Synthesis and Antimicrobial Evaluation of Some New Oxadiazoles Derived from Phenylpropionohydrazides
Molecules, 2009 In this study a series ofnew1-(2-aryl-5-phenethyl-1,3,4-oxadiazol-3(2H)-yl)ethanones 2a-e was synthesized by the cyclization of imines 1a-e using acetic anhydride. The products were evaluated for anti-bacterial and anti-fungal activity.
Mohammad Ali +3 more
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Development in medicinal chemistry <i>via</i> oxadiazole derivatives: patent spotlight 2020-2024. [PDF]
Pharm Pat AnalSolangi M, Naz F, Ali SA, Khan KM.
europepmc +3 more sources
The first metal complexes of 3,3'-bi-1,2,4-oxadiazole: A curiously ignored ligand [PDF]
, 2006 The crystal structure of 3,3'-bi-1,2,4-oxadiazole (1) reveals a planar centrosymmetric structure for this molecule in the solid state. It forms a mononuclear complex (3) with palladium(II) chloride, which is shown by X-ray crystallography to contain the ...
Richardson, C., Steel, P.J.
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Therapeutic potential of oxadiazole or furadiazole containing compounds
BMC Chemistry, 2020 As we know that, Oxadiazole or furadi azole ring containing derivatives are an important class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two carbons, one oxygen atom, two nitrogen atoms, and two double bonds is known as ...
Ankit Siwach, Prabhakar Kumar Verma
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Molecules, 2021 A series of N-pyridyl ureas bearing 1,2,4- (1a, 2a, and 3a) and 1,3,4-oxadiazole moiety (1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as well as X-ray diffraction.
Sergey V. Baykov +6 more
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Inverse electron-demand 1,3-dipolar cycloaddition of nitrile oxide with common nitriles leading to 3-functionalized 1,2,4-oxadiazoles [PDF]
, 2011 A carbamoyl-substituted nitrile oxide was generated upon treatment of easily available 2-methyl-4-nitro-3-isoxazolin-5(2H)-one with THF (not dried); the reaction proceeded efficiently even in the absence of any special reagents and reaction conditions ...
1020 +15 more
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BIOLOGICALLY ACTIVE OXADIAZOLE
Journal of Drug Delivery and Therapeutics, 2015 As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are three known isomers that is 1,2,4-oxadiazole, 1,2,3-oxadiazole and 1,2,5-oxadiazole (Figure 1.0 ...
Chhama Shukla, Sanchit Srivastav
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Quantum chemical research of the molecular structure of 3,4-dicyanofuroxan
Тонкие химические технологии, 2023 Objectives. The study set out to determine the equilibrium parameters of the 3,4-dicyanofuroxan molecule by means of molecule geometry optimization by quantum chemistry methods, verify the adequacy of the methods used, and compare the obtained results ...
I. N. Kolesnikova +3 more
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A facile synthesis of N-Z/Boc-protected 1,3,4-oxadiazole-based peptidomimetics employing peptidyl thiosemicarbazides [PDF]
, 2010 Synthesis of 1,3,4-oxadiazole containing peptidomimetics is described by a p-TsCl/pyridine-mediated cyclization of the corresponding dipeptidyl thiosemicarbazides, which are readily prepared by coupling N-protected amino acid hydrazides with amino acid ...
Lamani, R.S. +2 more
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Potassium (3-Methyl-2-oxido-1,2,5-oxadiazol-4-yl)dinitromethanide
Molbank, 2021 Furoxan derivatives enriched with explosophoric functionalities are promising compounds in the preparation of novel energetic materials. Herein, a previously unknown potassium (3-methyl-2-oxido-1,2,5-oxadiazol-4-yl)dinitromethanide (also referred to as ...
Egor S. Zhilin +2 more
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