Results 161 to 170 of about 10,824 (225)

Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency. [PDF]

Mol Ther Nucleic Acids
Fiduccia I, Vitale E, Varrica R, Ricci D, Marino S, Zito A, Pace A, Colige A, Moutschen M, Borutzki Y, Bileck A, Meier-Menches SM, Lentini L, Pibiri I.   +13 more
europepmc   +1 more source

Salt Formation of the Alliance of Triazole and Oxadiazole Towards Balanced Energy and Safety. [PDF]

Materials (Basel)
Liu Y, Wang M, Men J, Li B, Feng S, Zhu S, Liu G, Gou R, Zhang S, Lu M, Yang L.   +10 more
europepmc   +1 more source

Insight into the Anticancer Potential of Imidazole-Based Derivatives Targeting Receptor Tyrosine Kinases. [PDF]

Pharmaceuticals (Basel)
Al-Hussain SA, Dawood DH, Farghaly TA, Abu Alnjaa AM, Zaki MEA.   +4 more
europepmc   +1 more source

Targeting ALDH7A1 with covalent inhibitors reveals new chemical space for prostate cancer therapy. [PDF]

J Enzyme Inhib Med Chem
Gallo R, Scarano A, Gianquinto E, Franzini G, Antonini G, Montalbano S, Palmieri C, Conti P, Spyrakis F, Borsari C, Bruno S.   +10 more
europepmc   +1 more source

<i>One-pot</i> dearomatizative telescoped addition of <i>C</i>-nucleophiles to fluorinated 1,2,4-oxadiazoles followed by regioselective <i>N</i>-functionalization.

Org Chem Front
Castiglione D, Amata S, Lauria F, Maranzana A, Baldino S, Prado-Roller A, Castoldi L, Palumbo Piccionello A, Pace V, Comas Iwasita EI.   +9 more
europepmc   +1 more source

Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery [PDF]

Pharmaceuticals, 2020
Five-membered 1,2,4-oxadiazole heterocyclic ring has received considerable attention because of its unique bioisosteric properties and an unusually wide spectrum of biological activities.
Janusz Rachon, Konrad Kubiński, Mateusz Dasko   +2 more
exaly   +2 more sources

Synthesis and antimicrobial activity of some 1,3,4-oxadiazole derivatives [PDF]

Il Farmaco, 2002
Six new 5-(1-/2-naphthyloxymethyl)-1,3,4-oxadiazole-2(3H)-thione, 2-amino-5-(1-/2-naphthyloxymethyl)-1,3,4-oxadiazole, 5-(1-/ 2-naphthyloxymethyl)-1,3,4-oxadiazole-2(3H)-one derivatives have been synthesized from 1-and/or 2-naphthol.
Melike Ekizoğlu, Erhan Palaska, Meral Özalp   +2 more
exaly   +2 more sources

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Banana-Shaped 1,2,4-Oxadiazole Analogues of 1,3,4-Oxadiazoles

Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals, 2001
Abstract In the last years bent banana-shaped mesomorphic molecules found an increasingly great interest among theoreticians and experimentalists due to the nature of this type of liquid crystals to exhibit a spontaneous polarization in the absence of any chiral group in the molecules.
S. I. TORGOVA, L. A. KARAMYSHEVA, T. A. GEIVANDOVA, STRIGAZZI, Alfredo   +3 more
openaire   +2 more sources

Perfluoro-1,3,4-oxadiazoles

Journal of Fluorine Chemistry, 1992
Abstract Some new polyfluorinated 1,3,4-oxadiazoles have been obtained via a two-step method. The cycloadditions of the 1,3,4-oxadiazoles have been studied and an analysis of the energies of the frontier orbitals calculated by the MNDO method indicates a LUMO-dependent pathway for cycloaddition.
N.V. Vasiliev, Yu.E. Lyashenko, A.E. Patalakha, G.A. Sokolski   +3 more
openaire   +1 more source