Results 81 to 90 of about 25,633 (260)
Journal of the Turkish Chemical Society, Section A: Chemistry, 2020 In this work, synthesis of novel 1,3,4-oxadiazole derivatives were reported. Good molecular properties profile was predicted for the target compounds. In drug likeness prediction, compound 4b and 8b possess the highest score of 0.31 and 0.33, respectively.
Zühal Kılıç Kurt
doaj +1 more source
Synthesis and characterization of new phthalimides and succinimides substituted with 1,3,4-oxadiazole ring [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 A series of new phthalimides and succinimides connected to 1,3,4-oxadiazole moiety were synthesized via multistep synthesis. The first step involved synthesis of six 5- substituted 2- amino-1,3,4-oxadiazoles by oxidative cyclization of substituted ...
Ahlam Marouf Al-Azzawi +1 more
doaj +1 more source
, 2020 Oxadiazoles are important five membered heterocyclic classes of compounds with 2 azo groups and one oxygen in its ring system. It is widely researched as a lead compound for designing potent bioactive agents.
Mohammad Salam +4 more
core
Design of Energetic Materials Based on Asymmetric Oxadiazole
ChemistryOpen, 2019 A new family of asymmetric oxadiazole based energetic compounds were designed. Their electronic structures, heats of formation, detonation properties and stabilities were investigated by density functional theory.
Prof. Xinghui Jin +4 more
doaj +1 more source
Molecules, 2016 A series of heterocyclic compounds bearing the well-known free radical scavenging 3,4,5-trimethoxybenzyloxy group, was synthesized. The key compound 4-(3,4,5-trimethoxybenzyl-oxy)benzohydrazide was converted into thiosemicarbazide derivatives, which were
Huda. S. Kareem +4 more
doaj +1 more source
Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents
Molecules, 2015 New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines.
Muhammed Karabacak +6 more
doaj +1 more source
4-[4-(4-Amino-1,2,5-oxadiazol-3-yl)-1,2,5-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 The complete molecule of the compound, C(6)H(4)N(8)O(3), is generated by a crystallographic twofold rotation axis that runs through the central ring. The flanking ring is twisted by 20.2 (1)° with respect to the central ring. One of the amino H atoms forms an intra-molecular N-H⋯N hydrogen bond; adjacent mol-ecules are linked by N-H⋯N hydrogen bonds ...
Jia Si-yuan +4 more
openaire +3 more sources
Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application
European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley +1 more source
A Review Exploring Therapeutic Effect of 1,3,4-Oxadiazole Compounds
, 2023 There are many synthesized compounds that contain the five-membered aromatic ring 1,3,4-oxadiazole. It is advantageous for 1,3,4-oxadiazole derivatives to have effective binding with various enzymes and receptors in biological systems through numerous ...
Kurup, Shilpa S, Jat, Rakesh Kumar
core +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.A manifold of catalytic reaction paths can operate in the Au(I)‐catalyzed heteroannulation of salicylic amides and alkynes. However, a subtle initial nucleophilic advantage of N versus O and a kinetic bottleneck at an advanced stage of the mechanistic machinery seems to suffice for the reaction to run on a single path and with exquisite selectivity. We
Ioannis Stylianakis +3 more
wiley +1 more source