb uptake.Ouabain concentrations below 10−9 ...
Balzan S +5 more
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Microinjection of ouabain into crab single muscle fibers and the mechanism of ouabain potentiation
Canadian Journal of Physiology and Pharmacology, 1980In order to clarify the mechanism of the potentiating effect of ouabain on contraction, a study was made of the effect of microinjection of 1.5 μL of ouabain on contractile responses and 22Na efflux, using single muscle fibers of crab (i–iii), and the results obtained were compared with observations (iv) on frog hearts.
S, Fujino, M, Fujino
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Apical ouabain-sensitive and ouabain-insensitive ATPases in rat colonic epithelium
Acta Histochemica, 2002Active resorption of potassium ions in the colon is mediated by ouabain-sensitive and ouabain-insensitive H,K-ATPases localized in the apical membrane of colonic enterocytes (colonocytes). The present study was performed to investigate distribution patterns of apical ATPases using catalytic histochemistry and immunohistochemistry.
Radomíra, Vagnerová +3 more
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Relationship between ouabain and asthenozoospermia
Journal of Huazhong University of Science and Technology [Medical Sciences], 2014A growing number of researches have shown that ouabain can regulate mammalian sperm function and male reproduction by modulating the sperm motility, capacitation and acrosome reaction in vitro. This study further examined the relationship between ouabain and asthenozoospermia.
Yi-Hong, Yang +4 more
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Modulation of the Immune System by Ouabain
Annals of the New York Academy of Sciences, 2009Ouabain, a known inhibitor of the Na,K‐ATPase, has been shown to regulate a number of lymphocyte functions in vitro and in vivo. Lymphocyte proliferation, apoptosis, cytokine production, and monocyte function are all affected by ouabain. The ouabain‐binding site occurs at the α subunit of the enzyme. The α subunit plays a critical role in the transport
Sandra, Rodrigues-Mascarenhas +5 more
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Zhonghua nan ke xue = National journal of andrology, 2016
Asthenospermia accounts for about 30% of the causes of male infertility. Currently, most drugs for asthenospermia lack specificity and desirable therapeutic efficiency. An insight into the pathogenesis of asthenospermia is important for the development of specific therapies for this disease.
Tong, Pan, Yong-han, Huang
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Asthenospermia accounts for about 30% of the causes of male infertility. Currently, most drugs for asthenospermia lack specificity and desirable therapeutic efficiency. An insight into the pathogenesis of asthenospermia is important for the development of specific therapies for this disease.
Tong, Pan, Yong-han, Huang
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