Results 81 to 90 of about 28,539 (273)

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents

open access: yesMolecules, 2015
New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines.
Muhammed Karabacak   +6 more
doaj   +1 more source

Nonstandard electroconvection in a bent-core oxadiazole material [PDF]

open access: yes, 2011
Electroconvection (EC) phenomena have been investigated in the nematic phase of a bent-core oxadiazole material with negative dielectric anisotropy and a frequency dependent conductivity anisotropy. The formation of longitudinal roll (LR) patterns is one
Belaissaoui, A.   +4 more
core   +1 more source

Excimer Formation in Aqueous Solutions of Hosts and Application in Synthesis

open access: yesChemPhotoChem, Volume 10, Issue 4, April 2026.
This review explores how host‐mediated excimer formation in water, facilitated by supramolecular confinement enhances photochemical synthesis. By improving solubility, local concentrations, and orientational control, these systems can boost efficiency and selectivity in reactions like photocycloadditions and photodimerizations.
Doğan Akbulut   +3 more
wiley   +1 more source

Domain Walls and Anchoring Transitions Mimicking Nematic Biaxiality in the Oxadiazole Bent-Core Liquid Crystal C7

open access: yes, 2015
We investigate the origin of secondary disclinations that were recently described as a new evidence of a biaxial nematic phase in an oxadiazole bent-core thermotropic liquid crystal C7.
Acharya   +61 more
core   +1 more source

Inductive queries for a drug designing robot scientist [PDF]

open access: yes, 2010
It is increasingly clear that machine learning algorithms need to be integrated in an iterative scientific discovery loop, in which data is queried repeatedly by means of inductive queries and where the computer provides guidance to the experiments that ...
A. Lingas   +10 more
core   +1 more source

Structure‐Guided Optimization and Biological Validation of 1,3,4‐Thiadiazole‐Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

open access: yesDrug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel   +9 more
wiley   +1 more source

Light propagation and fluorescence quantum yields in liquid scintillators

open access: yes, 2015
For the simulation of the scintillation and Cherenkov light propagation in large liquid scintillator detectors a detailed knowledge about the absorption and emission spectra of the scintillator molecules is mandatory. Furthermore reemission probabilities
Buck, C., Gramlich, B., Wagner, S.
core   +1 more source

Selection of turning-on fluorogenic probe as protein-specific detector obtained via the 10BASEd-T [PDF]

open access: yes, 2017
In order to obtain a molecular probe for specific protein detection, we have synthesized fluorogenic probe library of vast diversity on bacteriophage T7 via the gp10 based-thioetherification (10BASEd−T).
Masumi Taki   +3 more
core   +2 more sources

Sustainable Rewritable Paper Enabled by Colored Aqueous Inks for Writing, Painting, and Printing Applications

open access: yesEcoMat, Volume 8, Issue 4, April 2026.
A sustainable rewritable paper platform is developed using biopolymer‐based aqueous colored inks and organic acid–treated substrates. Localized protonation induces in situ fibrous hydrogel network formation that anchors dyes for stable handwriting, painting, and inkjet printing.
Damini Jagankar   +2 more
wiley   +1 more source

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