Results 71 to 80 of about 25,633 (260)

Synthesis and Characterization of 1,3,4-Oxadiazoles Derived From 9-Fluorenone

مجلة بغداد للعلوم, 2013
In the present work, 9-fluorenone-2-carboxylic acid methyl ester (1) was prepared from 9-fluorenone-2-carboxylic acid and then converted into the acid hydrazide (2).
Baghdad Science Journal
doaj   +1 more source

2‐Pyrazoline‐5‐One Derivative Suppresses Cell Proliferation and Induces Apoptosis With Upregulation of Bax in Breast Cancer Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
2‐Pyrazoline‐5‐one derivative inhibits proliferation and migration and induces Bax‐mediated apoptosis in breast cancer cells. ABSTRACT The most common cancer in women worldwide is still breast cancer. Among its subtypes, luminal A and triple‐negative breast cancers present significant therapeutic challenges due to intrinsic drug resistance and absence ...
Sevgi Kocyigit Sevinc, Ş. Güniz Küçükgüzel, Sevim Rollas, Fulya Yukcu   +3 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Revisiting the Formation Mechanism of 1,3,4-Oxadiazole-2(3H)‑ones from Hydrazonyl Chloride and Carbon Dioxide

, 2018
The reaction mechanism for the synthesis of 1,3,4-oxadiazole-2­(3H)-ones from hydrazonyl chloride and CO2 in the presence of CsF/18-crown-6 and toluene, is revisited via density functional theory computations.
Jorge Barroso (3594497), Fernando Murillo (5365844), Gustavo Ávila (5860646), Sudip Pan (1542133), Gabriel Merino (1413124), María A. Fernández-Herrera (1413115), María G. de los Santos (5860643)   +6 more
core   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Planejamento, síntese e caracterização de derivados do 9,10-bis(5-fenil-1,3,4-oxadiazol-2-IL)Antraceno [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015Neste trabalho é descrito o planejamento, síntese e caracterização de uma série de novos ...
Ratto Neto, Carlos Alberto
core  

Synthesis and photophysical properties of novel oxadiazole substituted BODIPY fluorophores

, 2022
Using 3-phenyl-5-(5-phenyl-1H-pyrrol-3-yl)-1,2,4-oxadiazole, BODIPYs with the oxadiazole groups at the 1,7-positions were prepared and their photophysical properties were characterized.
Zhilyaev D.I., Chulkin P., Talarico G., Matveeva M.D., Miftyakhova A.R., Efimov I.V., Voskressensky L.G., Janasik P.   +7 more
core   +2 more sources

Incorporation of an Extended Electron‐Deficient Central Block Into Small‐Molecule Acceptors Toward Enhanced‐Performance Organic Solar Cells

Aggregate, Volume 7, Issue 6, June 2026.
Two novel extended electron‐deficient central cores (Tz‐Qx, Dz‐Qx) with F/Cl‐substituted terminal groups synergistically optimize small molecule acceptors. Tz‐Qx‐4F outperforms Dz‐Qx‐based counterparts, achieving 19.50% PCE (29.3 mA cm−2 JSC) when blended with D18, thus providing valuable insights for designing high‐performance organic solar cell ...
Lan Xie, Yizhi Jiang, Lu Chen, Dingding Qiu, Jicheng Yi, Han Yu, Jianqi Zhang, Zhixiang Wei, Joshua Yuk Lin Lai, Shengjian Liu, He Yan   +10 more
wiley   +1 more source

Synthesis, Characterization and Effect of bis-1,3,4Oxadiazole Containing Glycine Moiety on the Activity of Some Transferase Enzymes.

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
  We described herein the synthesis of novel bis-1,3,4-oxadiazole containing glycine moiety. N-{5-[5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-yl-sulfanyl]-1,3,4-oxadiazole-2-yl-methyl}-4methoxybenzamide was fully characterized by elemental analysis, FT-IR ...
I. H. R. Tomi, A. H. J. Al-Qaisi, Z. H. J. Al-Qaisi   +2 more
doaj  

Synthesis and Antimicrobial Activity of Some Derivatives on the Basis (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic Acid Hydrazide

Molecules, 2006
(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide (2) was prepared from (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester (1) and 100% hydrazine hydrate.
Elizabeth Has-Schon, Frane Cacic, Mladen Trkovnik, Milan Cacic   +3 more
doaj   +1 more source