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A Preferred Synthesis of 1,2,4‐Oxadiazoles
Synthetic Communications, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Brenda Pipik +3 more
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Oxadiazole grafts in peptide macrocycles
Nature Chemistry, 2016Synthetic methods that provide control over macrocycle conformation and, at the same time, mitigate the polarity of peptide bonds represent valuable tools for the discovery of new bioactive molecules. Here, we report a macrocyclization reaction between a linear peptide, an aldehyde and (N-isocyanimino)triphenylphosphorane.
John R, Frost +2 more
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Poly‐1,3,4‐oxadiazoles. III. Alicyclic poly‐1,3,4‐oxadiazoles
Die Makromolekulare Chemie, 1966AbstractSome alicyclic poly‐1,3,4‐oxadiazoles were prepared from cycloalkanedicarboxylic dihydrazides or from cycloalkanedicarboxylic acids and hydrazine sulfate by solution polycondensation in polyphosphoric acid. These polymers were characterized by high melting temperature.
Yoshio Iwakura +2 more
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2015
[288-37-9] C2H2N2O (MW = 70.050) InChI = 1S/C2H2N2O/c1-2-4-5-3-1/h1-2H InChIKey = JKFAIQOWCVVSKC-UHFFFAOYSA-N (small-molecule heterocyclic pharmacophore) Physical Data: bp 98 °C, mp −28 °C. Alternate Name: furazan. Handling: compound known to possess potent biological activities in humans; toxic by skin contact or ...
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[288-37-9] C2H2N2O (MW = 70.050) InChI = 1S/C2H2N2O/c1-2-4-5-3-1/h1-2H InChIKey = JKFAIQOWCVVSKC-UHFFFAOYSA-N (small-molecule heterocyclic pharmacophore) Physical Data: bp 98 °C, mp −28 °C. Alternate Name: furazan. Handling: compound known to possess potent biological activities in humans; toxic by skin contact or ...
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2015
[288-43-7] C2H2N2O (MW 70.06) InChI = 1S/C2H2N2O/c1-2-5-4-3-1/h1-2H InChIKey = WCPAKWJPBJAGKN-UHFFFAOYSA-N (1,5-electrocyclic ring opening3; 1,3-dipolar cycloaddition7 with alkynes and nitrous oxide)
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[288-43-7] C2H2N2O (MW 70.06) InChI = 1S/C2H2N2O/c1-2-5-4-3-1/h1-2H InChIKey = WCPAKWJPBJAGKN-UHFFFAOYSA-N (1,5-electrocyclic ring opening3; 1,3-dipolar cycloaddition7 with alkynes and nitrous oxide)
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Mass spectrometric analysis of 1,2,4‐Oxadiazoles and 4,5‐Dihydro‐1,2,4‐Oxadiazoles
Mass Spectrometry Reviews, 2004Abstract1,2,4‐Oxadiazoles and 4,5‐dihydro‐1,2,4‐oxadiazoles are an interesting class of compounds because of their pharmacological and other properties. Although short descriptions of these compounds under mass spectrometric conditions exist, we thought it worthwhile to write a comprehensive review of this class of compounds.
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