Results 71 to 80 of about 10,824 (225)

Recent advancements in oxadiazole-based anticancer agents [PDF]

open access: yes, 2017
Oxadiazole ring system occupies a significant position among heterocyclic templates for medicinal compounds due to its wide spectrum of biological activities.
Rasool, Irfan   +6 more
core   +2 more sources

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Planejamento, síntese e caracterização de derivados do 9,10-bis(5-fenil-1,3,4-oxadiazol-2-IL)Antraceno [PDF]

open access: yes, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015Neste trabalho é descrito o planejamento, síntese e caracterização de uma série de novos ...
Ratto Neto, Carlos Alberto
core  

Characterization of Structure, Properties, and Energetic Performance of a 1:1 Ammonium Dinitramide‐3,4‐Diaminofurazan Cocrystal

open access: yesPropellants, Explosives, Pyrotechnics, Volume 51, Issue 7, Page 1044-1057, July 2026.
Ammonium dinitramide (ADN) and 3,4‐Diaminofurazan (DAF) form a 1:1 energetic cocrystal. We report its crystal structure and spectroscopic signature and evaluate thermal stability, decomposition behavior, hygroscopicity, and combustion properties. Propellant performance calculations benchmark the material against guanylurea dinitramide (GuDN) and ...
Peter Schultz   +2 more
wiley   +1 more source

Binary‐Solvent‐Programmed Single‐Step Inkjet Printing of Self‐Confined Micro‐Inlaid OLED Arrays

open access: yesSmall Methods, Volume 10, Issue 14, 22 July 2026.
Solvent‐programmed micro‐inlay inkjet printing enables lithography‐free, high‐resolution μ‐OLED arrays in a single step. A thermodynamically tuned 3:1 (w/w) chloroform/dichloroethane blend not only drives interfacial phase separation between the solute and polymers but also stabilizes droplet ejection, forming rim‐confined emissive domains in one pass.
JaeWoo Park   +5 more
wiley   +1 more source

Synthesis of new oxadiazole derivatives as potent and selective FXR antagonists [PDF]

open access: yes, 2019
In this comunication was reported that the manipulation of the oxadiazole scaffold, modifying both substituents at C-3 and C-5, led to the synthesis of a small library of derivatives some of which characterized by a potent FXR antagonistic activity and
Claudia Finamore   +5 more
core   +1 more source

Synthesis, Characterization and Effect of bis-1,3,4Oxadiazole Containing Glycine Moiety on the Activity of Some Transferase Enzymes.

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
  We described herein the synthesis of novel bis-1,3,4-oxadiazole containing glycine moiety. N-{5-[5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-yl-sulfanyl]-1,3,4-oxadiazole-2-yl-methyl}-4methoxybenzamide was fully characterized by elemental analysis, FT-IR ...
I. H. R. Tomi   +2 more
doaj  

Synthesis and characterization of new phthalimides and succinimides substituted with 1,3,4-oxadiazole ring [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
A series of new phthalimides and succinimides connected to 1,3,4-oxadiazole moiety were synthesized via multistep synthesis. The first step involved synthesis of six 5- substituted 2- amino-1,3,4-oxadiazoles by oxidative cyclization of substituted ...
Ahlam Marouf Al-Azzawi   +1 more
doaj   +1 more source

Unusual backfolded binding poses of BAZ2A bromodomain binders

open access: yesActa Crystallographica Section D, Volume 82, Issue 7, Page 776-784, July 2026.
We identified BAZ2A‐binding compounds assuming a peculiar, almost enclosed, conformation. These molecules pose a basis for the development of potent BAZ2A macrocyclic inhibitors, as performed for other bromodomains.BAZ2A is a large multidomain protein overexpressed in aggressive prostate cancer, where it potentiates migration and invasion of other ...
Andrea Dalle Vedove   +5 more
wiley   +1 more source

A Review on Oxadiazole [PDF]

open access: yes, 2020
Oxadiazoles are important five membered heterocyclic classes of compounds with 2 azo groups and one oxygen in its ring system. It is widely researched as a lead compound for designing potent bioactive agents.
Mohammad Salam   +4 more
core  

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