Results 11 to 20 of about 259,578 (273)

Serum ox-LDL Level is Reduced with the Extent of Stenosis in Coronary Arteries

open access: yesActa Medica Iranica, 2013
Oxidized LDL (ox-LDL) lipoproteins are proposed as important modified particles triggering pro-inflammatory events through receptor-mediated pathways. We evaluated the circulating ox-LDL level on the concept that the chronic immune events may affect ox ...
Mohammad Najafi, Behnam Alipoor
doaj   +4 more sources

Effect of Camellia sinensis on Fat Peroxidation and Ox-LDL in Rats.

open access: yesArchives of Razi Institute, 2021
Green tea (GT) is believed to have antioxidant properties and beneficial effects on the treatment of some diseases. However, few findings were found concerning the impact of GT on oxidative stress. In the present study, the protective influence of GT against the oxidative stress caused by hydrogen peroxide (H2O2) in rats was evaluated.
Abdulaali Azeez, A   +2 more
openaire   +3 more sources

Formononetin protects against ox-LDL-induced endothelial dysfunction by activating PPAR-γ signaling based on network pharmacology and experimental validation

open access: yesBioengineered, 2021
Formononetin (FMNT), a flavonoid identified from the Chinese herb Astragalus membranaceus, possesses anti-inflammatory or anti-oxidative properties in different human diseases.
Baohua Zhang   +8 more
semanticscholar   +1 more source

Store-operated calcium entry involves in regulating the hyperpermeability of endothelial cells induced by ox-LDL

open access: yes陆军军医大学学报, 2023
Objective To explore the effects of store-operated calcium entry(SOCE) on oxidized low-density lipoprotein (ox-LDL)-induced hyperpermeability in human umbilical vein endothelial cells(HUVECs).
KANG Yue   +4 more
doaj   +1 more source

CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis

open access: yesBiological Research, 2021
Background Atherosclerosis (AS) is the most common type in cardiovascular disease. Due to its complex pathogenesis, the exact etiology of AS is unclear. circRNA has been shown to play an essential role in most diseases.
Xiaohao Zhang   +4 more
semanticscholar   +1 more source

LncRNA XIST regulates atherosclerosis progression in ox-LDL-induced HUVECs [PDF]

open access: yesOpen Medicine, 2021
Abstract Long noncoding RNAs (lncRNAs) have been verified as vital regulators in human disease, including atherosclerosis. However, the precise role of X-inactive-specific transcript (XIST) in atherosclerosis remains unclear. The proliferation and apoptosis of human umbilical vein endothelial cells (HUVECs) exposed to low-density ...
Gao Hongmei, Guo Zhaohui
openaire   +3 more sources

Large impact of low concentration oxidized LDL on angiogenic potential of human endothelial cells: a microarray study. [PDF]

open access: yesPLoS ONE, 2012
Oxidized LDL (ox-LDL) is a key factor in atherogenesis. It is taken up by endothelial cells primarily by ox-LDL receptor-1 (LOX-1). To elucidate transcriptional responses, we performed microarray analysis on human coronary artery endothelial cells ...
Magomed Khaidakov   +8 more
doaj   +1 more source

Circ_0002984 induces proliferation, migration and inflammation response of VSMCs induced by ox‐LDL through miR‑326‐3p/VAMP3 axis in atherosclerosis

open access: yesJournal of Cellular and Molecular Medicine, 2021
Atherosclerosis can result in multiple cardiovascular diseases. Circular RNAs (CircRNAs) have been reported as significant non‐coding RNAs in atherosclerosis progression. Dysfunction of vascular smooth muscle cells (VSMCs) is involved in atherosclerosis.
Ruogu Li, Qiliang Jiang, Yue Zheng
semanticscholar   +1 more source

GPR120 Agonist GW9508 Ameliorated Cellular Senescence Induced by ox-LDL [PDF]

open access: yesACS Omega, 2020
Introduction Oxidized low-density lipoprotein (ox-LDL)-induced endothelial senescence is involved in the pathogenesis of atherosclerosis and many cardiovascular diseases. G-protein-coupled receptor 120 (GPR120), a type of orphan G-protein-coupled receptors (GPRs), plays a vital role in mediating anti-inflammatory and insulin-sensitizing effects.
Ruijie Liu   +4 more
openaire   +3 more sources

The lack of association between different LDL‐C levels and oxidized LDL in patients with type 2 diabetes

open access: yesChronic Diseases and Translational Medicine, 2023
Background High concentrations of low‐density lipoprotein cholesterol (LDL‐C) have been a known risk factor for cardiovascular diseases. Also, the role of oxidized LDL (ox‐LDL) in forming atherosclerosis plaque has been proven.
Soghra Rabizadeh   +8 more
doaj   +1 more source

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