Results 81 to 90 of about 10,824 (225)
Synthesis of 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives [PDF]
, 2019 Synthesis of a series of various 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives (7a-7u) have been done. Synthesis of a series of intermediates (3a-3c and 5a-5c) have been also done, ethyl-2-phenoxyacetate (3a), ethyl 2-(2, 4-dichlorophenoxy)acetate ...
Sharma, Neetesh Kumar +2 more
core +2 more sources
Molecules, 2006 (7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide (2) was prepared from (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester (1) and 100% hydrazine hydrate.
Elizabeth Has-Schon +3 more
doaj +1 more source
Journal of the Turkish Chemical Society, Section A: Chemistry, 2020 In this work, synthesis of novel 1,3,4-oxadiazole derivatives were reported. Good molecular properties profile was predicted for the target compounds. In drug likeness prediction, compound 4b and 8b possess the highest score of 0.31 and 0.33, respectively.
Zühal Kılıç Kurt
doaj +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.A new cyanoacetohydrazide derivative was developed as a key intermediate to synthesize diverse 1,3,4‐thiadiazole‐based heterocyclic compounds. The synthesized compounds were structurally confirmed. Several compounds demonstrated strong cytotoxic activity against HePG‐2 and MCF‐7 cancer cell lines, with compounds 17, 18, and 13 exceeding the activity of
Nashwa M. El‐Metwaly +7 more
wiley +1 more source
Design of Energetic Materials Based on Asymmetric Oxadiazole
ChemistryOpen, 2019 A new family of asymmetric oxadiazole based energetic compounds were designed. Their electronic structures, heats of formation, detonation properties and stabilities were investigated by density functional theory.
Prof. Xinghui Jin +4 more
doaj +1 more source
Molecules, 2016 A series of heterocyclic compounds bearing the well-known free radical scavenging 3,4,5-trimethoxybenzyloxy group, was synthesized. The key compound 4-(3,4,5-trimethoxybenzyl-oxy)benzohydrazide was converted into thiosemicarbazide derivatives, which were
Huda. S. Kareem +4 more
doaj +1 more source
4-[4-(4-Amino-1,2,5-oxadiazol-3-yl)-1,2,5-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 The complete molecule of the compound, C(6)H(4)N(8)O(3), is generated by a crystallographic twofold rotation axis that runs through the central ring. The flanking ring is twisted by 20.2 (1)° with respect to the central ring. One of the amino H atoms forms an intra-molecular N-H⋯N hydrogen bond; adjacent mol-ecules are linked by N-H⋯N hydrogen bonds ...
Jia Si-yuan +4 more
openaire +3 more sources
Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II
European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley +1 more source
Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents
Molecules, 2015 New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines.
Muhammed Karabacak +6 more
doaj +1 more source
Aggregate, Volume 7, Issue 6, June 2026.Two novel extended electron‐deficient central cores (Tz‐Qx, Dz‐Qx) with F/Cl‐substituted terminal groups synergistically optimize small molecule acceptors. Tz‐Qx‐4F outperforms Dz‐Qx‐based counterparts, achieving 19.50% PCE (29.3 mA cm−2 JSC) when blended with D18, thus providing valuable insights for designing high‐performance organic solar cell ...
Lan Xie +10 more
wiley +1 more source