Results 151 to 160 of about 28,539 (273)

Design, Synthesis and Biological Evaluation of Oxadiazole-Biphenyl Derivatives as Small Molecule Inhibitors Targeting PD-1/PD-L1 Immune Checkpoint. [PDF]

ACS Med Chem Lett
Xie L, Zhu M, Zhao T, Pei Y, Wei B, Zhu S, Chen J, Zhang H, Zhou J.   +8 more
europepmc   +1 more source

Design, synthesis and antiproliferative, apoptotic, and immunomodulatory properties of new heteroaryl pyridine-linked 1,2,4-oxadiazoles as prospective dual EGFR/BRAF^V600E inhibitors. [PDF]

RSC Adv
Gomaa HAM, Shaker ME, Alzarea SI, Alatwi E, Mohamed FAM, Abdullah Alzahrani AY, Alyami BA, Bräse S, Rabea SM, Youssif BGM.   +9 more
europepmc   +1 more source

Synthesis, enzyme kinetics and computational evaluation of N-(β-d-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors [PDF]

, 2017
Begum, Jaida, Docsa, Tibor, Gergely, Pál, Hayes, Joseph M., Juhász, László, Polyák, Mária, Somsák, László, Szilágyi, Bence, Varga, Gergely   +8 more
core   +1 more source

Lonidamine-1,3,4-oxadiazole derivatives with antiproliferative effects on HCT116 colon cancer cell lines: biological evaluation, ADMET, and computational studies. [PDF]

RSC Adv
Bhat RM, Priyadarshini AN, Sudhanva MS, Muddapur GV, Alhussieni K, K RK, Keri RS.   +6 more
europepmc   +1 more source

Development in medicinal chemistry via oxadiazole derivatives: patent spotlight 2020–2024

Mehwish Solangi, Fouzia Naz, Syed Abid Ali, Khalid Mohammed Khan   +3 more
openalex   +2 more sources

Synthesis, Urease Inhibition, Antioxidant, Antibacterial, and Molecular Docking Studies of 1,3,4-Oxadiazole Derivatives [PDF]

, 2012
Muhammad Asif Hanif, Khurram Shoaib, M. Saleem, Nasim Hasan Rama, Sumera Zaib, Jamshed Iqbal   +5 more
openalex   +1 more source

Bridging mechanism and design: modern medicinal chemistry approaches to thymidylate synthase inhibitors. [PDF]

RSC Adv
Al-Karmalawy AA, Eissa ME, Yousef TA, Al Khatib AO, Hawas SS.   +4 more
europepmc   +1 more source

Design, synthesis and antiproliferative activity of oxadiazole derivatives as potent glycogen synthase kinase-3/histone deacetylase 6 dual inhibitors. [PDF]

J Enzyme Inhib Med Chem
Ye C, Chen Z, Jiang J, Li J, Kong R, Liu S, Chen X, Xu Z.   +7 more
europepmc   +1 more source

Energetic alliance of tetrazole-1-oxides and 1,2,5-oxadiazoles

, 2014
Dennis Fischer, Thomas M. Klapötke, Marius Reymann, Jörg Stierstorfer, Maurus B. R. Völkl   +4 more
openalex   +2 more sources

Exploring 1,3,4-oxadiazolyl sulfide derivatives as antidiabetic candidates: synthesis, antioxidant activity, SAR-study, molecular docking, and DFT-insights. [PDF]

BMC Chem
Khalaf NA, Said GE, Abdel-Latif E, Metwally HM.   +3 more
europepmc   +1 more source