Results 91 to 100 of about 25,633 (260)

Density Functional Theory and Experimental Studies of the Molecular, Vibrational, and Crystal Structure of Bis-Oxadiazole-Bis-Methylene Dinitrate (BODN)

, 2018
Density function theory (DFT) and experimental characterization of energetic materials play important roles in understanding molecular structure–property relations and validating models for their predictive capabilities.
Edward F. C. Byrd, Iskander G. Batyrev (5373002), Rose A. Pesce-Rodriguez (4110415), Rosario C. Sausa, Rosario C. Sausa (5287013), Rose A. Pesce-Rodriguez, Iskander G. Batyrev, Edward F. C. Byrd (1463530)   +7 more
core   +1 more source

Exploring Dipolar Dynamics and Ionic Transport in Metal‐Organic Frameworks: Experimental and Theoretical Insights

Advanced Functional Materials, Volume 36, Issue 43, 29 May 2026.
In this study, the interplay of dipolar dynamics and ionic charge transport in MOF compounds is investigated. Synthesizing the novel structure CFA‐25 with integrated freely rotating dipolar groups, local and macroscopic effects, including interactions with Cs cations are explored.
Ralph Freund, Arthur Schulz, Peter Lunkenheimer, Maryana Kraft, Thomas Bergler, Harald Oberhofer, Dirk Volkmer   +6 more
wiley   +1 more source

Advanced design and application for viologen‐based redox devices with customizable functionalities

Responsive Materials, Volume 4, Issue 2, May 2026.
This review examines viologen‐based materials with customizable functionalities achieved through molecular engineering strategies such as side‐chain modification and composite formation. It emphasizes their utility in electrochromic devices, multicolor displays, and energy storage, while discussing stability challenges and outlining future development ...
Yuxin Chang, Yuchen Ge, Luzi Wang, Jinqian Mao, Zhongzhi Qu, Na Li, Dongqi Liu, Jiupeng Zhao   +7 more
wiley   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Triazine‐Based Dual Histone Deacetylase/phosphatidylinositol 3‐kinase Inhibitors for Breast Cancer Therapy

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Breast cancer is the most frequently diagnosed malignancy and a leading cause of cancer‐related mortality among women worldwide. Triple‐negative breast cancer (TNBC) poses a major clinical challenge due to its aggressive nature, limited therapeutic options, and high propensity for drug resistance.
Lara Luzietti, Gustavo Salgado Pires, Ana Ryan, Crisamie Regidor, Matthew Hiller, Danilo Sarti, Tríona Ní Chonghaile, Pedro de Sena Murteira Pinheiro, Damir Varešlija, Daniel Alencar Rodrigues   +9 more
wiley   +1 more source

Synthesis of Oxadiazoles, Thiadiazoles and Triazoles Derived from Benzo[b]thiophene

Molecules, 2005
In this work 3-chloro-2-chlorocarbonylbenzo[b]thiophene (1) was prepared from cinnamic acid and then converted into the acid hydrazide 2. The azomethines 3a-e were prepared from the corresponding aryl aldehydes and the acid hydrazide 2.
N. Rezki, M. Aouad, R. Al-Bayati, A. Sharba   +3 more
doaj   +1 more source

Systematic Review on 1,2,3‐Oxadiazoles, 1,2,4‐Oxadiazoles, and 1,2,5‐Oxadiazoles in the Antimycobacterial Drug Discovery

ChemMedChem
AbstractTuberculosis remains a leading global health threat, exacerbated by the emergence of multi‐drug‐resistant strains. The search for novel therapeutic agents is critical in addressing this challenge. This review systematically summarizes the potential of oxadiazole derivatives as promising candidates in antimycobacterial drug discovery.
openaire   +2 more sources

Aryl-oxadiazole Schiff bases: Synthesis, α-glucosidase in vitro inhibitory activity and their in silico studies

, 2020
α-Glucosidase enzyme is a therapeutic target for diabetes mellitus and its inhibitors play a vital role in the treatment of this disease. A new series of aryl-oxadiazole Schiff bases (1–18) were synthesized and evaluated for α-glucosidase inhibitory ...
H. Ullah, F. Rahim, M. Taha, Raffaqat Hussain, Nida Tabassum, A. Wadood, Mohsan Nawaz, Ashik Mosaddik, Syahrul Imran, Z. Wahab, G. Miana, Kanwal, K. Khan   +12 more
semanticscholar   +1 more source

Bioisosteric replacement of central 1,2,4-oxadiazole ring of high affinity CB2 ligands by regioisomeric 1,3,4-oxadiazole ring

, 2017
It has been reported that bioisosteric replacement of an 1,2,4-oxadiazole ring by an 1,3,4-oxadiazole ring leads to higher polarity, reduced metabolic degradation by human liver microsomes and reduced interaction with hERG channels.
Schepmann, D., Lueg, C., Corinna Lueg, Vries, H. de, Heitman, L.H., Frehland, B., Henk de Vries, Heimann, D., Wunsch, B., Laura H. Heitman, Bastian Frehland, Dominik Heimann, Bernhard Wünsch, Dirk Schepmann   +13 more
core   +1 more source

Coumarin-oxadiazole derivatives: Synthesis and pharmacological properties

, 2020
Coumarin and oxadiazole moieties ubiquitously occur in a wide range of natural products and are valued for their varied and beneficial pharmacological activities.
Smith, Terry K., Bhagwat, Deepak P., Abdul Razak, Nurhayatun S., Sankaranarayanan, Murugesan, Wahab, Roswanira Abdul, Abdul Wahab, Roswanira, Jamalis, Joazaizulfazli, Chander, Subhash   +7 more
core   +1 more source

5-[5-(4-Chlorophenyl)isoxazol-3-yl]-N-phenyl-1,3,4-oxadiazol-2-amine

IUCrData, 2019
The title compound, C17H11ClN4O2, consists of chlorophenyl (A), isoxazolyl (B), oxadiazolyl (C) and phenyl (D) rings with twist angles between the planes through neighbouring rings A/B, B/C and C/D of 14.9 (1), 1.8 (1) and 8.9 (1)° respectively.
Gamal A. El-Hiti, Bakr F. Abdel-Wahab, Emad Yousif, Mohammad Hayal Alotaibi, Amany S. Hegazy, Benson M. Kariuki   +5 more
doaj   +1 more source